This week's podcast focuses on strategies to improve care for patients with sickle cell disease (SCD), featuring expert insights from the 19th Annual Scientific Conference on Sickle Cell and Thalassemia (ASCAT 2024), which was held in London, UK. You will hear from Natasha Archer, MD, MPH, Harvard Medical School, Boston, MA, Subarna Chakravorty, MBBS, MRCPCH, FRCPath, PhD, King’s College Hospital NHS Trust, London, UK, Christiana Dinah, BSc, MBBS, MRes, London North West Healthcare NHS Trust, Harrow, UK, Leon Tshilolo, MD, PhD, Centre Hospitalier Monkole, Kinshasa, DR Congo, and Marsha Treadwell, PhD, University Of California San Francisco, San Francisco, CA. They speak about pain management in SCD, ongoing projects including the Universal Care Plan Project and the Sickle Eye Project, and unmet needs in Sub-Saharan Africa and from a psychosocial perspective.