In Vivo

Physicist Dr. Melvin Vopson (University of Portsmouth) joins In Vivo to explain his groundbreaking Second Law of Infodynamics — the idea that information in the universe constantly compresses and minimizes itself, the exact opposite of the Second Law of Thermodynamics.In this episode he shows how this law can derive Newton’s law of gravity as an emergent computational optimization process, why viral genomes and digital data both delete information over time, and why dark matter may actually be the hidden “code” of reality itself. We also explore the difference between a literal simulation and a self-computing universe, ancient philosophy, and profound implications for biology and evolution.Links:Reality Reloaded: The Scientific Case for a Simulated Universe on Amazon - https://a.co/d/06WYzguLDr. Vopson at the University of Portsmouth - https://www.port.ac.uk/about-us/structure-and-governance/our-people/our-staff/melvin-vopsonIn Vivo on X - https://x.com/InVivoPodOnXIn Vivo on youtube - https://www.youtube.com/@InVivoPodcastIn Vivo on Apple Podcast - https://podcasts.apple.com/us/podcast/in-vivo/id1775578563In Vivo on Amazon Podcasts - https://music.amazon.ca/podcasts/1ac4dbec-df46-4d1f-b0a1-742e9656ef44/in-vivo

In this episode, Eric Jorgenson, author of the bestselling The Almanack of Naval Ravikant and The Book of Elon, breaks down Elon Musk’s most useful ideas for students, young professionals, and anyone who wants to think and operate at a higher level.We explore:• How to apply First Principles Thinking to school, career, and life• Why you should play life like a game and optimize for what actually matters• The power of high effort optimism, parallel work, and attacking bottlenecks• Elon’s mindset on risk, feedback, and extreme ownership• Why Tesla and SpaceX attract the best young engineers• Gamification, orders of magnitude thinking, and the Idiot Index Eric also shares how he built his unique “wisdom compilation” books and what he learned after spending years curating Elon’s best ideas.

Links:The Book of Elon → https://a.co/d/04XBfSE9The Almanack of Naval Ravikant → https://a.co/d/05uYzef9Eric Jorgenson on X → https://x.com/EricJorgensonIn Vivo on Youtube - https://www.youtube.com/@InVivoPodcastIn Vivo on Spotify - https://open.spotify.com/show/5GBvPPvSx52O6ILuam4LoX?si=6c903566ae7b4761&nd=1&dlsi=254f9f5e78194002In Vivo on Apple Podcast - https://podcasts.apple.com/us/podcast/in-vivo/id1775578563In Vivo on Amazon Podcasts - https://music.amazon.ca/podcasts/1ac4dbec-df46-4d1f-b0a1-742e9656ef44/in-vivo

What is energy in biology? In this eye-opening conversation, biophysicist Dr. Nirosha Murugan reveals that life is not just chemistry or genes, it is structured, patterned energy in constant flow. She explains why the dynamic flow of energy is what separates a living cell from a dead one, how cells emit ultra-weak light called biophotons, and why diseased cells (including cancer) have completely different light signatures.Dr. Murugan also breaks down the groundbreaking Energy Resistance Principle (ERP) she co-developed with Dr. Martin Picard, explores intelligence without a brain in slime molds and planaria, bioelectricity in tissue patterning and regeneration, and her lab’s work using electromagnetic fields to reprogram cancer cells.

Connect with Dr. Nirosha Murugan:X (Twitter): https://x.com/niroshajmuruganThe Murugan Lab at Wilfrid Laurier University: https://themuruganlab.com/Martin Picard’s Substack (co-author of the Energy Resistance Principle): https://martinpicard.substack.com/#Biophotons #EnergyResistancePrinciple #NiroshaMurugan #QuantumBiology #Bioelectricity #Biophysics #CancerDetection #EnergyInBiologyIn Vivo on X - https://x.com/InVivoPodOnXIn Vivo on Youtube: https://www.youtube.com/@InVivoPodcastIn Vivo on Apple Podcast - https://podcasts.apple.com/us/podcast/in-vivo/id1775578563In Vivo on Amazon Podcasts - https://music.amazon.ca/podcasts/1ac4dbec-df46-4d1f-b0a1-742e9656ef44/in-vivo

In this deep-dive conversation, evolutionary biologist Dr. Bret Weinstein joins me to explore his groundbreaking hypothesis: that Variable Number Tandem Repeats (VNTRs) function as genomic “sliders”, numerical variables stored in non-coding DNA that allow evolution to rapidly explore adjacent forms and solve major gaps in neo-Darwinism.We discuss why evolutionary theory has stalled for decades, how VNTRs could explain fast morphological transitions (like shrew-to-bat), the adjacent possible, telomeres as proof-of-concept, and why the standard story of allelic variation may be far less powerful than we’ve been told.Bret also reacts to four original extensions I propose, including VNTRs as error-correction codes, environmental resonators, and microbiome tuning.Bret Weinstein:X / Twitter: https://x.com/BretWeinsteinDark Horse Podcast: https://darkhorsepodcast.org/Buy the book: A Hunter-Gatherer’s Guide to the 21st Century https://www.amazon.com/dp/B08WDN2RZB/?bestFormat=true&k=hunter%20gathers%20guide%20to%20the%2021st%20century&ref_=nb_sb_ss_w_scx-ent-bk-ww_k0_1_21_de&crid=2KPWO9JBHW2AN&sprefix=a%20hunter%20gather%27s%20guiIn Vivo on X - https://x.com/InVivoPodOnXIn Vivo on Youtube: https://www.youtube.com/@InVivoPodcast

In Vivo on Apple Podcast - https://podcasts.apple.com/us/podcast/in-vivo/id1775578563In Vivo on Amazon Podcasts - https://music.amazon.ca/podcasts/1ac4dbec-df46-4d1f-b0a1-742e9656ef44/in-vivo

Do we actually have free will, or is it just a neurobiological illusion? In this fascinating episode, neuroscientist and bioengineer Dr. Nic Rouleau explains why our feeling of making choices might just be a hardwired neurological superstition.We dive deep into the world of cybernetics, exploring why living biological computers are currently vastly more efficient at learning than modern artificial intelligence. Dr. Rouleau, who runs the Self-Organizing Units Lab (SOUL) at Laurier University, shares his groundbreaking work on growing human neurons in a dish and what it tells us about cognition. We also explore the concept of "mind blindness," the profound intelligence of plants, panpsychism, and the mind-bending future of "consciousness engineering", including whether we will ever be able to successfully transfer human consciousness to a machine.

Papers mentioned:1. Free Will• A Neuropsychological Basis for the Experience of Free Will Under Causal Determinism Authors: Kansala, Cicek, Rouleau et al. Preprint: https://osf.io/preprints/psyarxiv/fk3yt_v12. Cybernetics & Tissue Engineering• A Cybernetic Framework for Synthetic Biological Intelligence in the Era of Neural Tissue Engineering Authors: Étienne P. Sellar, Nicolas Rouleau Preprint: https://osf.io/preprints/psyarxiv/md2wf_v1• Learning and Synaptic Plasticity in 3D Bioengineered Neural Tissues Authors: Nicolas Rouleau, Dana M. Cairns, William Rusk, Michael Levin, David L. Kaplan Published: Neuroscience Letters (2021) Link: https://www.sciencedirect.com/science/article/abs/pii/S0304394021001774• Functional Bioengineered Models of the Central Nervous System Authors: Nicolas Rouleau, Nirosha J. Murugan, David L. Kaplan Published: Nature Reviews Bioengineering (2023) Link: https://www.nature.com/articles/s44222-023-00027-7• Toward Studying Cognition in a Dish Authors: Nicolas Rouleau, Nirosha J. Murugan, David L. Kaplan Published: Trends in Cognitive Sciences (2021) Link: https://www.cell.com/trends/cognitive-sciences/abstract/S1364-6613(21)00007-33. Mind Blindness• Brains and Where Else? Mapping Theories of Consciousness to Unconventional Embodiments Authors: Nicolas Rouleau, Michael Levin Preprint (in press with Philosophical Transactions): https://osf.io/preprints/psyarxiv/va5mk_v1• The Multiple Realizability of Sentience in Living Systems and Beyond Authors: Nicolas Rouleau, Michael Levin Published: eNeuro (2023) Link: https://www.eneuro.org/content/10/11/ENEURO.0375-23.2023.abstract• Discussions of Machine Versus Living Intelligence Need More Clarity Authors: Nicolas Rouleau, Michael Levin Published: Nature Machine Intelligence (2024) Link: https://www.nature.com/articles/s42256-024-00955-yRouleau Lab: https://rouleaulab.com X/Twitter: @DrNRouleau Wilfrid Laurier University profile: https://www.wlu.ca/academics/faculties/faculty-of-science/faculty-profiles/nicolas-rouleau/index.htmlIn Vivo on X - https://x.com/InVivoPodOnXIn Vivo on Youtube: https://www.youtube.com/@InVivoPodcastIn Vivo on Apple Podcast - https://podcasts.apple.com/us/podcast/in-vivo/id1775578563In Vivo on Amazon Podcasts - https://music.amazon.ca/podcasts/1ac4dbec-df46-4d1f-b0a1-742e9656ef44/in-vivo

In this episode of In Vivo Podcast, Dr. Antonei Csoka, biogerontologist and Director of the Epigenetics Laboratory at Howard University College of Medicine, shows how studying Hutchinson-Gilford Progeria Syndrome, the most extreme accelerated aging disease, is giving us the keys to achieving radical longevity and possibly biological immortality.As one of the scientists who discovered the LMNA gene mutation responsible for progeria, Dr. Csoka explains how this tragic condition is not just a mimic of aging, but actual aging running at extreme speed. The same core mechanisms we see in normal aging like nuclear distortion, telomere loss, DNA damage, epigenetic changes, and especially cellular senescence are all dramatically accelerated in these patients.By understanding progeria, we gain powerful insights into how to slow, stop, or even reverse the aging process itself.Dr. Csoka makes a compelling case that biological immortality may be achievable within this century.#longevity #biologicalimmortality #progeria #antiaging #CellularSenescence #lifeextension #agingresearch #cryonics #YamanakaFactors #MetaDisease #InVivoPodcastDr. Csoka's X page - https://x.com/abcsokaDr. Csokas' Instagram - https://www.instagram.com/abcsoka/reels/?__d=1In Vivo on X - https://x.com/InVivoPodOnXIn Vivo on Youtube - https://www.youtube.com/@InVivoPodcastIn Vivo on Apple Podcast - https://podcasts.apple.com/us/podcast/in-vivo/id1775578563In Vivo on Amazon Podcasts - https://music.amazon.ca/podcasts/1ac4dbec-df46-4d1f-b0a1-742e9656ef44/in-vivo

What if your brain is actually a "reducing valve" that filters out most of reality? In this episode, we dive deep into the world of DMT (N-Dimethyltryptamine) and 5-MeO-DMT with Dr. Chris Timmermann from the Center for Psychedelic Research at Imperial College London. His work focuses on the effects of DMT on the human brain and how it can help us understand the relationship between brain activity and conscious experience. In this episode we explore how these powerful molecules are being used as tools to study the very limits of human consciousness and the nature of reality itself.Dr. Timmermann’s Lab - https://www.uccr.uk/Dr. Timmermann on X - @neurodeliaIn Vivo on X - https://x.com/InVivoPodOnXIn Vivo on Youtube - https://www.youtube.com/@InVivoPodcastIn Vivo on Apple Podcast - https://podcasts.apple.com/us/podcast/in-vivo/id1775578563In Vivo on Amazon Podcasts - https://music.amazon.ca/podcasts/1ac4dbec-df46-4d1f-b0a1-742e9656ef44/in-vivo

Dr. Aiello is a quantum engineer and researcher working at the intersection of quantum physics, quantum engineering, and quantum biology, to explore a provocative idea: that there may be a basal, underlying quantum layer to life itself.

Many people encounter quantum mechanics for the first time and come away thinking it’s mysterious, abstract, or even “magic.” But as Dr. Aiello explains, quantum mechanics is not only real—it is practical, engineerable, and already shaping modern technology. From quantum computers to quantum sensors, quantum engineers are building instruments that can control and manipulate quantum systems with extraordinary precision.Dr. Clarice Aiello on X - https://x.com/ClariceDAielloThe Quantum Biology Institute on LinkedIn - https://www.linkedin.com/company/quantum-biology-institute/The Quantum Biology Institute - https://www.quantumbiology.org/The QBI on X - https://x.com/QuantumBioOrgThe Quantum Biology DAO on X - https://x.com/QuantumBioDAOIn Vivo on X - https://x.com/InVivoPodOnXIn Vivo on Youtube - https://www.youtube.com/@InVivoPodcastIn Vivo on Apple Podcast - https://podcasts.apple.com/us/podcast/in-vivo/id1775578563In Vivo on Amazon Podcasts - https://music.amazon.ca/podcasts/1ac4dbec-df46-4d1f-b0a1-742e9656ef44/in-vivo

In this episode of In Vivo, we dive deep into the "Hard Problem of Consciousness" with world-renowned anesthesiologist and researcher Dr. Stuart Hameroff. For decades, the mainstream scientific community has viewed the brain as a biological computer, with consciousness being a mere byproduct of complex neural wiring. But Dr. Hameroff, alongside Nobel Laureate Sir Roger Penrose, suggests a far more radical reality.Together, they developed the Orchestrated Objective Reduction (Orch-OR) theory, which proposes that consciousness arises from quantum vibrations within microscopic structures called microtubules.Drawing on his unique perspective as an anesthesiologist—the person responsible for literally turning consciousness "off" and "on"—Dr. Hameroff explains why our subjective experience (qualia) cannot be explained by classical physics alone. 0:00 Introduction & How I Discovered Dr. Hameroff's Work1:00 Defining Consciousness: The Hard Problem & Subjective Experience2:30 Classical vs. Quantum Views of Consciousness5:00 Microtubules 101: Structure, Function & Early Research8:45 Quantum Mechanics Basics: Superposition, Entanglement & Decoherence12:15 Introducing Orch-OR: Orchestrated Objective Reduction Explained18:30 Supporting Evidence for Orch-OR & Anesthesia's Role25:00 Free Will & Non-Algorithmic Processing32:00 Potential Therapies: Alzheimer's, Dementia & Microtubule Stabilization38:45 Quantum Effects Beyond the Brain – Other Cells & Proteins?45:00 Tubulin Count & Levels of Consciousness Across Species50:30 Panpsychism & Consciousness in Non-Biological Matter55:00 Psychedelics, Dreaming & the Afterlife in Orch-OR1:02:00 Quantum Soul, Near-Death Experiences & Reincarnation Speculation1:09:00 Transcranial Ultrasound & Brain Volume Changes in Alzheimer's1:16:00 Closing Thoughts & Personal Impact of the Theory1:22:00 Final Reflections & Thanks to Dr. Hameroff#consciousness #QuantumPhysics #StuartHameroff #RogerPenrose #Microtubules #OrchOR #TheHardProblem #QuantumBiology #SciencePodcast #InVivoDr. Hameroff’s at The University of Arizona – https://hameroff.arizona.edu/ Dr. Hameroff’s X page - https://x.com/StuartHameroffIn Vivo on X - https://x.com/InVivoPodOnXIn Vivo on Youtube - https://www.youtube.com/@InVivoPodcastIn Vivo on Apple Podcast - https://podcasts.apple.com/us/podcast/in-vivo/id1775578563In Vivo on Amazon Podcasts - https://music.amazon.ca/podcasts/1ac4dbec-df46-4d1f-b0a1-742e9656ef44/in-vivo

In this episode, I sit down with Dr. Robert Malone, the scientist credited with the invention of mRNA transfection technology, to discuss the true history of one of the most important tools in molecular biology. We go beyond the mainstream headlines to explore the moment of discovery at the Salk Institute, the "stolen valor" of the 2023 Nobel Prize, and the ethical crossroads facing modern science.00:00 Introduction: The Indispensable Tools of Biology 05:30 The Fried Egg Metaphor: How the Cell Works 14:00 The "Greased Lightning" Moment at the Salk Institute 28:45 What is Transfection? The Tech Behind the Vaccines 45:15 The Truth About the 2023 Nobel Prize & "Stolen Valor" 58:30 Risks and Pitfalls of the mRNA Platform 01:12:10 The Ethical Hollowing Out of Modern Science 01:25:00 Pushing Back: Globalist Agendas and Informed Consent 01:40:00 Closing Thoughts: Where to Follow Dr. MaloneLinks to referenced papers:1. Intracellular Reverse Transcription of Pfizer BioNTech COVID-19 mRNA Vaccine BNT162b2 In Vitro in Human Liver Cell LineLink: https://www.mdpi.com/1467-3045/44/3/732. Cationic liposome-mediated RNA transfectionLink: https://www.pnas.org/doi/10.1073/pnas.86.16.60773. Reverse-transcribed SARS-CoV-2 RNA can integrate into the genome of cultured human cells and can be expressed in patient-derived tissuesLink: https://www.pnas.org/doi/10.1073/pnas.21059681184. DNA fragments detected in monovalent and bivalent Pfizer/BioNTech and Moderna modRNA COVID-19 vaccines from Ontario, Canada: Exploratory dose response relationship with serious adverse eventsLink: https://osf.io/mjc97/5. The Method of Multiple Working Hypotheses: With this method the dangers of parental affection for a favorite theory can be circumventedLink: https://www.science.org/doi/10.1126/science.148.3671.754Dr. Malone's Substack: https://www.malone.news/Dr. Malone's X profile: https://x.com/RWMaloneMDPsyWar: https://www.amazon.ca/PsyWar-Enforcing-New-World-Order/dp/1510782958/ref=sr_1_2?crid=14SN4L6BW831N&dib=eyJ2IjoiMSJ9.kLcNQ1QjDhR6ats9Jt_276W8Wsi3AfQvkcMEYyLmxNBlObiBQDVifWI5RYKxv_0KibJWGCqcCeP7R5sClwQJdFUwDlQ3ROOEKqAFqQzXo188hsAzyRCDdHlzwGia1rzMTOlI3fzWmpGre2aqjEMHpoP4t45XLN07wRvVaRRGXuhIpgWyrRMjMCKWIjGK0BX0F_5AbDrQRuiRnajPv5LQ0eiW5Mnj6HJvYIfzqhU85al-qk2RxVIe4LwilPwVvTdmVIbctzPX8LZGQFUBl-JT0XtRoSF5dCvB1vmsze24o60.91bKaGEsGCe29_Z1gwnXat_Tif8278ehIRyvxWeFvmI&dib_tag=se&keywords=robert+malone&qid=1767709572&sprefix=robert+malone%2Caps%2C117&sr=8-2Lies My Gov't Told Me: https://www.amazon.ca/Lies-My-Govt-Told-Me/dp/151077324X/ref=sr_1_3?crid=14SN4L6BW831N&dib=eyJ2IjoiMSJ9.kLcNQ1QjDhR6ats9Jt_276W8Wsi3AfQvkcMEYyLmxNBlObiBQDVifWI5RYKxv_0KibJWGCqcCeP7R5sClwQJdFUwDlQ3ROOEKqAFqQzXo188hsAzyRCDdHlzwGia1rzMTOlI3fzWmpGre2aqjEMHpoP4t45XLN07wRvVaRRGXuhIpgWyrRMjMCKWIjGK0BX0F_5AbDrQRuiRnajPv5LQ0eiW5Mnj6HJvYIfzqhU85al-qk2RxVIe4LwilPwVvTdmVIbctzPX8LZGQFUBl-JT0XtRoSF5dCvB1vmsze24o60.91bKaGEsGCe29_Z1gwnXat_Tif8278ehIRyvxWeFvmI&dib_tag=se&keywords=robert+malone&qid=1767709572&sprefix=robert+malone%2Caps%2C117&sr=8-3In Vivo on X - https://x.com/InVivoPodOnXIn Vivo on Youtube - https://www.youtube.com/@InVivoPodcastIn Vivo on Apple Podcast - https://podcasts.apple.com/us/podcast/in-vivo/id1775578563In Vivo on Amazon Podcasts - https://music.amazon.ca/podcasts/1ac4dbec-df46-4d1f-b0a1-742e9656ef44/in-vivo