"Here we have a condition that has been known medically for hundreds of years, people have received Nobel Prizes for their analysis and understanding of its genetic makeup. Given what is known about sickle cell, genomic research into treatments and cures should be amongst the low hanging fruit within the scientific development."

John James, CEO of the Sickle Cell Society and the first Black African-Caribbean Chief Executive in the NHS, believes that it is fundamental to acknowledge that inequalities exist before transformational change can happen across our health services as well as in research. Only then will we start closing the gaps in the differences in healthcare outcomes and treatments for all of the people our NHS serves.

This week, Chris and John tackle the challenges of reaching weary ethnic minority communities, the importance of role models, and the difficulties in translating exciting scientific advancements to healthcare professionals who are already under incredible pressure.