Just Now Possible

Just Now Possible

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Just Now Possible episodes

  • Building an AI Voice Agent for 360 Degree Feedback: How Your360 AI Uses State Machines, Evals, and Layered Synthesis

    Guests

    • Jared Goralnick, Co-Founder and CEO, Your360 AI
    • Eda Goksel Jackson, Head of Design, Your360 AI
    • Alex Krasun, AI Engineer, Your360 AI
    • Key Takeaways

      • They built the product one call at a time. The self-discovery agent shipped and was validated a month before feedback collection existed, and synthesis came after that.
      • A single prompt couldn't hold a structured conversation. State machines keep the agent on track while still letting it go deep when someone wants to.
      • Voice AI is not a survey. People answer three questions in their first sentence, so the agent has to track what has already been covered and decide when to push and when to move on.
      • If a customer won't let you look at conversations in the early days, that tells you something about the market. Find design partners who will, then build automated flags so humans only step in when something goes wrong.
      • Synthesis needs two kinds of evals. Structural passes catch "don't mess up" errors like misattributed feedback. Substantive passes re-run the analysis with few rules to find patterns the first pass missed.
      • In this episode

        • How interview-based 360 feedback differs from annual reviews and survey-based developmental 360s
        • The three calls with Coach Tam: self-discovery, feedback collection, and the 360 report debrief
        • Why the first debrief call broke a 60-minute platform limit, and why the median debrief is now 44 minutes
        • Using state machines to manage transitions between strengths, growth areas, and requested areas
        • Evals built from personas based on failed calls, used to regression-test model and provider upgrades
        • Automated flagging on sentiment, customer value, and product quality instead of routine transcript review
        • Usability testing a voice call: screen recordings plus follow-up interviews that compare perception with what actually happened
        • Moving from Retell to LiveKit for full control over speech-to-text, the LLM, and text-to-speech
        • Model tradeoffs for voice: personality vs. time to first token, and why reasoning models get in the way
        • Optimizing feedback collection calls for completion and low friction, including calls over the phone
        • Anonymity rules: corroboration required for critical feedback, groups shown only at three or more providers
        • Progressive reveal in the debrief so recipients process one theme at a time
        • Delivering feedback through each company's values and leadership principles
        • Organizational heat maps for interdependent teams and independent cohorts
        • What's next: turning awareness into action between a person's first and second 360
        • Resources & Links

          • Your360 AI
          • LiveKit – the open-source voice orchestration layer Your360 AI moved to
          • Retell AI – the voice platform they started on
          • Hogan Assessments – the interview-based assessment Teresa compares it to
          • Deepgram and ElevenLabs – speech-to-text and text-to-speech layers in a cascading voice stack
          • Fearless Feedback by Rebecca Glenn – the coach who helped shape the report format
          • Chapters

            00:00 Meet the Team

            01:35 What 360 Feedback Means
            04:11 Who Uses Your 360
            05:33 Origin Story and AI Fit
            08:25 How the 360 Works
            13:55 Making Voice Feel Human
            22:18 Testing and Evals
            23:43 Privacy and Observability
            27:28 Building in Stages
            32:33 Usability Testing Calls
            34:31 Testing Call Perception
            35:12 State Machines for Flow
            36:58 Flexible Transitions Tuning
            38:27 Owning the Voice Stack
            40:42 Model Tradeoffs and Costs
            42:28 Feedback Interviews Constraints
            44:49 Synthesis Goals and Anonymity
            49:11 Progressive Report Delivery
            52:02 Pattern Based Summaries
            54:25 Multi Pass QA Framework
            59:46 Org Level Insights Lenses
            01:02:45 Why Voice Beats Surveys
            01:05:58 Roadmap Awareness to Action
            01:07:30 Closing Thanks

            1 hr 9 min
          • Generating Opportunity Solution Trees with AI: How Vistaly Rebuilt Its Product Around Interview Synthesis, Evals, and Re

            Guests

            • Matt O'Connell, Co-Founder and CEO, Vistaly
            • CP Dehli, Co-Founder, Vistaly
            • Steve Klein, Co-Founder, Vistaly
            • Teresa Torres, host of Just Now Possible, building the AI synthesis services for Vistaly V2
            • Key Takeaways

              • The competition isn't good interview synthesis done faster—it's shallow synthesis that never really happened. That changes what "good enough" means.
              • Layered analysis matters more than whether a step is a pipeline or an agent. If the interview snapshot is wrong, every layer above it inherits the error.
              • Prompt changes run out. Balancing two opposing error modes took an orchestration change—moving the check into an agentic repair loop—not a better prompt.
              • Change sets can't be diffed at the end. The same input/output tree pair has multiple valid change sets, and only the semantically meaningful one makes sense to a user.
              • Users don't want to collaborate with the AI step by step. They want the answer, then the ability to correct it.
              • In this episode

                • Why Vistaly rebuilt from scratch instead of layering AI features onto V1—and shut off V1 signups to protect the rewrite
                • Rebuilding nearly all of V1's functionality in two and a half months, after three years of building it the first time
                • The V1 chat interface that walked users through insights one at a time, and why "still faster than before" wasn't fast enough
                • How V2 works: upload three interviews, generate an interview snapshot for each, then synthesize a first-draft opportunity solution tree
                • The "house of cards" problem: garbage in at the snapshot layer corrupts the tree above it
                • Using a code assertion (too many children on a node) as a cheap pre-filter before spending money on an LLM as a judge
                • Four new evals and 16 experiment variants to break a seesaw between missing subgroupings and badly framed parents
                • Why the fix was a repair loop in the orchestration, not a better prompt—and how that eval became a production guardrail
                • Teaching the agent "the rules of the game" so it logs semantic moves (merge, move, reframe) and produces reliable change sets
                • Stable IDs, data provenance, and the "basic computer science" Teresa swept under the rug in the prototype
                • What beta data revealed about interview quality: sales demos, stakeholder meetings, and LLM-generated fake transcripts uploaded as "interviews"
                • Building a 40-point system for generating realistic synthetic transcripts as test data
                • Driving tree edits through MCP, including mapping a full Jira epic backlog into the opportunity space
                • Adding an agent back to the canvas, and the versioning and rollback problem that comes with it
                • Data residency, SOC 2, GDPR, and moving to European Bedrock inference
                • Why model upgrades aren't drop-in: prompts are model- and version-specific, and Bedrock constrains tokens independently of the model
                • Resources & Links

                  • Vistaly — Opportunity solution tree software with AI-generated interview snapshots and tree synthesis
                  • Product Talk — Teresa's AI evals guide and her blog posts on building the Vistaly synthesis services
                  • Model Context Protocol — How Vistaly users drive tree edits from outside the product
                  • AWS Bedrock — Where Vistaly runs inference, including EU-hosted inference for European customers
                  • Just Now Possible episode with Banani — the canvas-plus-agent design UX Teresa references
                  • Just Now Possible episode with Zencity — the layered data pyramid Teresa references
                  • All Things Product episode on the quality of evidence, with Petra Wille
                  • Chapters

                    00:00 Meet the Founders

                    01:05 How Vistaly Began
                    03:10 Community First Partnership
                    04:56 Why Build OST Software
                    07:18 OST Explained Fast
                    10:28 Evidence Inside the Tree
                    12:56 AI Changes Discovery
                    16:58 Chat UI Experiment
                    23:00 Should AI Do Synthesis
                    27:10 Rebuilding as V2
                    32:08 Turning Off V1 Signups
                    34:43 V2 Workflow and Tensions
                    39:35 Trusting AI Outputs
                    39:56 Layered Analysis Pyramid
                    41:25 Building Better Trees
                    43:34 Bad Inputs and Coaching
                    47:20 Teaching Through Software
                    50:12 Evals and Guardrails
                    55:23 Deterministic Change Sets
                    01:00:54 UX for Tree Updates
                    01:07:12 Chat Agents and Versioning
                    01:11:17 Privacy Compliance Tradeoffs
                    01:15:06 Model Selection Reality
                    01:17:32 What Comes Next
                    01:19:08 Closing and Links

                    1 hr 20 min
                  • Creating Aha! Builder: Concept to Code, No Engineers Required

                    Guests

                    • Brian De Haaff, CEO and Co-Founder, Aha!
                    • Chris Waters, CTO and Co-Founder, Aha!
                    • Sarah Moisan-Thomas, Senior Product Manager for Aha! Builder, Aha!
                    • Key Takeaways

                      • Aha! is fully bootstrapped, remote-first, and profitable—built by product people, for product people
                      • Containerized infrastructure proved too wasteful for AI app building at scale, pushing Aha! to rebuild on a single-instance, multi-tenant architecture
                      • Deterministic, pre-built components (authentication, SSO, database, email) cut token cost and guarantee reliability that AI-generated code can't
                      • A multi-phase, multi-agent pipeline—design system, then prototype, then backend—produces better outcomes than a single open-ended chat prompt
                      • As building gets easier, knowing what to build becomes the product manager's real differentiator
                      • In this episode

                        • Aha!'s 13-year bootstrapped, remote, no-salespeople business model
                        • The five-step discovery framework Aha! uses for every new product, including Builder
                        • Why their first containerized version was too slow and expensive to scale
                        • Rebuilding for a single-instance, multi-tenant architecture
                        • Reusing the agent framework and tool set originally built for "Elle"—Aha!'s roadmapping AI assistant
                        • Deterministic components for authentication, SSO, database access, and email
                        • The multi-agent, multi-phase build pipeline: design system, then prototype, then full application
                        • Enterprise governance: authentication policies, deployment guardrails, and PII/PHI considerations
                        • Why Aha! is optimizing for prototypes, proofs of concept, and internal "meta applications"—not primary line-of-business apps
                        • What's next: expanded design systems and tighter feedback loops across Aha!'s product suite
                        • Resources & Links

                          • Aha!
                          • Chapters

                            00:00 Meet the Aha! Team

                            00:19 Aha! Bootstrapped Remote Story
                            01:29 What Is Aha Builder
                            02:27 Leaders Stay Hands On
                            04:49 Origin and AI Shift
                            07:44 Why Build in Aha!
                            14:12 Discovery Framework
                            17:50 From Slides to Early Access
                            21:40 Proof of Concept Approach
                            23:36 Under the Hood Architecture
                            27:01 Agent Tools and UX
                            30:59 Deterministic Components
                            33:42 Skills Docs and Iteration
                            35:48 Higher Level Building Blocks
                            36:33 Knowing What To Build
                            38:57 Builder UX For PMs
                            44:10 Enterprise Governance Guardrails
                            47:29 What Builder Is For
                            50:39 PII Security And Compliance
                            53:15 Quality Evals And Pricing
                            55:29 V8 Isolates Architecture
                            58:22 Multi Agent Build Pipeline
                            01:01:14 Roadmap Design And Feedback
                            01:03:01 PMs Engineers And PR Flow
                            01:05:52 Wrap Up And Thanks

                            1 hr 7 min
                          • Building AI for Women's Health: How Hertility Combined Bayesian Diagnosis and Scan Automation

                            Guests

                            • Tulsi Patel, Director of Product and Technology, Hertility
                            • Lorna Brightmore, Head of Data and AI, Hertility
                            • Jack Pickard, Head of Engineering, Hertility
                            • In this episode

                              • What makes Hertility's data set unique: seven years of linked symptoms, blood tests, and pelvic scans from over a million women
                              • How Gyn.AI uses a Bayesian network to give clinicians probability-based diagnoses instead of binary yes/no calls
                              • Why showing clinicians the reasoning behind a diagnosis—not just the label—builds trust and speeds up triage
                              • Guarding against automation bias with holdout sets and independent, fresh-eyes review
                              • Inside the scan automation pipeline: classifying ultrasound images, detecting follicles, and measuring ovarian volume more precisely than manual methods
                              • Using an agentic loop to check AI-drafted clinical letters against patient data and catch hallucinations before a human sees them
                              • The infrastructure challenge of securely piping DICOM ultrasound images from third-party scan providers into Hertility's systems
                              • How Hertility handles PII and PHI: pseudonymization, data minimization, and running models in-house on AWS Bedrock
                              • Why treating healthcare regulation as a product requirement from day one makes AI products more scalable, not slower
                              • Key Takeaways

                                • Probabilistic, transparent AI outputs build more clinician trust than binary classifications.
                                • Guardrails against automation bias are as important as the model itself.
                                • Data minimization and in-house infrastructure make it possible to build AI responsibly with sensitive health data.
                                • Treating regulation as a design constraint from day one makes AI products more defensible and scalable, not slower.
                                • Resources & Links

                                  • Hertility — At-home hormone testing and reproductive health diagnostics for women in the UK and Ireland
                                  • AWS Bedrock — The platform Hertility uses to run LLMs in-house under its own governance and regulatory controls
                                  • PyTorch — The foundation for Hertility's in-house image classification and contouring models
                                  • Chapters

                                    00:00 Meet the Team

                                    00:13 What Hertility Does
                                    01:51 How Customers Access It
                                    04:06 A Unique Women’s Health Dataset
                                    07:03 Mission and Efficiency with AI
                                    10:03 Why Long Assessments Convert
                                    13:52 Before AI Workflows
                                    16:52 Research Publications and Impact
                                    18:48 GynAI Reducing Time to Diagnosis
                                    21:21 Triage and Clinician Support
                                    24:37 Keeping Patient UX the Same
                                    26:12 Bayesian Network and Explainability
                                    30:19 Multiple Diagnoses and Probabilities
                                    32:37 Probabilistic Diagnosis Shift
                                    33:50 Clinician Adoption and Workflow Fit
                                    34:58 Communicating Medical Uncertainty
                                    36:43 Scan Automation Overview
                                    40:30 In House Image Analysis
                                    44:25 DICOM Pipeline Engineering
                                    47:30 Evals and Automation Bias
                                    50:31 LLM Letter Guardrails
                                    56:47 PHI Handling and Regulations
                                    01:00:43 Infrastructure Choices and Wrap Up

                                    1 hr 5 min
                                  • From COVID Pivot to AI World Building: How Snapbar Reinvented the Photo Experience

                                    Guests

                                    • Sam Eitzen, Co-founder & CEO, Snapbar
                                    • Joe Eitzen, Co-founder & CPO, Snapbar
                                    • Patrick Ellis, CTO, Snapbar
                                    • You'll hear how they:

                                      • Pivoted from physical photo booths to a cross-platform virtual product in spring 2020 using WebRTC—built from first principles out of necessity
                                      • Integrated Stable Diffusion 1.5 as their first generative AI model and ran custom LoRA fine-tunes on H100/H200 GPUs to produce brand-quality outputs nobody else in their space could match
                                      • Evolved from negative prompts to reasoning model long-form prompts, giving brands more precise creative and safety control
                                      • Built a meta-prompting pre-processing pipeline to ensure user likenesses—including non-obvious details like disabilities—are accurately represented in generated images
                                      • Designed an experiential marketing platform that lets brands "world build" at conferences, trade shows, and live events by bringing fans into branded creative worlds
                                      • Added participatory user inputs through Mad Lib-style prompts and prompt injection, turning photo experiences into co-creation moments between brands and their audiences
                                      • Used Claude Code and Codex to build and ship features rapidly as a small bootstrap team, and developed a four-pillar agent orchestration framework: context, tools, verification, and workflows
                                      • Are building customer-facing "vibe coding" using the Claude Agent SDK so brands can configure and create experiences themselves within Snapbar's platform
                                      • Resources & Links

                                        • Snapbar — AI photo booth and experiential marketing platform
                                        • Patrick Ellis on YouTube — Patrick's channel on AI engineering and agent orchestration
                                        • Sam Eitzen on LinkedIn — Follow Sam for experiential marketing insights
                                        • Claude Code — The AI coding tool Patrick and Teresa both use heavily
                                        • Stable Diffusion — One of the generative image models in the mix Snapbar evaluates for its AI photo experiences
                                        • Black Forest Labs / Flux — Another model family Snapbar tests and can route activations to, depending on the creative style needed
                                        • Chapters

                                          00:00 Meet the SnapBar Team

                                          00:59 From Photo Booth Side Hustle
                                          02:31 Pandemic Pivot to Virtual
                                          08:06 What AI Photo Booth Does
                                          11:03 Why It Works at Events
                                          13:15 When AI Entered the Product
                                          14:26 Early GenAI Tech Stack
                                          17:43 Patrick’s Learning Path
                                          20:44 Why They Bet on AI
                                          28:25 Building with Necessity
                                          34:25 Applied AI Beats Models
                                          36:01 Prompting Got Easier
                                          37:53 Arcades to Home Shift
                                          38:58 Commoditization vs Application Layer
                                          40:58 Experiential Platform Overview
                                          42:33 World Cup Activation Examples
                                          45:34 QR Flow and WebRTC
                                          47:51 Capture to Display Pipeline
                                          49:24 Dark Factory and Vibe Coding
                                          55:38 Brand Safety Prompting
                                          01:00:23 Meta Prompting and Representation
                                          01:03:22 Experiential Marketing Momentum
                                          01:06:12 Agent Orchestration Framework
                                          01:10:02 Claude Code and Fable Rant
                                          01:12:48 Wrap Up and Where to Find Them

                                          1 hr 15 min
                                        • Is This Okay? How Override Labs Built a Safety-First AI Consent Coach for Teen Boys

                                          Guests

                                          • Priya Nakra, Founder and Product Lead, Override Labs
                                          • Olivia Rowley, AI Advisor and Board Member, Override Labs
                                          • In this episode

                                            • Why Priya left a 10-year tech career to found a nonprofit focused on gender-based violence prevention
                                            • How scraping 2,000 Reddit posts per subreddit validated demand for a consent reflection tool
                                            • Why Override Labs defined a "South star" — the worst-case outcome — and designed the product to avoid it
                                            • How a licensed therapist and positive masculinity coaches shaped the product's tone and eval rubric
                                            • Why the product never gives a "green flag" response — and what it offers instead
                                            • How risk classification runs deterministically before Claude is ever called, then tailors the response by tier
                                            • The three-part response structure grounded in motivational interviewing: validate, reflect, invite reflection
                                            • Why "privacy by design" meant no accounts, no cookies, no cross-session tracking — and how that became a feature
                                            • The challenge of measuring prevention when success means something didn't happen
                                            • How Override Labs is building a product ecosystem: a women's tool, a web game as a top-of-funnel, and a future institutional API layer
                                            • Resources & Links

                                              • Override Labs — Building technology to prevent harm from gender-based violence
                                              • The Fund to Prevent Sexual Assault — The philanthropic incubator that funded Override Labs' first cohort
                                              • You can find Override Lab's products here:

                                                • Is this okay?
                                                • Game Boi
                                                • Chapters

                                                  00:00 Meet Priya and Olivia

                                                  00:50 Why Override Labs Exists
                                                  02:11 From Tech to Mission
                                                  04:51 Is Technology Good
                                                  07:49 Narrowing to Teen Consent
                                                  11:07 Researching Teen Scenarios
                                                  14:33 Clinical Guidance and Tone
                                                  16:48 Designing for Reflection
                                                  20:51 Prototype to Product Flow
                                                  24:46 Risk Tiers and Evals
                                                  28:10 Defining the Conversation Goal
                                                  29:35 Motivational Interviewing Framework
                                                  31:37 Measuring Real World Impact
                                                  35:39 Privacy First Data Practices
                                                  40:29 Reaching Teens With Ads
                                                  41:56 Web Game Funnel Strategy
                                                  44:30 Funding and Institutional Pathways
                                                  46:50 UX for Sensitive Moments
                                                  49:34 Matching the Older Brother Tone
                                                  52:09 Building Safe AI for Prevention
                                                  54:35 Closing Thoughts and Thanks

                                                  56 min
                                                • Beyond Black Box Scores: How Musubi Trains Custom AI for Trust and Safety Teams

                                                  Guests

                                                  • Nikki Marinsek, Data Scientist, Musubi
                                                  • Brian McCaffrey, Software Engineer, Musubi
                                                  • Dan Means, Machine Learning Engineer, Musubi
                                                  • In this episode

                                                    • Why off-the-shelf moderation scores fail and how custom-trained models fix that
                                                    • How Musubi combines traditional ML with LLMs for different moderation tasks
                                                    • The discovery that AI can outperform human moderators—and how to communicate that to clients
                                                    • Using AI as a judge to referee disagreements between AI and human decisions
                                                    • How Musubi onboards new customers with "reverse demos"
                                                    • What custom model training actually means: fine-tuning, feature engineering, and reusable deployment pipelines
                                                    • The policy optimizer: an agentic flow that helps customers iterate on their LLM moderation policies
                                                    • Why pushing eval tools directly to customers is a core product strategy
                                                    • How Musubi is building flexible orchestration workflows for non-technical trust and safety teams
                                                    • Resources & Links

                                                      • Musubi — AI-powered trust and safety toolkit for content platforms
                                                      • Maven AI Evals Course — The course Teresa took to learn about evals (get 35% off with Teresa's affiliate link)
                                                      • Chapters

                                                        00:00 Meet the Team

                                                        01:18 Why Everyone Wears Product
                                                        02:32 What Musubi Builds
                                                        04:51 AI for Human Moderation
                                                        09:59 Adversaries and Asymmetry
                                                        11:48 Early Days and Low Latency
                                                        13:35 First Prototype Slice
                                                        15:33 Traditional ML Meets LLMs
                                                        19:52 Benchmarking Against Humans
                                                        23:09 LLM as Judge and Policy Gaps
                                                        29:53 From Prototype to Platform
                                                        31:15 Customer Onboarding Reverse Demos
                                                        36:08 Custom Models Per Customer
                                                        38:05 Fine Tuning vs Training
                                                        39:14 Embedding Driven Classification
                                                        40:04 Cost and Latency Tradeoffs
                                                        43:21 Productizing Customization
                                                        49:16 Scaling Prototypes to Production
                                                        51:58 Golden Sets and Policy Loops
                                                        56:17 Coaching Customers Safely
                                                        01:02:06 Gamified Feedback Signals
                                                        01:06:19 Agentic Toolkit Roadmap
                                                        01:09:05 Workflow Orchestration Future
                                                        01:12:06 Wrap Up and Thanks

                                                        1 hr 13 min
                                                      • Building Lorikeet: How AI Humility and a Dual-Agent Architecture Are Redefining Customer Support

                                                        Guests:

                                                        • Jamie Hall, Co-founder & CTO, Lorikeet
                                                        • Xharmagne Carandang, Product Engineer, Lorikeet
                                                        • Rona Wang, Product Engineer, Lorikeet
                                                        • In this episode:

                                                          • How Lorikeet evolved from failed ops tools to a full AI customer support concierge
                                                          • The dual-agent architecture: Concierge for customer tickets, Coach for configuration and ongoing improvement
                                                          • Why "AI humility" — defaulting to human handoff when uncertain — is a core design principle
                                                          • How Lorikeet integrates with Zendesk and Intercom instead of replacing them
                                                          • The UX evolution from workflow builder to conversational interface — and why the blank chat box is still hard
                                                          • "Resolution in the loop": how human agents unblock the AI without taking over a ticket
                                                          • Why guardrails need to be domain-specific — the cannabis company story
                                                          • How customers define their own evals and guardrails through the Coach interface
                                                          • Using AI to diagnose failure modes in traces and automatically suggest fixes
                                                          • Lorikeet's product engineering culture: every engineer asks weekly what they learned from a customer
                                                          • Resources & Links:

                                                            • Lorikeet — AI customer support concierge for enterprises in regulated industries
                                                            • Gradient Labs on Just Now Possible — another AI agent team in regulated financial services
                                                            • Neople on Just Now Possible — AI digital coworkers with a similar training-by-conversation approach
                                                            • Incident.io on Just Now Possible — AI SRE with multi-agent hypothesis investigation
                                                            • Chapters

                                                              00:00 Meet the Team

                                                              01:05 What Lorikeet Builds
                                                              02:34 Origin Story and Early Missteps
                                                              06:42 Finding the Real Support Pain
                                                              07:37 Why AI Fits Support Work
                                                              11:16 First Prototype and Early Evals
                                                              14:42 Design Partners and Selling the CLI
                                                              16:30 Product Mindset and the Real Moat
                                                              19:47 Rona Joins and Scaling Up
                                                              21:02 Milestones Voice Actions Escalation
                                                              23:48 Integrations with Zendesk Intercom
                                                              25:59 How the Agent Works Today
                                                              28:30 Coach Agent and Configuration UX
                                                              32:58 SOPs to Test Cases
                                                              34:35 Refund Flow Setup
                                                              36:12 Coach Conversational UI
                                                              38:12 Hybrid UX Guidance
                                                              40:46 Resolution in Loop
                                                              43:17 Collaboration Middle Ground
                                                              49:40 Process Maturity Limits
                                                              53:30 Confidence and Guardrails
                                                              55:59 Customer Defined Guardrails
                                                              01:01:14 Trace Diagnosis Agent
                                                              01:03:14 Product Engineers Culture
                                                              01:07:46 Closing Thoughts

                                                              1 hr 9 min
                                                            • Building Rhea's Factory: How AI-Designed Enzymes Could Finally Solve Plastic Recycling

                                                              Guests

                                                              • Arzu Sandıkçı, Co-founder & CEO, Rhea's Factory
                                                              • Mert Topcu, Co-founder, Rhea's Factory
                                                              • In this episode:

                                                                • Why only 10% of plastic gets recycled—and why mechanical and chemical methods hit a ceiling
                                                                • How enzymatic recycling breaks plastic all the way back to its original monomers, unlike traditional methods that just shorten polymer chains
                                                                • Why enzymes are selective: they can target specific plastic types even in mixed waste streams
                                                                • The discovery of a plastic-eating bacteria in Japan that opened the door to enzymatic recycling
                                                                • How AlphaFold and the Nobel Prize in Chemistry transformed what's possible in enzyme engineering
                                                                • How Rhea's Factory uses protein language models (PLMs) and multi-step AI pipelines to design novel enzymes computationally
                                                                • The evolution from a human-orchestrated pipeline to an agentic AI scientist
                                                                • How guardrails at each pipeline step keep the AI pointed in the right direction without limiting exploration
                                                                • Why wet lab data—even just hundreds of proprietary data points—can be enough to train a powerful domain-specific prediction model
                                                                • Why Mert sometimes wants the model to hallucinate (and how high temperature settings help explore the full enzyme design space)
                                                                • The business constraint: enzymatic recycling must compete economically with cheap, oil-based plastic production
                                                                • What's next: a process agent, a 5,000-ton demo plant in California, and enzymes for new plastic types
                                                                • Resources & Links

                                                                  • Rhea's Factory — Enzymatic plastic recycling technology
                                                                  • AlphaFold — DeepMind's AI system for protein structure prediction (inspiration for the Nobel Prize in Chemistry)
                                                                  • Maven AI Evals Course — The course Teresa took to learn about evals (35% off with Teresa's affiliate link)
                                                                  • Chapters

                                                                    00:00 Meet the Founders

                                                                    01:50 Why Plastic Circularity
                                                                    03:19 Mechanical vs True Recycling
                                                                    04:52 Biology as the New Tool
                                                                    07:20 Necklace and Pearls Analogy
                                                                    13:22 Low Energy Reactor Process
                                                                    17:33 Origin Story and PET Enzyme
                                                                    22:52 Protein Folding and AlphaFold
                                                                    28:32 AI Designed Enzymes
                                                                    34:28 Protein Language Models Stack
                                                                    37:14 Multi Step Protein Generation
                                                                    39:00 Building on Foundation Models
                                                                    40:50 Lab First Success Metrics
                                                                    43:10 From Human to Agentic Orchestration
                                                                    43:59 Problem Statements as Inputs
                                                                    46:18 Guardrails at Every Stage
                                                                    47:48 Prediction Models and Data Limits
                                                                    50:03 Industrial Reality and Cost
                                                                    52:30 Agentic Parallels and Orchestrators
                                                                    57:45 Impact on Timelines and Diversity
                                                                    01:03:23 When Hallucination Helps
                                                                    01:04:09 Scaling Up and Process Agents
                                                                    01:06:56 Enzyme Blends for Mixed Plastics
                                                                    01:07:49 Why Clamshells Aren't Recyclable
                                                                    01:09:34 Closing Thoughts and Thanks

                                                                    1 hr 11 min
                                                                  • Building AI Employees for Hospitality: How AITropos Takes Orders Where Customers Already Are

                                                                    Guests

                                                                    • Santi Marchiori, CEO, AITropos
                                                                    • Juan Haedo, CTO, AITropos
                                                                    • You'll hear how they

                                                                      • Spent two years exploring hundreds of startup ideas before finding the specific niche of AI-powered order taking in hospitality
                                                                      • Went through three product iterations — hardware for waiters, a waiter app, and finally a customer-facing WhatsApp agent — before landing on the right form factor
                                                                      • Identified order item identification accuracy as their single most important KPI
                                                                      • Chose a tools-based agent architecture over MCP or pipelines to hit real-time response speed requirements
                                                                      • Built a parallelized pipeline that searches for multiple products simultaneously and pre-fetches product context before the agent even calls a tool
                                                                      • Use smaller, fast sub-agents to build an "immediate system prompt" that injects relevant data into each turn without extra tool calls
                                                                      • Test with thousands of agent-simulated customer conversations run overnight before deploying to new venues
                                                                      • Reduced new customer onboarding from three months to a few weeks — and continue to shrink it as they build domain templates
                                                                      • Resources & Links

                                                                        • AITropos
                                                                        • Chapters:

                                                                          00:00 Meet the Founders
                                                                          00:59 What Tropos Builds
                                                                          01:51 AI vs Human Touch
                                                                          06:17 Restaurant Use Cases
                                                                          08:16 Why Hospitality
                                                                          10:47 Finding the Wedge
                                                                          16:00 Early Prototypes
                                                                          16:46 Hard Parts of Ordering
                                                                          18:03 Speed and Channels
                                                                          21:15 Iteration and Model Jumps
                                                                          30:50 Customer Order Flow
                                                                          35:48 Menu Discovery Question
                                                                          36:07 Menus Inside WhatsApp
                                                                          36:50 Finding the Chat Entry
                                                                          37:37 Why Text Ordering Wins
                                                                          38:30 Under the Hood Pipeline
                                                                          40:54 Tools Over Workflows
                                                                          45:05 Tooling and Prompt Composer
                                                                          49:29 Preloading Context Fast
                                                                          54:02 Founder Learning Mindset
                                                                          57:21 Evaluating Order Accuracy
                                                                          01:00:03 Testing and Human Takeover
                                                                          01:03:56 Onboarding and Scaling Up
                                                                          01:06:10 Whats Next and Wrap

                                                                          1 hr 8 min

                                                                        About Just Now Possible

                                                                        From the publisher's feed

                                                                        How AI products come to life—straight from the builders themselves. In each episode, we dive deep into how teams spotted a customer problem, experimented with AI, prototyped solutions, and shipped…