Neuroscientist Dr. Jonathan Cachat and host Brian Gallagher look at the blistering report by Jane Babin released in August 2018: “FDA Fails to Follow the Science on Kratom” (PDF available here https://t.co/G76TVsWdLY?amp=1 ). Babin demonstrates how FDA manipulated data to create a Schedule I justification based on what a former HHS Assistant Secretary of Health …

Journal Club #19: The FDA’s Bad Science on Kratom Read More »

David Oakley is a stand up comedian from Atlanta. Previously addicted to heroin, Dave discovered kratom and it changed his life. He became active in kratom advocacy and attended the historic protest in Washington, DC in 2016 that helped keep kratom legal. Later, Dave began a career in stand-up comedy and moved to the small …

51. Heroin, Kratom, and Comedy with David Oakley Read More »

In a departure from kratom science, Dr. Cachat and Brian look at a paper by a pioneering pharmacologist and researcher in the field of psychedelics, Dr. David E. Nichols. Dr. Nichols methodically lays out his case for why endogenous DMT produced in the pineal gland, brain, or other parts of the human body is not …

Journal Club #18: Pineal Gland and DMT Facts and Myth Read More »

Brian welcomes Julia Brose, graduate student at Michigan State University and lead author of the study “The Mitragyna speciosa (Kratom) Genome: A resource for data-mining potent pharmaceuticals that impact human health”. She’s joined by Dr. Robin Buell, MSU Distinguished Professor of Plant Biology, who co-authored the study. We talk about the Rubiaceae family of plants, …

50. The Kratom Genome with Julia Brose and Dr. Robin Buell Read More »

The subject of episode 17 of Kratom Science Journal Club Dr. Jon Cachat and Brian Gallagher talk about an article from Portuguese scientists about “new” psychoactive substances of natural origin, some of which have been consumed responsibly for centuries, some of which are best used if you want to murder someone via poisoning them. Oh, …

Journal Club #17: Psychoactive plants in your backyard and around the world Read More »

Shane Mauss is a stand up comedian who has appeared on Late Night with Conan O’Brien, Jimmy Kimmel Live, The Joe Rogan Experience, WTF with Marc Maron, Comedy Central, The Green Room with Paul Provenza, and Getting Doug with High, just to name a few. For the past 7 years he’s interviewed scientists on a …

49. Comedian Shane Mauss Talks Science Podcasting and Kratom Read More »

Take the new anonymous kratom survey! tinyurl.com/kratomteasurvey Hamilton Morris, creator of Hamilton’s Pharmacopeia, and producer Soren Shade talk to University of Florida scientist and past Kratom Science Podcast guest Dr. Oliver Grundmann about his new anonymous research survey on kratom tea. All kratom consumers are invited to participate. Plus, how an overly positive kratom narrative …

Hamilton Morris, Soren Shade, and Dr. Oliver Grundmann Talk Kratom and a New Survey Read More »

Andrew Tait from Vancouver BC Canada got his PhD in chemistry at the University of British Columbia and founded Tait Labs in 2011. He studied traditional Chinese medicine and “realized a need to apply scientific rigor to traditional medicines in order prove their potency, safety and efficacy in the treatment of a wide range of …

48. Plant Medicine from Food Waste with Andrew Tait Read More »

Soren Shade grew up in the woods of West Virginia. Through a program for low-income, high-achieving students, he studied philosophy at Columbia University in New York. In his senior year he worked research assistant for Hamilton Morris and ended up as a producer on Season 3 of Hamilton’s Pharmacopeia, released earlier this year. Soren is …

47. Take it as a Tea with Hamilton’s Pharmacopeia Producer Soren Shade Read More »

Another study from University of Florida is the “first report that has simultaneously evaluated the systemic exposure of 11 kratom alkaloids following the administration of traditional and commercial kratom products” (Kamble, 2021). Researchers looked at the pharmacokinectics (how drugs move through the body and are metabolized) of alkaloids in rat plasma following the oral administration …

Journal Club #16: Bioanalysis of 11 Alkaloids in Kratom Tea vs. Commercial Extract Read More »