Kratom Science

Soren Shade visits Brian in Pittsburgh bearing gifts: mature kratom leaves and a kratom plant the Top Tree Herbs greenhouse in West Virginia. This is the 2nd time the Hamilton’s Pharmacopeia producer and kratom entrepreneur has been on the podcast – the first time being #47. Brian chews kratom for the first time, and we …

63. Chewing Kratom Leaves with Soren Shade Read More »

Dr. JC and Brian look at a study out of University of Science, Malaysia. The comprehensive and detailed study in mice from University of Science, Malaysia revealed mitragynine in very high doses is an agonist (binds to and activates) cannabinoid receptor Type 1 (CB1). Mice administered with high-dose mitragynine demonstrated similar reward-seeking behavior and cognitive …

Journal Club #26: High Dose Mitragynine Causes Cognitive Impairment in Mice Read More »

Dr. Fabian Pitter Steinmetz is a senior toxicologist from Germany and an outspoken advocate for harm reduction and science-based, rational drug policy. On October 11, 2021, representing the European Coalition for Just and Effective Drug Policies, Dr. Steinmetz testified against kratom prohibition for the World Health Organization’s 44th Expert Committee on Drug Dependence . Dr. …

62. Dr. Fabian Pitter Steinmetz, Toxicologist Who Testified at the WHO Hearing on Kratom Read More »

Dr. Jon Cachat and host Brian Gallagher look at a study that examined dopamine levels with an electrochemical sensor in rats administered with various levels of mitragynine. Dopamine release was detected as significant levels after a high dose of mitragynine after 4 days. Questions explored in this episode include: Does this accurately measure the kratom …

Journal Club #25: Dopamine Response to Mitragynine in Rats Read More »

PSYCHOACTIVE with Ethan Nadelmann https://cms.megaphone.fm/channel/psychoactive?selected=HSW1919502170My guest is one of the major critics of the War on Drugs and an advocate for science-based harm reduction policy. He is founder of the Drug Policy Alliance, an organization that’s been instrumental in marijuana legalization, and helped solicit comments for the 2016 fight to keep kratom legal, among other …

61. Ethan Nadelmann, Drug Policy Alliance Founder and Host of “PSYCHOACTIVE” Read More »

Mr. Boston, who chooses to remain anonymous, was pushed out of a tree at the age of 13 where he got a slipped disk and went on a regimen of gradually stronger and stronger opioids. Living with chronic pain, he later developed an even more painful autoimmune disorder, which he says feels like being attacked …

60. Mr. Boston on Surviving 3 Near Death Experiences, Chronic Pain, and Multiple Sclerosis Read More »

Dr. Lance McMahon is Chair of the Department of Pharmacodynamics at University of Florida College of Pharmacy, a college that has been at the forefront of kratom research. Dr. McMahon studies the mechanism of action of the multiple kratom alkaloids and how they function alone and in concert on our various brain receptors. His lab …

59. Dr. Lance McMahon, Chair of University of Florida College of Pharmacy Dept of Pharmacodynamics Read More »

Dr. Jonathan Cachat and host Brian Gallagher look at a case report of a supposed kratom-induced psychosis out of a student team from West Virginia University School of Medicine Department of Psychiatry, advised by MDs Alexander Muacevic and John R Adler. A 43 year old man combat veteran with six tours of duty, traumatic brain …

Journal Club #24: Kratom-Induced Psychosis? A Case Report Read More »

Maia Szalavitz is a journalist and New York Times bestselling author who has written about drugs, addiction, and neuroscience for 30 years. Today she talks with host Brian Gallagher about her new book, Undoing Drugs: The Untold Story of Harm Reduction and the Future of Addiction, why drug policy has failed, how policy based on …

58. New York Times Bestselling Author Maia Szalavitz on harm reduction, addiction, and her new book “Undoing Drugs” Read More »

Transcript available here https://www.kratomscience.com/2021/08/12/transcript-of-kratom-science-podcast-57-representatives-of-pphi-indonesian-farmers-co-op/ This episode is a result of an interview I conducted with members of the Horticulture Entrepreneurship Association of Indonesia (PPHI). Brian speaks to Mr. Fadli Ashari, translator for Mr. Suhairi Ery, Daily Chairman of PPHI and Mr. Jamaluddin Junaid, one of PPHI’s kratom farmers. Because of translation issues, we agreed on …

57. Representatives of PPHI, the Indonesian Farmers’ Co-Op Read More »