The Thorne Podcast

Let’s Methylate: All About the Methyl Cycle


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Every cell in the body carries out a process called methylation, which plays a role in cellular energy production, hormone balance, detoxification, even gene expression. Dr. Amanda Frick and Dr. Jennifer Greer explain the methyl cycle, folate vs. folic acid, and methylated vitamins. Get answers to your questions about methylation.

Rundown

During this episode you’ll learn about:

  1. Weekly Wellness Tip: How to supplement accurately with folate and B12 [1:22]
  2. What is methylation? [2:59]
    • Methylated vitamins that support the methyl cycle [4:56]
    • Folate for pregnancy: How healthy methylation promotes reproductive health [6:27]
    • Methylation for mood support [8:35]
      • Homocysteine: A balancing act with methyl groups [10:04]
      • Effective ways to support healthy methylation with foods high in folate [11:12]
        • Lifestyle interventions to promote healthy methylation [14:47]
        • Questions from the community
          • What is the MTHFR gene and how does it affect methylation? [17:26]
          • What’s the difference between folic acid, folate, and 5-MTHF? [19:13]
          • Is folic acid only for pregnant women? How is healthy methylation different for men? [21:32]
          • Can you over-methylate? Are there any side effects? [22:28]
          • Resources to topics mentioned in this episode:

            What is Methylation and Why Is It Important?

            5-MTHF: The Best Folate Supplement to Support Methylation

            How Does Methylation Affect Fertility?

             Methyl-Guard® for Optimal Methylation

            Why It's Important to Methylate While Taking Nicotinamide Riboside

            Three Reasons to Pair a Methyl Donor with Nicotinamide Riboside

            8 Common Biomarkers to Check if You Are Concerned About Brain Health

            Folate vs Folic Acid: Is There a Difference?

            Benefits of B Vitamins

            Products related to this episode: 5-MTHF, Vitamin B12 (Methylcobalamin), B-Complex #12, Basic Prenatal, Methyl-Guard Plus®, Ginseng Plus

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