Jamie Hartmann-Boyce and Nicola Lindson discuss emerging evidence in e-cigarette research and talk about the findings of their newly published Cochrane review of interventions for quitting vaping. Associate Professor Jamie Hartmann-Boyce and Associate Professor Nicola Lindson discuss the new evidence in e-cigarette research. Jamie and Nicola share the findings of their new Cochrane review of interventions for quitting vaping published in January 2025 and funded by Cancer Research UK (https://doi.org/10.1002/14651858.CD016058.pub2). This new review included nine studies in just over 5,000 participants. Studies tested nicotine replacement therapy, cytisine, varenicline, nicotine/vaping reduction and text message-based interventions. The review found that text-message-based interventions may help young people to stop vaping and that varenicline may help people to stop vaping when compared to no or minimal support. There was some promising evidence from a shorter study of cytisine. More information is needed on other interventions, on potential harms and on the effect on use of tobacco cigarettes. Twenty ongoing studies looking at a range of interventions were identified in the review. The motivation for the review and the press coverage is also discussed.

This podcast is a companion to the electronic cigarettes Cochrane living systematic review and Interventions for quitting vaping review and shares the evidence from the monthly searches.

Our literature searches for the EC for smoking cessation review carried out on 1st December and 1st January found 3 new studies (Kale 2024 DOI 10.1101/2024.09.13.24313612; Pericot-Valverde 2024 DOI 10.1093/ntr/ntae260; Sifat 2024 DOI 10.1016/j.dadr.2024.100295) and 3 linked studies (DOIs 10.1016/j.heliyon.2024.e39695; 10.1111/add.16698; 10.1093/ntr/ntae223)

For further details see our webpage under 'Monthly search findings':

https://www.cebm.ox.ac.uk/research/electronic-cigarettes-for-smoking-cessation-cochrane-living-systematic-review-1

For more information on the full Cochrane review of E-cigarettes for smoking cessation updated in January 2024 see: https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD010216.pub8/full

For more information on the full Cochrane review of Interventions for quitting vaping published in January 2025 see: https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD016058.pub2/full

This podcast is supported by Cancer Research UK.