Jamie Hartmann-Boyce and Nicola Lindson discuss emerging evidence in e-cigarette research and interview Elly Leavens, University of Kansas Medical Center, USA. Associate Professor Jamie Hartmann-Boyce and Associate Professor Nicola Lindson discuss the new evidence in e-cigarette research and interview Dr. Elly Leavens, Assistant Professor in the Department of Population Health at the University of Kansas Medical Center.

In the November 2025 podcast Elly Leavens talks about her recent pilot trial published in Frontiers in Public Health, called 'E-cigarette puff topography instruction to enhance switching among COPD patients who smoke'. This pilot study was supported by funds from the Cancer Prevention and Control Program within the University of Kansas Cancer Center, as well as by the National Cancer Institute. The 46 participants who smoked and had chronic obstructive pulmonary disease (COPD) completed a 12-week e-cigarette switching trial in which they were randomized to brief advice or low intensity, or high-intensity puffing topography training. Elly Leavens and colleagues found that e-cigarettes had potential to minimize harm in COPD patients who smoke, but that, puff topography training did not change switch success or reduction in cigarette smoking as compared to the brief advice to switch.

This podcast is a companion to the electronic cigarettes Cochrane living systematic review and Interventions for quitting vaping review and shares the evidence from the monthly searches.

Our searches for the EC for smoking cessation review carried out on 1st November 2025 found: 1 new study (10.1037/adb0001100); 2 ongoing new studies (NCT07172438; NCT07202039); and 1 linked report reported in this podcast (10.3389/fpubh.2025.1664400).

Our search for our interventions for quitting vaping review carried out 1st November 2025 found: 1 new ongoing study (NCT07207850).

For further details see our webpage under 'Monthly search findings':

https://www.cebm.ox.ac.uk/research/electronic-cigarettes-for-smoking-cessation-cochrane-living-systematic-review-1

For more information on the full Cochrane review of E-cigarettes for smoking cessation updated in January 2025 see: https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD010216.pub10/full

For more information on the full Cochrane review of Interventions for quitting vaping published in January 2025 see: https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD016058.pub3/full

This podcast is supported by Cancer Research UK.