Let's Talk Micro kicks off 2025 with a great new episode. This time Luis is Joined by Dr. Sam Aitken to talk about sulopenem. Have you heard about this oral antibiotic? It was approved by the Food and Drug Administration (FDA) for the use of uncomplicated urinary tract infections (uUTIs). This is an oral penem, and the news of its release has caused different reactions in social media by members of the Microbiology/Infectious Diseases community. What is sulopenem? Why is it combined with probenecid (Orlynvah)? What are the concerns regarding sulopenem? When are carbapenems appropriate for treatment? Tune in for a great episode .

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Working in the microbiology field you might be familiar with outbreaks and health care associated infections (HAI). What about linens in health care? What outbreaks have been associated with health care linens (HCLs)? Are there any regulations regarding their use? What about the MOULD study? Luis is joined by Dr. Alex Sundermann to talk about HCLs, regulations, mold-associated outbreaks, and more.

Link to Dr. Sundermann's article:

https://www.infectioncontroltoday.com/view/health-care-linens-underrecognized-risk-infection-prevention-control

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Following the episode with Dr. Kelli Maddock, Luis decided to talk about his favorite organism: Pasteurella! This time Luis goes into more detail. What are some species of Pasteurella? Which animals are they found on? Which species are isolated from humans? This episode also covers media, biochemicals, diseases, and more.

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Luis and Andrea are back to talk antibiotics! This time they are joined by David Allen, an infectious diseases (ID) pharmacist to talk about another class : oxazolidinones. How familiar are you with this class? Have you performed testing on linezolid in the lab? Then you might be somewhat familiar. What is the mechanism of action? Intrinsic resistance? What organisms does this class have activity against? Tune in to find out.

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A Pasteurella multocida episode! In this episode Luis is joined by Dr. Kelli Maddock to talk about P. multocida. Kelli was a previous guest and this time returns to talk about the capsular types of P. multocida. What are these types? What diseases are associated with them? What about hemorrhagic septicemia? Kelli also talks about a model developed to look for hemorrhagic septicemia types of P. multocida using MALDI-TOF MS. Don't miss out on a great episode!

Link to Dr. Maddock's article: https://www.sciencedirect.com/science/article/pii/S0167701224001799?via%3Dihub

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As a new microbiologist sometimes terms like beta-lactams, beta-lactamases, or penicillin-binding proteins (PBPs) can be confusing. Are you familiar with the New-Delhi metallo-beta-lactamase (NDM) and its variants? How many are there? How does this enzyme affect beta-lactam drugs?How about NDM-5? In this episode Luis is joined by Dr. Raneem Pallotta, an infectious diseases pharmacist. In the episode we go over these terms. Dr. Pallotta also talks about an NDM-producing E. coli that harbors PBP3 variants. How do these variants affect beta-lactam antibiotics? Tune in for a great episode.

Link to Dr. Pallotta's article: https://www.contagionlive.com/view/ndm-producing-e-coli-harboring-pbp-insert-variants-emerges-as-new-threat

Link to other articles:

https://bmcmicrobiol.biomedcentral.com/articles/10.1186/s12866-017-1012-8

https://pmc.ncbi.nlm.nih.gov/articles/PMC5527577/

https://pubmed.ncbi.nlm.nih.gov/34800710/

https://pubmed.ncbi.nlm.nih.gov/32040179/

https://pubmed.ncbi.nlm.nih.gov/25634992/

https://www.idsociety.org/practice-guideline/amr-guidance/

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En este episodio en español, Luis conversa con la Dra. Verónica Seija. La Dra. Seija es especialista en microbiología y tiene un blog, redes sociales y un podcast donde habla sobre microbiología bajo el nombre MicroClinUY. ¿ Qué motivó a la Dra. a comenzar a hablar sobre microbiología? ¿Qué tipo de contenido encontramos en sus redes sociales y el podcast? ¿Dónde encuentran el podcast? Sintonizen y no se pierdan de una gran conversación.

Enlace al podcast: https://www.microclin.uy/podcast

Enlace a la página web de MicroClinUy: https://www.microclin.uy

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Luis and Andrea return with a new episode of the AMR series. This time, they are joined by Dr. Nikunj Vyas, and they go over glycopeptides. Whether you are a microbiologist, provider or an ID pharmacist, you are familiar with vancomycin. What is the mechanism of action of glycopeptides? Is there intrinsic resistance? How does a difference in minimum inhibitory concentration (MIC) affect treatment? Tune in to learn more.

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Throwback to a great episode! Have you worked in a veterinary laboratory? What kind of training do you need? Are you able to work in one as an MLS? Have you thought about what a culture from a veterinary specimen might look like? How do you work those up? What about antimicrobials and guidelines? Kelli Maddock and Sarah Gefroh from the North Dakota State University Veterinary Diagnostic Laboratory join the podcast to answer these questions. They are Medical Laboratory Scientists with experience in human medicine who switched to veterinary medicine.

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One of the first episodes published and one of the most downloaded episodes. In it Luis goes over catalase and coagulase.

What are biochemicals? How are they useful in the identification of bacteria? In this episode I start going over biochemicals: catalase and coagulase, two of the most commonly used biochemicals in Clinical Microbiology.

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