This is the final episode of a series celebrating the 40th anniversary of the American Journal of Kidney Disease, an official journal of the National Kidney Foundation. AJKD is recognized worldwide as a leader in clinical nephrology content, publishing original investigations describing the latest findings related to kidney diseases, hypertension, dialysis therapies, and kidney transplantation. Join us as we discuss how the AJKD has helped bring the patient experience and patient voice to researchers and clinicians in order to enhance the quality of research ideas and improve the quality of care delivered.

Guests: Harold Feldman, MD, Dena Rifkin, MD, MS & John Ortiz

Too many kidney patients face significant barriers to accessing lifesaving care. Research shows longer, more frequent dialysis done in the home yields better kidney health outcomes and improved quality of life for patients with chronic kidney disease (CKD) and end-stage renal disease (ESRD). Yet, patients do not have equal access to this treatment option. Join us as we unpack disparities in today’s kidney disease treatment paradigm and discuss the steps, we, as nephrologists, need to take to alleviate access issues and help make the options of in-home treatment a reality for more patients.

In this episode, we are joined by a hardworking group of individuals who are passionate about advocating for patients with kidney disease. Our guests focus on the ways in which AJKD has communicated health policy updates in the last four decades and discuss key developments in kidney disease and health policy. They explain some of the current policy challenges facing the kidney disease community today. Furthermore, they discuss the future of slowing progression of CKD as well as shifting kidney replacement therapies from the default in-center hemodialysis to home dialysis and transplantation. Join us as we regenerate excitement for the future in advocacy.

Our guests include:

Miriam Godwin, the NKF Health Policy Director

Sharon Moe, Professor of Medicine in the Division of Nephrology and Hypertension at Indiana University and a Past President of the ASN

Bruce Robinson, Professor of Medicine at the University of Michigan and the Arbor Research Collaborative for Health

Dan Weiner, Associate Professor of Medicine at Tufts University School of Medicine and Editor-in-Chief of Kidney Medicine. Dan is a familiar friend of AJKD, having also served as Deputy Editor for ten years, and then as Policy Forum Editor for another five years.

Resources

• Policy Forum collection

Welcome to another episode celebrating the 40th year of the American Journal of Kidney Diseases. This episode will focus on AJKD’s education features. We are joined by Dr. Jeff Berns, the Deputy Editor of AJKD, Professor of Medicine at the University of Pennsylvania and a Past President of the National Kidney Foundation, Dr. Agnes Fogo, Editor of the Atlas of Renal Pathology and Professor of Medicine at Vanderbilt University, Dr Ashgar Rastegar, Core Curriculum Editor, and Professor of Medicine and Global Health at Yale University, and Dr. Debbie Chen, former AJKD Editorial Intern and a research fellow at the University of California at San Francisco. Our guests discuss how AJKD provides education to the nephrology workforce including those who are in training. These educational tools include the Atlas of Renal Pathology, the Core Curriculum, AJKD quizzes and blog, NephMadness and the AJKD Editorial Internship. Finally, they wrap up by sharing their favorite classic paper from AJKD, which are all linked at the bottom of this episode’s description.

Resources and links:

• Atlas of Renal Pathology

Our guest’s favorite articles:

• Pathologic Classification of Focal Segmental Glomerulosclerosis: A Working Proposal (2004) Vivette D D'Agati, Agnes B Fogo, Jan A Bruijn, and J.Charles Jennette, MD

This podcast will celebrate the 20th anniversary of the very first clinical practice guideline for CKD which included recommendations for CKD classification and staging. We are joined by Dr. Kerry Willis, Chief Scientific Officer of the NKF, Dr. Andy Levey Professor of Medicine at Tufts Medical Center and Joe Coresh, Professor of Epidemiology at Johns Hopkins School of Public Health and Mike Rocco, Chair of KDOQI and Professor of Medicine at Wake Forest Medical Center.   The original workgroup for the CKD guideline published in 2002 in AJKD was chaired by Dr. Andy Levey and Dr. Coresh from Johns Hopkins for the adult section of the guideline and by Dr. Rob Portman for the Pediatric portion. This guideline had a profound impact on the clinical care of both adults and children with kidney disease and it also was a major catalyst for CKD research. The published guideline was cited by 3,500 journal articles and now has over 20 accompanying editorials.  In 2012, the guideline was updated by the KDIGO and the classification stage was altered to include information on urine albumin excretion. But overall, the CKD staging system basically remains and in this podcast, we talk about how the guideline influenced clinical care, research and even policy.

On this episode, our guests discuss how AJKD has pursued and met objectives over the past 40 years. Specifically, we will discuss how the AJKD has not only influenced the care of patients with kidney disease but helped NKF support its mission. We will discuss how AJKD helped to shape kidney disease research and clinical care and help grow patient centered care.

We are joined by four outstanding colleagues and speakers who will share their thoughts and experiences with AJKD and its impact on clinical care, research, education, and policy. 

Guests:

1. Kerry Willis-Chief Scientific Officer of the National Kidney Foundation 

Other 40th Anniversary materials:

1. AJKD at 40: The Boston Era—Years 25-35 (2007-2016) Editorial by Daniel E. Weiner and Andrew S. Levey

Over the past year and a half, the NKF and ASN have been leading the effort to develop race-free eGFR test results while maintaining the accuracy of the test. The NKF-ASN Task Force on Reassessing the Inclusion of Race in Diagnosing Kidney Diseases has recently released its final report that recommends a new, race-free approach to estimate eGFR. In this collaborative episode with the ASN, the Task Force discusses how they approached the work and what efforts are being made to ensure the new equation is implemented as quickly as possible. Our guests, Dr. Cynthia Delgado, Dr. Lesley Inker, Dr. Joe Vassalotti and Tod Ibrahim discuss the goals of the Task Force and how the healthcare team came together to come up with a solution that better served kidney patients. They discuss the implications for patients, how clinicians and researchers can adopt these new guidelines, and what resources are available for both patients and the medical community to learn more.

Developed in accordance with the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) and recommended by the National Kidney Foundation and American Society of Nephrology Task Force Reassessing the Inclusion of Race in Diagnosing Kidney Diseases, the new app is available for free by visiting the NKF website. 

If you enjoyed this episode, please follow us on Apple Podcasts, Spotify, Podbean or wherever you listen to your podcasts. Have ideas for future episodes? Email us at [email protected] or tweet us @NKF_Nephpros. Thank you for tuning in!

Dr. Dorry Segev has recently concluded multiple studies that looked at the immune response to COVID-19 vaccination in kidney transplant recipients. In this episode, Sam Kant (our new Life as a Nephrologist co-host) and Dorry Segev discuss these pivotal studies including the process, results, and directions going forward. Lastly, they discuss breakthrough infections.

List of study’s discussed:

• Immunogenicity of a Single Dose of SARS-CoV-2 Messenger RNA Vaccine in Solid Organ Transplant Recipients

Dorry Segev, MD, PhD, is a Professor of Surgery and Epidemiology and Associate Vice Chair of Surgery at Johns Hopkins University. He has published over 650 peer-reviewed research articles, and is ranked #1 worldwide in organ transplantation expertise and influence by ExpertScape. Reflecting his contributions to health care, he was recently elected into the National Academy of Medicine. Reflecting the creativity and broad reach of his contributions, he received a prestigious Global Thinker Award from Foreign Policy Magazine and was named an Innovators of the Year by TIME Magazine. His work has directly influenced policy, including two Congressional bills (the Norwood Act for kidney exchange and the HOPE Act for HIV-to-HIV transplants), and is regularly featured in widely read media including several front-page features in the New York Times. In the context of the pandemic, Dr. Segev has shifted his research to better understanding coronavirus and its implications in solid organ transplantation.

We are bringing on a new co-host for this episode, please help us welcome Sam Kant, MD! He is a transplant nephrology fellow at Johns Hopkins University School of Medicine. He has completed nephrology fellowship at Johns Hopkins, internal medicine residency and chief residency at University of Maryland. His research interests include ANCA vasculitis, transplantation and has been a recipient of multiple awards in the realm of education. He is also the chair of the American College of Physicians Young Physician Council, co-editor of the Renal Fellow Network and editorial board member of American Society of Nephrology Kidney News. Additionally, he is a member of the planning committee for the 2022 NKF Spring Clinical Meetings. 

In this episode, we are discussing critical care nephrology, a dynamic and developing field which has seen an increase in popularity in the last decade. Our guests include a mix of junior and senior faculty, which is a testament to how this field is expanding.

Amanda Dijanic Zeidman and Michael Heung have recently authored the ACKD article “The Workforce in Critical Care Nephrology: Challenges and Opportunities”  which is the topic of this episode’s discussion. They are also joined by Jay Koyner and Javier Neyra (critical care nephrologists) and Matthew Broyles a critical care anesthesiologist.

They discuss their journeys to critical care, why anesthesiologists or nephrologists might be interested in critical care, pros of receiving critical care training, how anesthesiology has supported this subspecialty, how to support nephrologists that are interested in critical care and more! They wrap up with resources, communities, and courses for trainees and nephrologists interested in critical care. Listen in to this discussion from this great community with diverse backgrounds!

Follow them on Twitter!

Javier: @jav_neyra

Amanda: @AmandaDZeidman

Michael: @keepingitrenal

Jay: @jaykoyner

For many in the LGBTQ+ community, fear of discrimination and harassment can get in the way of seeking medical care when they are sick and can put them at increased risk of serious health problems, including kidney disease. In this episode, we discussed how to create an inclusive and affirming environment in a healthcare setting for LGBTQ+ patients such as how a provider earns trust, what qualities a gender affirming provider has, understanding patient’s identities, how you can make your dialysis units more comfortable for LGBTQ+  patients, and how HCPs can participate in advocacy. Our speakers are Dr. Dinushika Mohottige and Dr. Mitchell R. Lunn, two experts in sexual and gender minority health, as well as living kidney donor and the first openly gay elected state legislator in Pennsylvania history, Rep. Brian Sims.

In this episode, you will hear from:

Dinushika Mohottige, MD, MPH:

Dr. Mohottige is a Nephrologist and Medical Instructor in the Division of Nephrology at Duke University Hospitals. She received a B.A. in Public Policy and a Health Policy Certificate from Duke University in 2006, where she was a Robertson Scholar. She then earned an MPH in Health Behavior/Health Education from the UNC Gillings School of Global Public Health and a medical degree from the University of North Carolina at Chapel Hill School of Medicine, followed by Internal Medicine and Nephrology training at Duke University. She now works under the mentorship of Dr. Ebony Boulware and Dr. Clarissa Diamantidis to engage in patient and community-centered, inequity-focused research around the impact of socio-structural factors on kidney health and kidney transplantation.

Mitchell R. Lunn, MD, MAS, FACP, FASN:

Dr. Lunn is an Assistant Professor in the Division of Nephrology of the Department of Medicine at Stanford University School of Medicine. As an internist and nephrologist with a strong interest in technology and sexual and gender minority health, Mitch’s research is designed to characterize the health and well-being of these populations. Mitch is the co-director of PRIDEnet, a participant-powered research network of SGM people that engages SGM communities at all stages of the biomedical research process: research question generation and prioritization, study design, recruitment, participation, data analysis, and results dissemination. He currently serves on the American Society of Nephrology’s Diversity and Inclusion Committee.

PA State Representative Brian Sims:

Brian Sims is a member of the Pennsylvania House of Representatives in the 182nd district. Elected in 2012, Sims is also a lawyer and activist on LGBTQ+ civil rights. Sims is the first openly gay elected state legislator in Pennsylvania history. In January of 2020, he donated his kidney to his friend. He has been vocal about supporting organ and tissue donation. Currently, he is a candidate for Lieutenant Governor of Pennsylvania in the 2022 election.