This podcast will celebrate the 20th anniversary of the very first clinical practice guideline for CKD which included recommendations for CKD classification and staging. We are joined by Dr. Kerry Willis, Chief Scientific Officer of the NKF, Dr. Andy Levey Professor of Medicine at Tufts Medical Center and Joe Coresh, Professor of Epidemiology at Johns Hopkins School of Public Health and Mike Rocco, Chair of KDOQI and Professor of Medicine at Wake Forest Medical Center.   The original workgroup for the CKD guideline published in 2002 in AJKD was chaired by Dr. Andy Levey and Dr. Coresh from Johns Hopkins for the adult section of the guideline and by Dr. Rob Portman for the Pediatric portion. This guideline had a profound impact on the clinical care of both adults and children with kidney disease and it also was a major catalyst for CKD research. The published guideline was cited by 3,500 journal articles and now has over 20 accompanying editorials.  In 2012, the guideline was updated by the KDIGO and the classification stage was altered to include information on urine albumin excretion. But overall, the CKD staging system basically remains and in this podcast, we talk about how the guideline influenced clinical care, research and even policy.