Limitless Mindset

Magnesium Breakthrough is my favorite supplement from BiOptimizers; it contains seven different forms of Magnesium...BisglycinateChelateCitrateMalateOrotateSucrosomialTaurate

I’ll tell you some about my experiences with it and break down some of the recent science on these seven forms.

Sleep hack

After dosing Magnesium, I consistently drift off to sleep quickly and slumber profoundly. Some report that Magnesium makes them calm or drowsy; their pillows become downright irresistible. And that’s not the effect it has on me - it doesn’t make me so drowsy that I can’t read a book or finish watching a movie. I just find that I go to sleep easily when the time is right.

Purely pleasant pooping!

A major benefit of Magnesium that I’ve recently discovered: it makes me a SUPER POOPER. My morning movements are MARVELOUS if I’ve taken 2-3 capsules of Magnesium Breakthrough.

Going back to the gym, I’ve been upping my protein intake. However, one day, in front of the full-length mirror at the gym, I said to myself, “You look a little fat!” Indeed, I was bloated because I had not had a proper poop all day. That evening, my wife had prepared an even more succulent meal for my consumption. But after teasing me about plumping up a bit, she insisted that I take the full range of BiOptimizers supplements with dinner and before bed. And, I’m happy to report, I had a most satisfying poop the next morning before even a drop of coffee had passed my lips. And this pattern has been consistent; if I take Magnesium before bed, I have a great, bowel-emptying poop.

Magnesium Science Overview

In the past year alone, there have been over 1100 articles of scientific research published specifically about Magnesium and 55 human clinical trials. For each of the seven forms contained in Magnesium Breakthrough, I’ll share a recent piece of science that drew my attention...

Magnesium Bisglycinate - we all know that Vitamin D3 is pretty important for staying healthy and surviving all the microscopic nastiness after us in this world; you also probably know about D3’s cofactor, Vitamin K2. But Vitamin D has a lesser-known cofactor key to its absorption and utilization; Magnesium, as established by a recent American randomized double-blinded controlled trial.

Magnesium Chelate - A Brazilian randomized, double-blind, clinical trial of hypertensive women found that 600 milligrams improved blood pressure and endothelial function.

Magnesium Citrate - Do you ever suffer from migraines? A Swiss-Austrian systematic review suggests 600 milligrams of this form as a safe and cost efficient strategy for prevention.

Magnesium Malate - The Scottsdale Magnesium Study identifies this form plus B-vitamin cofactors as ideal for addressing the magnesium deficiencies that so many suffer from.

Magnesium Orotate - It’s a Microbiome–Gut–Brain Axis hack according to a 2022 Romanian paper

Recent studies have shown that magnesium orotate is an important nutrient and adjuvant in the modulation of the microbiome–gut–brain axis. Important coincidences were found between microbiome–gut–brain axis physiology and magnesium and orotic acid metabolic features. As such, the importance of [Magnesium Orotate] and probiotic supplementation and adjuvant therapy in dysbiosis and gut–brain axis modulation is emerging

Sucrosomial Magnesium is a special formulation that boosts bioavailability, according to an Italian double-blinded repeated crossover study in healthy subjects.

Magnesium Taurate - Another American study suggests Magnesium Taurate and fish oil for the prevention of migraines.

BiOptimizers Review

We have been using the other BiOptimizers’ products for a few months now, and the Magnesium Breakthrough is my favorite - it’s the one I’d like to have permanently in my biohacker armamentarium. With the others, it was hard to say what difference they made for me; at least, I’ve had pretty good digestion for as long as I can remember. My wife, on the other hand, has significantly less-than-delightful digestion sporadically - we were hoping that BiOptimizers would be the digestion breakthrough she needed. But after taking these supplements for a few months, there is still some room for improvement with her digestion.

Magic pill?

There are some people out there looking for a magic pill solution to their digestion issues, and that may or may not be BiOptimizers’ lineup. Before you splurge on high-end digestion supplements like these, here are a few cheaper solutions to turn to...

Eat raw coconuts - This is one of my top cheap Biohacks/lifehacks, which I mentioned in the 500th Limitless Mindset Podcast. Coconuts are delicious, nutritious, and very easy on digestion - if you struggle with digestion, you can replace a meal a day with a raw coconut that’s going to cost about a dollar.

Read The Plant Paradox - This is one of the best diet books I've read and is worth a read by anyone who wants to improve their digestion and health. Dr. Gundry explains why people sometimes suffer from poor health and chronic conditions even though they "eat healthily" - it has a lot to do with something you may have never even heard of: plant lectins.

You deserve delightful digestion - for more empowering diet hacks…

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Creatine is one of the most well-known health supplements. It’s often caricatured as something just for gym bros because it helps them build muscle...

But actually, it’s a veritable Mitochondrial Nootropic for all-around human awesomeness.

This article is mostly going to focus on decoding what the human studies are saying about Creatine and how this squares up with the anecdotal experiences of Biohackers online.

Biohacker Review: The Swiss Army Knife of Mitochondrial support supplements

Creatine was one of the first supplements I used out of the behemothic box I received from PureBulk.com because it’s the Swiss Army Knife of Mitochondrial support supplements. I use it as both a Nootropic and workout performance enhancer, which I’ll describe here along with summarizing the most recent science and research done on Creatine.

As a Nootropic

While I won’t call it a smart drug, it does have subtle Nootropic effects; I notice myself being a bit more energized, optimistic, and motivated after taking a few grams of Creatine in the mid-morning. I did stack it with about 800 milligrams of N-Acetyl L-Tyrosine (NALT), which enhanced the Nootropic effects and kept me alert on a few days when I was a little underslept. I did take a heart rate variability measurement with my HeartMath device on this stack and achieved a coherence score of 1.2 while working on my laptop, which is a little of an uptick over my baseline.

Creatine and the Brain

Because the brain and nervous system require such high amounts of energy , it’s logical to assume the neurological system can benefit greatly from creatine — and this is being corroborated by clinical research . A growing number of studies have found that creatine can protect the brain from neurotoxic agents and certain forms of brain injury . (2650-2652)

Mitochondrial Nootropic

Head Strong by Dave Asprey makes the case that optimizing your Mitochondria is the ultimate performance-enhancing Biohack because your Mitochondria are the fundamental energy generation mechanism that underlies everything else. From the book:

Creatine has been a workout staple for decades, but the guys in the weight room probably don’t realize that creatine works by increasing ATP production in your mitochondria. This is what gives your muscles an extra boost of energy. Creatine also benefits your brain. In one study, creatine supplements caused a significant increase in working memory and intelligence. (p. 263)

On the two-week Head Strong program, I recommend the loading phase so that you can feel the creatine’s effects right away. If you do this, be sure to drink a lot of water. (p. 264)

Vs Sleep Deprivation

A 2024 randomized trial found that a single high dose (about 0.35 g/kg) increased brain phosphocreatine and buffered the cognitive hit of overnight sleep loss.

If you’re underslept, reach for some Creatine (and don’t be shy about the dose). It assuages sleep deprivation, jet lag, stress, and fatigue generally because: “The more the brain is stressed, the more Creatine comes to rescue,” according to Dr. Candow.

Creatine stacks well with one of my long-time daily driver Nootropics: L-Tyrosine. My first year as a brand-new dad was surprisingly productive thanks to this stack (and some other lifehacks).

Workout Performance Enhancer

One of the most reliable effects of Creatine is that you’ll be able to push yourself a little harder in the gym. You’ll walk home from the gym a little sorer than usual, but with a proud smile on your face for the gains you’ve made: pushing more weight, achieving more reps, or sweating it out more doing cardio. I stack it with one of my other favorite workout performance enhancers, HMB, for epic workouts that I’d be sore from for days if it wasn’t for the recovery hacks I employ: red light therapy on my muscles, healing PEMF frequencies, and a before-bedtime massage from my lady.

The other thing I like about Creatine is the muscle pump; it does make your muscles look bigger if you take it and work out consistently. HMB has a complementary effect; it essentially preserves muscle mass if you’re slacking on your workouts. So a vain yet economically-minded Biohacker would want to use them both; take 5 grams of Creatine and HMB on workout days to build muscle, and then if you need to take a few weeks off the gym for travel, work, or over the holidays, take just a few grams of Creatine daily as a Nootropic and HMB to preserve your strength gains.

A caveat on workout performance enhancers...

As Jeff Cavaliere of ATHLEAN-X preaches, you earn the right to take workout supplements. You probably shouldn’t be cramming supplements in your mouth your first week or month in the gym - you should put in the work for a couple of months building up foundational strength and competence before turning to supplements. The kinds of performance enhancers I name here do unlock an extra reserve of power and motivation. They can make you overconfident in the gym when you shouldn’t be, risking an injury that will ultimately set you back in your fitness.

A Muscle-Building Biohack

Ben Greenfield, in Boundless, breaks down why Creatine belongs in your bodybuilding armamentarium

With increases in exercise or muscle damage, your physiological need for creatine is increased. Research suggests that creatine supplementation can increase your muscles’ work capacity and power output while enhancing your lean body mass and physical endurance. Outside of the athletic population, creatine has been shown to reduce muscle breakdown and even to support cognitive function, especially in the elderly. Because creatine stores high-energy phosphate groups in the form of phosphocreatine, it releases energy to aid cellular function during stress. This effect causes strength increases after creatine supplementation and can also benefit the brain, bones, muscles, and liver. I recommend 5 g per day, preferably in one to three doses and mixed into warm water or another warm liquid to maximize absorption. (p.581)

History

Creatine was isolated in 1832 by Michel Eugène Chevreul from a water extract of meat. He named it from the Greek kreas, “flesh.” Justus von Liebig confirmed it as a normal constituent of muscle in 1847 and noticed that wild foxes killed in the chase had far more Creatine in their flesh than caged animals, an early hint that work and Creatine travel together.

Factoid: Performance enhancement effects were first noticed giving Creatine to a racehorse named Jolly.

Overview of Creatine Science

In the past decade, over 11,000 articles of scientific research specifically on Creatine have been published on PubMed, including over a thousand clinical trials. Let’s take a look at several of them that jumped out at me...

A Spanish study compared Morning versus Evening Intake of Creatine in Elite Female Handball Players. It concluded that while circadian rhythm certainly affects performance, it didn’t make much of a difference after 12 weeks in terms of performance and body composition. However, unless the evenings are the only time you can make it to the gym, I would only take it in my mornings or early afternoons, as it is a stimulating Nootropic that might mess with your sleep.

A Canadian-Italian study looked at the synergy of Creatine and caffeine. Gym buddies have occasionally looked at me funny when I showed up to the gym with a coffee in hand, but caffeine indisputably increases power output. And in my experience, black coffee doesn’t mess with my stomach during a workout. However, the study reports that the uptick in performance from the combination was negligible. A recent systematic review evaluated ten different studies combining the two, and the conclu…

We've got a bevy of questions here ranging from arresting cognitive decline, new dad lifehacks, and old English inquiries to Reddit randomness that we'll get to, but I have a direct ask for you: if you've gotten some transformative value from my work--this is your chance to shape it in the future--participate in the...

[This should take you less than 10 minutes to complete]

Disclaimer

What you find here is NOT medical advice. I’m not a doctor. I’m just an experienced, unlicensed self-experimenter practicing free speech by talking about my own extensive experiences and my interpretations of published science. Please see my guide on How to Biohack Smart and Safe. You should consult a doctor about any biohacking you’re doing and, ideally, also get a second opinion.

#46 Questions

Q

A 38-year-old former tunneling worker based in Sydney with a 5-month-old son, with due to deep concerns over potential early cognitive decline, citing word-finding difficulties, memory lapses, executive dysfunction, a history of shift work and fine silica dust exposure, and a APOE3/4 genotype with his mother, who has early Alzheimer’s at 66. Additionally struggling with chronic mild irritation, elevated anxiety manifested in hair-twisting habits, and persistent mild neutropenia alongside recurring skin rashes, he has already stopped past heavy partying and alcohol use and is actively managing his health through an extensive supplement regimen, 40 Hz light/sound therapy, and vagus nerve stimulation.

A

Recommndations

For mind and memory

Piracetam - The best smart drug for memory

Mnemonics Practice - Because "even average memories are remarkably powerful when used properly"

Working memory rehab protocol - for restoring brain power and focus

Add neuroplasticity stimulators: Semax, Selank, and Lion’s Mane

Stress management

Are you an MTHFRer? Do 30 minutes of meditation a day; if not, reframe as “ustress”

Parenting hacks

New dad life will mess with your cognitive powers - peaceful parenting makes life easier. 1) no vaccines 2) no yelling in the house 3) no circumcision 4) no corporal punishment 5) no daycare

For much better sleep as a new parent: alternate nights sleeping with the baby

Supervised detox protocol is a good idea - THIS is out of my wheelhouse; hire a good functional medicine doctor

Empirical Zinc protocol - detailed in my Zinc meta-analysis: Targets his persistent mild neutropenia (1.6 × 10⁹/L) and recurring skin rashes. Regulates NMDA receptors, supporting synaptic plasticity and executive function without overstimulating anxiety.

Q

Responding to Defying dire destiny: born dead, breaking world records & thriving despite cerebral palsy 🎙️ with Mikael Avatar

I was initially going to skip this podcast because I didn’t think it had anything to do with biohacking, but this truly fits the definition. The intro is excellent and I literally had to pull over from driving and delve into this. I haven’t looked to see if there’s a transcript but if not, I’ll generate one and it will be something that I reflect back on and share often. Very meaningful and life-changing which is the essence of biohacking. Thank you.

A

Not sure if I’m going to start adding transcripts -- is that something that more of my audience would like?

Q

Jonathan, random question: I see you swaying side to side in your videos: do you have restless leg syndrome by chance? Or perhaps just have excessive energy during peak energy parts of the day?I sometimes do the bobbing knee when sitting, and sometimes when having insomnia, I find that if I shake my legs it helps my muscles to relax, so perhaps I have it somewhat myself.

A

Recommndations

Sitting is the new smoking, so I have long used an adjustable laptop stand - the poor man’s standing desk.

Do Soleus Push-Ups

Q

I vaguely recall from the years when i was more nootropics obsessed that some biohackers had started to consider racetam nootropics as having some higher risks/more moderate side effects, and thought folks were more moving away from them? Am I mistaken in this?

A

Racetams are one of the safest classes of Nootropics. Consider the safety evidence for the Racetam-rich stack I created, Caballo.

Q

Picture two identical twins over the next decade: twin A takes the absolute gold-standard nootropic stack every morning but lives in total behavioral chaos, while twin B takes sugar placebo pills but maintains absolute stoic discipline and laser focus. Who wins in the long term ??????

A

The one taking the placebo, of course! Might this hypothetical question be referring to the fictional Biohacker twins in my novel series Hourglass?

Q

A subscriber forwarded an email from David Tomen (Nootropics Expert) warning about a 2021 Seoul National University Hospital study where +100,000 Alpha-GPC users aged 50+ showed a 46% higher relative stroke risk compared to over 11 million non-users—with the risk increasing in a dose-dependent manner among those taking it daily for up to 10 years—leading Tomen to label it one of the “most dangerous supplements.” Will Alpha GPC KILL biohackers?

A

Association of L-α Glycerylphosphorylcholine With Subsequent Stroke Risk After 10 Years - The study highlights that long-term, high-dose Alpha-GPC use in elderly populations with existing vascular vulnerabilities carries potential cardiovascular trade-offs. However, claiming it is “one of the most dangerous supplements on the market” for a healthy adult using moderate doses is classic headline alarmism.

Recommndations

CDP Choline (Citicoline) - Alpha GPC alternatives like Citicoline follow a different metabolic pathway and generally do not raise TMAO levels to the same degree.

Q

What manner of bodily rite or daily custom, seeming on the scroll as dry and unlovely as a plunge into icy waters or the blocking of the blue light, yet in the secret chambers of the home, brings forth the most wondrous and desirable fruit? As it is written, “The glory of young men is their strength, but the beauty of old men is the gray hair,” yet here the true glory lies in the unseen work.

A

Recommndations

Tantric practice is one of the awesomest ethical hedonism hacks--watch the first module of the course, 9 Steps to Becoming a Tantric Man

Q

What should I do with 40 cans of oysters?Guys and ladies, I made a small blunder (long story) and ended up with 40 cans of oysters — Crown Prince Natural, Whole Oysters, Packed In Water, 8 oz (226 g) ordered from iHerb.Ideally, I want to sell them to get my money back... but where? If that doesn’t work out, or if you have good suggestions, I could also donate them somewhere... but where??Give me ideas on what to do with them.

A

Recommndations

Start a career/hobby as an “oyster cook” vlogger or “oyster influencer”

Prepping supply of oysters (for the Zinc!)

Your questions inspired this catchy Limitless song...

INVEST at least $300 in your own mind with these recommended sources and get a Biohacking consultation

Lean Life Coaching biohacking consulting

As mentioned in the podcast, this is a very lean biohacking consulting/life coaching program. Here’s how this would work...

* The Biohacking Consultation is 1 hour and 45 minutes total - which is actually two consulting calls.

* First Call 1 hour - Discovery & Strategizing call, I need to ask you some questions, we’ll discuss your history, and outline a biohacking strategy and action plan to overcome your issues.

* Second Call 45 minutes - Follow-up call in 30 or 60 days to see how you’re doing with the plan we outlined; how you’ve improved, what you’re struggling with, etc

There are a few important reasons we split the time up into two calls

* It’s a significant motivation hack for you to follow through on the biohacking habits and plan we’ll outline because you’re accountable to me in 30 or 60 days.

* I’m incentivized to come up with a really effective biohacking strategy for you because I have to talk to you after you’ve been following it for a month or two.

* It timeboxes us with a deadline of 30 or 60 days for you to make improvements and accomplish your goals.

Your skin is in the game here, that yo…

I’ve been fasting for years; in fact, it’s a major economic lifehack, so I decided to read Dave Asprey’s recent deep-dive book on the topic, Fast This Way. The book is a bit of a memoir, actually; it’s punctuated by vignettes from a grueling (and transformative) 4-day fast that the author did alone in a cave in the Arizona desert.

Why does fasting work?

How can fasting do so many good things for you? The answer is simple: your body is already packed full of repair and rejuvenation mechanisms. Thousands of years—no, millions of years—no, billions of years of evolution have shaped them inside of us. Your ancestors have run the gauntlet of death and extinction. You and I are the survivors of an inconceivably brutal winnowing process. We wouldn’t be here if we didn’t have all of those health-preserving cells and molecules. All that fasting does is remove the dietary impediments we put in our own way and allows us to take maximal advantage of the gifts evolution has given us. Fasting puts us in control of a 4-billion-year-old evolutionary process. (pp. 97-98)

there’s a fundamental difference between hunger and craving. Hunger is a biological message, and it is something that you can control. Craving is a psychological psychological need, and it is something that tries to control you. The truth is, you can go a long time without eating, and you won’t suffer for it. In fact, you will thrive. (p. 4)

Fasting is an amygdala hack

But as essential as the amygdala may be, it can also be a source of irrational, destructive fear. It’s a major contributor to that voice in your head that says you might just die if you do something you’re afraid of—such as going on a job interview, ending a bad relationship, speaking in public, or simply skipping a few meals. Intermittent fasting enables you to put the amygdala and the whole reptilian part of your brain in its place, so that you can be more fully human, more fully yourself, less burned by your fears. (p. 7)

Fasting is really the best spice!

When you end a fast from anything, it makes that substance or that experience much more appreciated. It causes heightened pleasure and brings easy gratitude into your life. (p. 13)

I’ll second this! Fasting is reliably a hedonism hack; before I eat a meal I know I’ll love, I’ll fast to multiply the pleasure.

Fasting for COVID resilience

Adrienne Barnosky, an endocrinologist at Duke University School of Medicine, and her colleagues confirmed that intermittent fasting helps prevent insulin resistance. (p. 16)

As explained in Dr. Mercola’s recent book, insulin resistance is a major risk factor that puts you in danger of a catastrophic case of the wu-flu.

Bulletproof coffee is recommended relentlessly throughout the book...

Which I don’t have a problem with; it can be a game-changer for fasting. I drink Bulletproof-style coffee almost every day, and it powers me through my intermittent fast.

Wake up in the morning and drink a cup of Bulletproof Coffee: black coffee, a dollop of grass-fed butter, and a teaspoon or more of C8 MCT oil. It’s the best latte you’ll ever drink. (p. 18)

And you don't have to buy Bulletproof products; just add butter and MCT oil to quality organic coffee, and your fast will be a whole lot less arduous.

On dieting

Are you addicted?

Two of the most common biological addictions are to wheat (gluten) and dairy products. You may think you don’t have to worry about them because you’re not allergic to either one. Truth is, you probably have no idea what effect they’re having on you. How many times have you gone three days without eating wheat or dairy protein? (Butter contains a negligible amount of protein.) Both gluten and dairy products have known inflammatory effects. (p. 48)

Fasting vs dieting

Here’s another example of the stark difference between dieting and fasting, based on an experiment I ran on myself. Ten years ago, while I was doing research for my 2014 book The Bulletproof Diet (the first big book that described ketosis with intermittent fasting), I decided to test my theory that the effects of fasting are more powerful than the effects of calorie consumption. I intentionally did everything wrong from the standpoint of the calorie-counting police. I ate a staggering 4,500 calories a day and kept doing it for a month, but for breakfast I had only Bulletproof Coffee with tons of butter to raise the number of calories in it. I cut my sleep to less than five hours a night, which triggers obesity. I stopped exercising. But I continued my program of intermittent fasting as I did all those things. By the straight, Ancel Keys–style accounting of the CICO diet, I should have gained about 20 pounds. I was hoping I’d gain only 3 pounds or so. That would have poked a big enough hole in CICO that I’d feel vindicated. The results were even more startling: I actually lost weight. I felt amazing. (p. 65)

CICO (Calories In, Calories Out) diets

The goal of diet culture is to make you feel as though a better you is just out of reach. That’s one of the many reasons why the “calories in, calories out” model, commonly abbreviated as CICO, should be relegated to the dustbin of failed science. This approach treats your body as though it’s a meat robot when in reality it’s a dynamic system that responds to calories differently based on their source, the time they’re consumed, and the unique physiological makeup of the person consuming them. Yet the myth lives on, leaving obesity, shame, and suffering in its wake. (p. 61)

The “eat small meals” myth

A great many diet plans advise you to eat every three hours to keep your metabolism humming along at warp speed so you can lose weight. If you follow that advice, the minute you hit the three-hour mark and you start feeling the slightest bit hungry, you answer the ghrelin response and eat something. If you don’t, cravings kick in, your blood sugar level starts to drop, and you yell at someone nearby because you feel like crap. (You are feeling hypogly-bitchy!) Your biggest question at three hours isn’t whether to wait a few more hours before eating but what type of calories you’ll be putting in your body for your next meal. This is a bad idea because your body never gets a break, and the constantly high blood sugar level created by constant snacking ages you. (p. 68)

Fasting is primal

The history of human evolution is also the history of food. Believe it or not, it’s the history of fasting, too. Our bodies and brains are inherently adapted to it. (p. 81)

Fasting—either with no food or with a vanishingly few calories from plants—was simply a part of our ancestors’ lifestyles. They had no choice. This habit of eating and then fasting continued for not just decades or centuries or even a few millennia; humans have lived a lifestyle of feasting and fasting for almost 290,000 years. (p. 82)

Interestingly...

The modern routine of breakfast, lunch, and dinner is less than two centuries old. (p. 85)

Starting in the early nineteenth century, with the advent of the Industrial Revolution, people in the Western world all began eating more or less on the same schedule. Before that, the concept of time wasn’t as regimented. You didn’t need to know exactly what hour of the day it was; farmers just cared about when the sun rose and set. After the Industrial Revolution, though, a pocket watch became an incredibly valuable item, because it told you when the trains were going to arrive and depart. Trains ran on precise schedules. Then factories and stores ran on precise schedules. Our new connection to time, which was driven largely by train schedules, led us to start planning our meals for specific times each day. We scheduled our food around trains, not our actual hunger or the needs of our bodies. (p. 85)

The three types of fasting

Intermittent fasting

The most workable intermittent fasting schedule for all but the most extreme is to skip breakfast, then eat lunch and dinner. It seems extravagant to call such a straightforward guideline a “biohack,” but th…

Perhaps you’re enticed by the idea of sex hacking but just a little confused about where you should dive in: taking libido-enhancing supplements, practicing tantric semen-retention techniques, or experimenting with some of the questionable tech and gadgets you’ve seen advertised. I’ll simplify things; start by taking the herb Epimedium, which also goes by the name Horny Goat Weed. What can you look forward to from it...

* Stronger, harder, longer-lasting erections. You could sort of think of it as herbal Viagra.

* Sensation enhancement; your dick is going to feel better when you give it what it wants. You’ll be a bit more sensitive but if you’re like many herbal hackers, counter-intuitively your ejaculatory control won’t totally go out the window.

* Mood enhancement: 20-30 minutes after taking enough, you’ll be taken by a bit of rowdy adolescent excitement and anticipation about the romp to come.

* Taken regularly, it will have an uplifting effect on your testosterone and male essence. You’ll be a bit more interested in the fairer sex and unapologetically masculine.

A caveat: Horny Goat Weed is not exactly herbal Viagra, and it should be used as part of a holistic manly health regimen. If you eat too much, drink too much, don’t get enough sleep, or watch too much porn, Horny Goat Weed may not save you from whiskey dick.

A romantic getaway essential

I like it so much, it’s one of the few supplements that I make space for in my luggage anytime Mrs. Roseland and I are getting out of town for a change of scenery. Recently, we celebrated our fourth anniversary in a beautiful historical town. We found a restaurant that we fell in love with where we dined daily, enjoying each other and the breathtaking view from their terrace.

And I indulged in fine food and drink a bit more than I usually do, which is often not the greatest prelude for epic sexy time. But stacking PureBulk.com’s Horny Goat Weed and Tongkat Ali, our passion burned hot (so hot that we literally started a small fire in our AirBNB - fortunately the fire brigade was not needed!)

Capsuled or powdered?

I prefer powdered as I like to take it as a hearty pre-coital tea. In my extensive experience with herbal adaptogens, the effect is a lot more acute from them when steeped in boiling water. However, as a monogamous dude, I have the privilege of usually knowing when I’m going to get laid and the time to leisurely enjoy an Epimedium tea. Single guys might want to bring a few capsules along on dates just in case things are going really well, and they’ve had a bit to drink.

Featured in Fiction

This performance enhancer made it into Hourglass, my novel about Biohacking, philosophy, and seduction...

He also needed Nicotine; in the bathroom, he discreetly took a .25 milliliter hit of USP solution from a minuscule vial. It cleared his mind yet burned in the back of his throat. I need a drink to wash this down! But I’ve already had some to drink… Tonight I close the deal with Astrid, and I’ve had some to drink - I don’t want a repeat of my floppy cock in the IR sauna! Might as well take Horny Goat Weed, too. He took a dropperful of the Epimedium tincture he’d also brought.

She took a thoughtful bite of a cracker, “Xavier, you made me feel like I was in a movie tonight - with a helicopter, the champagne, and the car - but these are not the things I care about in life. And I don’t want them if they come with guns, violence, and you going to prison for these crimes that you say are in the past…”

“I’m NOT going to prison. I’m going to solve the Goldbach conjecture, marry you, and we’re going to be free.” His certainty was supreme, buoyed by the PDE5-inhibitory mechanism of the Icariin, the active constituent of Horny Goat Weed - that made the herb live up to its name.

Purity-verified with COA

The final thing I like about PureBulk.com’s libido-enhancing supplements is that they’re verified as pure with a certificate of analysis from an accredited American lab. This evidence of purity is something you should demand that your local vitamin shop or the sellers on Amazon likely can’t provide.

Gents, for more little-known tips, tools, and tricks to take your sex life to the next level…

Support me on Substack? For $7/monthly?

“I swear upon the altar of God eternal hostility against every form of tyranny over the mind of man.”

That is the famous declarative prayer of Thomas Jefferson. You have heard it a hundred times before on podcasts; it gets repeated endlessly across the pro-freedom dissident sphere online.

But cowardice remains one of the most powerful forces in human history, and too many of the political influencers you follow and support are ultimately flaccid in the real fight for human freedom.Why? Because the pen is mightier than the sword, BUT the penis is mightier than the podcast.

Let me explain...

Cast your mind back to the early 2020s...

The height of lockdowns, mandates, media propaganda fracturing families, and state apparatuses crushing dissent with a heavy boot of censorship. Yet the technocrats severely underestimated how furiously the flame of freedom burns in the human heart. You can now get on a plane, get a job, or enter a grocery store without a vaccine passport, because of courage (the virtue that gives all other virtues their potency)--because of the courage of those who brought sharp words of truth to the globalists’ propaganda fight and the courage of all of you who simply refused to comply.

That dark chapter proved that when enough people simply say “no” and speak unvarnished truth, tyranny falters. We can score that as a battle won.

But the fight for a freer future is far from over. And truth warriors can only do so much for the fight for freedom with their words. In fact, I’d argue that we are about maxed out on the impact we can make with our words. Here’s why...

Most people don’t have minds, philosophically speaking

I’m not saying they don’t have gray matter between their ears...

The argument is that what we philosophically call a “mind” is something most people don’t actually possess: the capacity to take in sensory data about the objective world, process it rationally, construct a coherent worldview, update that worldview when new evidence arrives, and translate it into deliberate action.

Most people don’t actually do this. Most people don’t have anything approaching a coherent worldview. Their beliefs rarely update in response to new evidence. They’re largely an amalgamation of programming and indoctrination absorbed years or decades ago, driven by basal instincts and remarkably susceptible to propaganda.

That’s most people. They’ll comply when the next plandemic comes around because their “best friend”--an AI chatbot--tells them they should. There’s NO getting through to them. They are too mired in their slavery to the screen.

The next battle will not be like the last...

Those who seek to enslave us all are changing tact; bringing more seductive and insidious weapons to bear. I suspect that the globalists' plan to enslave us all is simply the slow annihilation of the kinds of genes which carry the Promethean flame of free will. Not all of us carry them equally. The globalists want the Idiocracy future. They want less of us; they want the coming generations of tax livestock who will happily accept their chains.

So how do we win?

This brings us back to Jefferson’s oath: “I swear upon the altar of God eternal hostility against every form of tyranny over the mind of man.”

The crucial word in that pledge is eternal.

Memento mori. You are going to die one day. How do you wage an eternal war?

Stop bringing mere words to a cock fight. Stop bringing mere memes to a gene fight. We’re fighting tyranny with our words, because “the pen is mightier than the sword.” But it’s time to also fight tyranny with another body part because the penis is mightier than the podcast.

There are a lot of influencers and public personalities- I was one of them- who publish a lot of content exposing and pushing back on “globalism.” And, at times, this certainly takes courage--we faced censorship that did substantial damage to our abilities to make a living. But at best, it’s a short-term strategy in the fight for a freer future.

And...

At worst, it decays into a comfortable online grift—preaching to an established choir for superchats and view counts. What once took courage can all too easily become a comfortable “lifestyle entrepreneurship.”

How much real difference will another outrage podcast or commentary video make in 10, 50, or 100 years? Practically none.

Baby-making for the win

Something that doesn’t get emphasized nearly as much as it should is the decisive role of heritable genetics in the fight for human liberty.

If Thomas Jefferson’s prayer resounds with you, that’s because your ancestors were warriors; they sharpened swords and rebelled against feudal tyrants; crossed treacherous oceans to build something freer; they stormed ships and threw tea overboard. If “declaring eternal hostility” resounds powerfully for you, you’re the kind of person who should absolutely have as many children as you can.

Podcasts, media, books, and even IRL protest movements make a difference for maybe a few years.BUT passing on your freedom-loving warrior genes--having children and raising them with love and devotion, imbuing them with your values--is almost certainly the most significant thing any of us can do for the fight for freedom. THAT makes a difference for CENTURIES.

So share this around because too many online personalities and influencers--in the broader dissident sphere of the internet--bring only their words to a fight that is futile if good men remain, not-so-metaphorically, flaccid. The pushback on the COVID tyranny was a single victory in a war stretching many millennia to determine whether or not humanity will be a slave species. And that war is not over. It demands more from us than publishing “content” at this point!

I’ll quote from my book, Hourglass, a philosophical novel...

“...the structure of an hourglass is timeless in contrast to the sand that passes through it. Your genes draw you to her shape because through it, eternity beckons. Through a woman’s beauty is the only way we can achieve genetic immortality in this world. Through her shape, we cast our essence into the future; the only way that we defeat death, practically, and become like God, metaphorically, creating new life in our own image. Your legacy, in the truest sense, is the exponential effect of your genes striving for the future. But if you fail to plunge into womanly beauty and leave a part of yourself there, then in the grand arc of history - no matter what you accomplish in this life - you will be like a spear falling from a great height into a dark pool. Your legacy, barely a ripple.”

So if you are a man with testosterone coursing in your veins, the Promethean flame burning in your chest, and the star seed of a thousand supernovas in your loins—thrust, with keen aim, into the soft places that will take it!

“I’d love to fight for freedom with penis and cast my essence into the future through the beauty of a woman, BUT I’m single, and I never meet women with whom I really see a future...”

You might be saying, at this point. Tough love, gents: You probably have met her, but you hadn’t done the right personal growth to deserve her, or you lacked the seduction skills to get her (and keep her). Perhaps I’m underestimating you, but you may lack the specific seduction skills to set up such a relationship for long-term tranquility. That’s why you need to move to the top of your reading list my 500-page book, Don’t Stick Your Dick in a Blender: How to meet a nice girl instead - from a tantric husband with a better sex life than you!

You should get the print edition (printed near you via Lulu) because this is a book worth turning your phone off for--it includes the downloadable audiobook and digital book via a QR code.

And if you’re a woman, your role in this f…

I watched a very well-produced documentary by, obviously, a very critical and thoughtful filmmaker. It certainly stimulates the spine-tingling cognitive dissonance that exploring the details of 9/11 should trigger for anyone who’s able to think for themselves.

I’ve watched (what seems like) ALL the 9/11 documentaries and WAY too many Alex Jones videos about 9/11. This has drawn me down a rabbit hole of Internet weirdness, exploring conspiracy theories about…

* JFK Assassination

* Climate Change

* Pizzagate

* The Flat Earth Theory

* The Mandela Effect

* The Nazis and the Holocaust

* The Rothschilds and Illuminati

* The Jews and Zionism

* Faked Moon Landings

* Vaccines and Big Pharma

For me at least, most of these conspiracy theories are pretty unimpressive, even though they all contain a nugget of veracity. The level of evidence for the 9/11 conspiracy is so high that the rest of the conspiracy theories are pretty underwhelming. The case for a malicious conspiracy with 9/11 is so strong that, in comparison, there are just gaping holes in the reasoning of these other conspiracy theories.

Yet after watching this most recent documentary, I come back to this question…

Why does it matter?

Let’s say “hypothetically” that…

9/11 was an inside job, traitors within our own government planted bombs in the building, all as part of a grand plot to erode American freedom, drawing us into endless wars that would ultimately usher in a New World Order where we would all serve as unwitting slaves of the Rothschilds, the Illuminati, or whoever.

What should I do about that?

They have (literally) almost all the money and military might in the world.

I’m just a 41-year-old web developer and writer. I just have my laptop, my green tea, and my coconuts.

What can I do?

If such a diabolical force exists in the world, wouldn’t my attacking it really be tantamount to a mosquito attacking a Tyrannosaurus rex?

If you are rational, you will conclude that there is not a lot that you can do about it. This is why a lot of people categorically disregard conspiracy theories — why waste the cognition on them?

Some people might say: Don’t be so defeatist! Make a website, write a book, make YouTube videos, or try to wake up people around you!

There are a lot of other, more capable people fighting the information war like…

* Alex Jones of Infowars

* Stefan Molyneux of Freedomain

* James O’Keefe/Project Veritas

* Tim Pool

* David Icke

* Mike Adams of Natural News

* Del Bigtree of The Highwire

* Luke Rudkowski of We Are Change

I’m not going to do a better job of disseminating information than these guys — who I don’t agree with on everything, but they are clearly very effective at pushing back against this statist global world order that is being imposed on us without our consent.

Instead, I think we should ask...

What is a rational response to a diabolical cabal of globalist elitists who conspire to commit terrorism, start wars, and enslave us?

I think it’s…

* To be a highly disciplined critical thinker who questions everything mainstream.

* Building a tribe both locally and on the Internet of like-minded people.

* To free oneself of wage slavery by becoming an entrepreneur.

* Biohacking with smart drugs, Adaptogens, anti-aging supplements, or longevity tools and tech.

* Make myself financially antifragile by using cryptocurrency or investing in gold.

* Avoiding toxic foods and products of bad science.

* Preparing for disaster and calamity.

* Being highly skeptical of politicians - even the ones that tell you the things you want to hear.

* Training my body to be physically robust.

* Getting into and maintaining a supportive long-term monogamous relationship.

* Healthy skepticism of institutional, entrenched power structures and establishments.

The rational response to a malevolent conspiracy is the personal development that you should be doing anyway.

Of course, 9/11 matters.

Truth matters. Justice matters. Those nearly three thousand people who lost their lives that day matter. The first responders still suffering matter. What I’m getting at in the title of this article is that I’m not sure if the conspiracy theory matters anymore. I fail to see the personal development takeaway or actionable value from conspiracy theory documentaries if I already accept that…

The government is immoral.The government is an organized criminal syndicate.The government is fundamentally structured for corruption and moral hazard.The government can and likely will spy on you.The government will always betray you.The government is in the business of inventing problems that it pretends to fix.The government should be shrunken, and its power should be limited.The government is NOT to be trusted at all.

If my friends and family accept the above, is there any reason to try to convince them that 9/11 was an inside job?

I’m pretty sure that almost everyone who could be convinced by the evidence of the 9/11 conspiracy has been. By continuing to talk about it, I’m not sure if we are doing more good than harm. I don’t think I’m going to try to red-pill people anymore with 9/11 truth.

What I will do is remind people that they don’t deserve freedom.

Freedom is not owned; it is rented, and rent is overdue.

I suspect that in the coming decades, the truth about 9/11 will bear itself out, and it will turn out that bad actors in the US government played a part. And it will be met with a collective shrug by the country and the world. People just won’t care that much. The limited investigations that the authorities will do will find that the conspiracy was limited to very few bad actors who have already passed away. The ultimate I told you so moment for millions of red-pilled 9/11 conspiracy theorists will be a Pyrrhic victory.

Changing people’s minds is notoriously hard...

Especially when it comes to political and ideological matters; however, the wake of upsetting events is actually the best time to try to red pill people. The day after the Barcelona terrorist attack, when everyone else was doing the formulaic virtue signaling with the hashtags and the flag filters, I lost some Facebook friends with this vitriolic invective…

And my own mother scolded me for not being more compassionate and sensitive to people I have casual digital acquaintances with who may have lost loved ones. I responded that it was not that long ago that I myself strolled the Ramblas in Barcelona — it could have been me run down by that truck or you.

If I lose a few Facebook friends over it, I couldn’t care less. I have real-life friends. I’m desired, cherished, and loved in real life because I’m the kind of guy who stands up for things. The best time to wake people up is when they are reeling from the cruelty of reality.

I have a degree of enmity for the conspiracy theorists because, in my view, they failed.

Despite…

Their YouTube documentaries being viewed billions of times.All the books and white papers they wrote.All the 9/11 truth conferences and activism that happened.All the friendships and Thanksgiving dinners made awkward by that one guy who insisted on talking about 9/11.

…the governments of the world were still able to use 9/11 as a pretext for this decades-long war on terrorism that has burned trillions of dollars and lives and accomplished very little. Without 9/11 and the resulting geopolitical events, Europe would likely not have developed all of its Islamic problems that have resulted in Draconian anti-free-speech hate speech laws being enacted. Through Google, the government can spy on our every word and deed through technology that has seeped into nearly every aspect of our lives.

It was said in the Soviet Union that the only time you could actually freely speak your mind was to your wife, in your bedroom, with the lights out, in bed in low tones under the covers. Well, now that we all use our damn smartphones in bed, you need to worry about the government spying on you even there!

I’ll add that YouTube is RUTHLESS about …

The Epigenetic Vitamin is Tasty!

But that’s not the only thing that makes NMN the best NAD+ source...

I was pleased to receive our package from Youth & Earth promptly (and without any customs fees or paperwork!) NMN was the first supplement my wife and I took. After reading and hearing so many good things about NMN, I was excited to try it. We began by taking just one little scoop once daily. Apparently. the ideal way to take NMN is sublingually, but like Dr. David Sinclair, I just dumped mine in the tasty Bulgarian probiotic yogurt that I enjoy every day.

Got EMFs?

I strongly recommend doing a supplemental cycle of an NAD+ precursor (like NMN) if you, like me, don’t plan on giving up your smartphone to mitigate EMFs. As we learned in the book EMF*D, the non-ionizing radiation from your smartphone and wifi is toxic; it hurts your sleep quality and causes DNA damage. If you live in a city, there’s no way to get away from these EMFs; you can get rid of your wifi router, but will your neighbors? Unless you’re going to go full Into the Wild and flee from society, your biology will have to deal with toxic EMFs, so do a cycle once or twice a year of an NAD+ precursor-like NMN to fuel your PARP system that repairs DNA damage.

Sip NMN cofactors

NMN has two important cofactors: Resveratrol and Pterostilbene. NMN is not cheap stuff, so you would want to take it with these two to maximize the biological bang for your biohacking buck - I created the Epigenetic Awesomeness Protocol for cycling the three. But if you know much about red wine, you’ll know that grape skin is a concentrated natural source of both Resveratrol and Pterostilbene. So, having just completed 3 months of no boozing, NMN gave me a great excuse to have a glass or two of vino daily! Contrary to what the mainstream media told you, red wine is not “healthy,” BUT Youth & Earth also sent me a bottle of tasty mango-flavored Liposomal Glutathione solution, which is renowned as a boozing biohack. The master antioxidant keeps hangovers at bay and does much to repair the damage wrought by the acetaldehyde that alcohol metabolizes into.

If you’re a puritanical biohacker, supplement Resveratrol and/or Pterostilbene alongside NMN, BUT if you’re an ethical hedonist like myself, supplement Glutathione, and tip back a bit of red stuff guilt-free!

NMN fits into the overlapping categories of anti-aging biohack and perhaps Nootropic, but not Smart Drug. It didn’t have any classic energizing Nootropic effects. At a dosage of 250 milligrams daily, the cognition-enhancing effects are very subtle, if noticeable at all.

Having now tried both NMN and NR (Nicotinamide Riboside), NMN is my favorite for the simple reason that it doesn’t taste bad at all (as many powdered supplements do).

Overview of recent NMN science

A few years back, I did a deep-dive meta-analysis article and podcast about NMN; here I’ll summarize the more recent studies and scientific findings. Four clinical trials with NMN have been completed at this point, totaling 191 human participants...

* The virgin trial was completed in 2019 in Japan and gave the epigenetic vitamin to healthy men in dosages ranging from 100 - 500 milligrams and deemed NMN safe.

* A more rigorous randomized, placebo-controlled, double-blind trial with 25prediabetic American women was published in 2021 in the esteemed journal Science. Its abstract concludes: NMN increases muscle insulin sensitivity, insulin signaling, and remodeling in women with prediabetes who are overweight or obese...

* A 2021 Chinese trial evaluated NMN as an athletic performance enhancer, giving it to 48 young and middle-aged recreationally trained runners in 300-, 600-, and 1200-milligram dosages. And it improved aerobic capacity in a dose-dependent manner, so the runner got more power out of the 1200-milligram dose than the 300-milligram dose, as you would expect. With the exception of the single-leg stance test - apparently, 600 milligrams was significantly better than 1200 milligrams if you’re going to stand like this.

* A second clinical trial was done in Japan in 2022, evaluating its effects on Sleep Quality, Fatigue, and Physical Performance in Older Japanese Adults with over 100 human participants. Its abstract concluded: NMN intake in the afternoon effectively improved lower limb function and reduced drowsiness in older adults. These findings suggest the potential of NMN in preventing loss of physical performance and improving fatigue in older adults.

The very most recent peer-reviewed review article published in 2022, a collaboration between Chinese and Kiwi (New Zealand), looked specifically at the Promises and safety concerns of NMN and compares NMN with other NAD precursors, and it comes out looking like the king of the category...

In regard to DNA damage

...nicotinamide supplementation induced DNA damage and oxidative DNA damages in various tissues of the body such as renal and hepatic tissues... NMN has been proven to reduce DNA damage and accumulation of ROS

And insulin sensitivity in comparison with Nicotinamide Riboside

Shi et al. have shown that excessive dose of NR generated white adipose tissue dysfunction and heightened insulin resistance in mice. However, contradictory results have been reported with NMN supplementation as it reduced adiposity and enhanced insulin sensitivity

But

recently, NR has been granted Generally Recognised as Safe (GRAS) status by the US Food and Drug Administration (FDA), which is yet to be achieved for NMN.

And the 2022 review underlines NMN’s safety; up to 1500 milligrams per kilogram (a pretty extreme megadose) a day for 3 months was found to be entirely non-toxic.

Importantly, this NMN is COA-verified as pure and free of toxins or additives by an accredited UK lab, as are all of Youth & Earth’s products.

This proof of purity is what you should demand when supplement shopping, especially when it comes to a product in this price range. Because of their commitment to quality Youth & Earth makes the cut to be included as a recommended Limitless Mindset Secret Society, pick up over £200 worth of their products and you’ll be eligible for a 30-minute biohacking consultation and membership in our elite biohacker community.

Update: I remain a huge fan of Y&E! Check out this recent deep-dive interview about lifehacking longevity with Edward Van Harmelen of Youth and Earth...

For more informative Biohackers reviews breaking down the science you need to know…

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I write this with a sense of accomplishment, having just finished Ben Greenfield’s +1000-page magnum opus, Boundless. I’m something of a superfan of Ben’s - I read and listen to nearly everything he puts out - and I do recommend this book enthusiastically, but I’ll begin my review with some criticisms...

The book begins with a grandstanding introduction to Ben. He lets you know just how AWESOME he is - how amazingly athletic he is, how successful he’s been in business, how happy his family is, etc. Apparently, he finds time to read “a book every day” while maintaining the physique of a Greek god, being a CEO, and a devoted family man. The implication is “do what I’ve done, and you’ll be like me,” which is not totally misleading: the more you invest in your health, the better your life will get. Biohacking really does broaden your horizons; it’s the most surefire way to wield true free will, rise above mundanity, plot your own course, and take your destiny into your own hands.

But I read the introduction, not thinking Ben was wildly exaggerating, but that he has won the genetic lottery in a major way and then stacked on a bunch of hacks, resulting in his awesome life.If you’re red-pilled on genetics, you know that religion encourages evolutionary fitness; in general, more religious people are more evolutionarily fit. You would expect a tall, good-looking, fervently religious guy descended from American pioneer stock, like Ben, to have a good life because of the special evolutionary pressures put on his ancestors. People often compliment me on my intelligence and intellect, and that’s NOT something I take full credit for; my grandfather was one of the top NASA engineers responsible for getting men to the moon and back. I too have been gifted some by the genetic lottery - which I think Ben should have given some more credit to.

I have to deduct a star for the relentless pitching throughout the book, a criticism that many other reviewers make. Obviously, biohackers need to spend some money on products and supplements to optimize health, but product and brand recommendations are made so frequently that it’s clear that Ben Greenfield & Co did a lot of sponsorship sales pre-publication. There are a couple of issues with this other than the obvious one - a book should NOT be an advertising platform (especially a $55 one!)

* The book will not age well because health companies and brands go out of business, rebrand, discontinue products, and sometimes even sell out to multinational chemical corporations. Napoleon Hill’s iconic Think and Grow Rich would not be such a timeless book if it were urging readers to mail-order Cocaine Tooth Drops from the Sears Roebuck catalog!

* Some of the products are only available to the American market, and (NEWSFLASH) not everyone lives in America.

* It makes it seem like biohacking and healthy living are only for rich people who can afford to spend hundreds of dollars a month on supplements and thousands on fancy biohacking devices and tech. If you’re a biohacker ballin’ on a budget, check out my deep-dive podcast, 33 IMPACTFUL free (or cheap) biohacks & lifehacks.

But I won’t be as harsh as some of the book’s reviewers on this point because the book contains just as many free or cheap things that people can do to optimize their health. Each chapter has an exhaustive recommended resources page on the book’s website, and THAT is the place for affiliate and sponsor recommendations, not in the pages of a pricier book (even the Kindle ebook is $30) that is going to sit on people’s bookshelves for decades!

With those two criticisms out of the way, Boundless belongs on your bookshelf.

I’ve read a few podcasters’ books where basically what they did was copy and paste transcripts of interviews - they book-ified their podcasts - and it just doesn’t translate great; if I wanted interviews, I’d just go listen to the interviews. Stop doing this, podcasters! Thankfully, Ben didn’t do that with Boundless - it’s a real book that follows the compelling format that educational and edifying nonfiction should: Story, Theory, Data, and Pragmatic Takeaway.

How I hack my forgetting of book knowledge

If you’re going to spend hours and hours of your precious time reading nonfiction books for edification, you’re kind of wasting your time if you eventually forget 90% of what you read. The way I hack this is by highlighting passages and facts that I want to commit to memory and then, after finishing the book, adding those with hints to the SuperMemo app. Then it takes me just 15-30 minutes of memory practice a week to stay savvy with hundreds of pieces of semantic memory that I’ve picked up from books (even books I read years and years ago).

To take this to the next level, combine it with mnemonics practice. Using my own creativity and phonetic number pegging, I committed to memory a factoid from every chapter of Boundless. Read some books on Mnemonics because even average memories are remarkably powerful when used properly...

Nootropics vs Smart Drugs

There is a difference...

If a drug is strongly felt on a consistent basis whenever you use it and it makes you high, wired, or sedated, it is acting more like a smart drug or performance enhancer and is likely not a natural nootropic. Nootropics are sustainable for long-term use, while smart drugs are not. (p.127)

Many people use the terms nootropic and smart drug as if they mean the same thing, but they’re actually very distinct. All nootropics are technically smart drugs, but the opposite is not necessarily true. A smart drug is any substance that enhances memory, mood, concentration, or another aspect of cognitive function. Nootropics target the same functions, but by definition they must also be neuroprotective and nontoxic, and they are usually derived from natural, nonsynthetic sources. (p.146)

So Modafinil would be a quintessential example of a non-Nootropic smart drug.

I recorded this podcast/vlog on Zamner Joice and Brain Flow from Nootopia.

Weight training and minimum effective dose of exercise

Quite simply, strength training is one of the most effective anti-aging tools in the aspirational immortals’ toolbox - lift heavy stuff, and you’ll live longer.

A 2007 study demonstrated that six months of progressive resistance training, otherwise known as “lifting heavy stuff,” made the gene expression of aging mitochondria appear to be significantly younger. (p. 318)

The researchers reported: “Healthy older adults show a gene expression profile in skeletal muscle consistent with mitochondrial dysfunction and associated processes such as cell death, as compared with young individuals. Moreover, following a period of resistance exercise training in older adults, we found that age-associated transcriptome expression changes were reversed, implying a restoration of a youthful expression profile.” Yes, you read that right: when it comes to mitochondria, strength training reversed nearly forty years of aging! But exercise doesn’t only affect mitochondria. It also promotes the growth of fat-burning fast-twitch muscle fibers and even protects DNA from the wear and tear of aging by acting on telomeres, the end caps of DNA molecules. (p. 319)

If you want the minimum effective dose of strength training that will help you find the sweet spot between longevity and muscle, you can get away with as few as two strength workouts per week—one with slow, controlled heavy lifting and one with high-intensity bodyweight movements. (p. 328)

Blood Flow Restriction Bands (which you can get for under $50) are a real time-saving shortcut for fitness and strengt…

Another Nootropic peptide that empowers the mind, although it’s better for treating brain disorders than it is for healthy people to use as a smart drug.

15 results and just a single 2012 clinical trial can be found on PubMed; interestingly, they treated 150 Russian truck drivers with neurotic disorders (I can just imagine how grueling a job being a trucker in Russia must be!) with peptides. To quote the study:

The best effect was obtained in case of combined application of several cytogens (pinealon and vezugen), which were optimally selected regarding the effect of each adverse occupational factor on a target organ or system. The employed parameters of psychoemotional state were rather informative for assessing the peptidergic properties of cytogens in occupational medicine and geriatrics.

So taking Pinealon may be great for those with jobs that really take a mental toll. It’s also used to treat...

* Poor memory

* Attention deficit disorder

* Brain injury and stroke

* Alzheimer’s

* Parkinson’s

* Atherosclerosis and multiple sclerosis

Along with curing neuralgia, neuritis, and encephalopathy.

Anecdotally, it’s described as a quintessential Nootropic. A user on Reddit praised it:

...I took Pinealon for 30 days and anecdotally I noticed improved mood, sleep, and concentration without becoming mentally fatigued. In a way it reminded me of Semax, and I will definitely be trying it again via the nasal ROA in another month or two. So far I’ve been very impressed with every Russian nootropic I have tried.

A Longecity.com user reports:

Pinealon is a good example, it just gives you that extra level of clarity and speed of thought, and memory, which makes your day more productive and thus, ultimately, more satisfying.

The precocious biohacker Lostfalco found it euphoric:

I wasn’t expecting to ‘feel’ anything from them at all, but Pinealon, especially, made me feel fantastic. My gf had to tell me to stop talking about how amazing it was...but I didn’t.

Biohacker Review

I took PINEALON for about a month, two capsules a day in the morning. It has a very subtle effect as a cognitive enhancer; I noticed myself being just a little quicker in my problem-solving and deduction. I had hoped that it might have a cumulative effect on improving my memory and recall, but I did not, as far as I can tell. I’ve tried a number of “memory-enhancing” Nootropics, and the only one that seems to actually have this effect is Piracetam. PINEALON is worth the attention of those who want to arrest and treat cognitive decline, but I don’t regard it as a performance-enhancing smart drug for biohackers.

About smart peptides

Bioregulatory Peptides are a novel class of medicine that hack our biology on the genetic level.I say novel because they are a relatively recent development and have thus far not been largely acknowledged and studied by the Western medical establishment. For those looking for healing solutions outside the mainstream offerings of the pharmaceutical-industrial complex, these peptides are worth learning about.

from Perplexed by Peptides?

About PINEALON® for the brain, 60 caps/pack

PINEALON® is a natural bioregulator containing active peptide complex. It is developed to recover the brain and to treat poor memory, attention difficulties, brain injury, stroke, high stress, chronic fatigue, depression, insomnia, irritability, Alzheimer’s, Parkinson’s diseases, multiple sclerosis, as well as to maintain the functional status of the brain in elderly patients. Pinealon contains amino acids that integrate into the DNA structure of the brain, thus reducing their peptide deficiency and restoring protein synthesis inside their cells.

USES

Treat Atherosclerosis, Multiple Sclerosis.Eradicate Alzheimer’s and Parkinson’s Diseases.Cure Neuralgia and Neuritis, Encephalopathy.Preoperative and Postoperative Periods.Reduce the Consequences from Neuro-Infections, Traumatic Brain Injury.

From RUPharma.com

For more reviews and overviews of peerless peptides…

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