Peter Hayward talks to Dr Bridget Mugisa (WHO, Eastern Mediterranean Office, Egypt) about a study summarising the epidemiology of HIV in the Middle East and north Africa.

Dr Amy Justice (Yale University, USA) talks to Philippa Harris about the joint The Lancet HIV and The Lancet Healthy Longevity Series Ageing with HIV.

Adrian Gonzalez is joined by Jose M. Zuniga (IAPAC, Fast-Track Cities Institute and UNAIDS Task Force on Urban Health) to talk about the IAPAC – Lancet HIV Commission on the future of urban HIV responses.

Florence Riako Anam (Global Network of People Living with HIV, Kisumu, Kenya) and Bruce Richman (Prevention Access Campaign in New York, USA) join Adrian Gonzalez to discuss the importance of a clear message on U=U to end AIDS as a public health threat.

Adrian Gonzalez entrevista a Claudia Cortes (Universidad de Chile, Santiago de Chile) y Giovanni Ravasi (Equipo de América Latina y Caribe del Fondo Mundial, Ginebra, Suiza) sobre los desafios a los que se enfrentan las poblaciones migrantes en el marco de la prevención y el tratamiento del VIH.

Sharon Lewin (Peter Doherty Institute for Infection and Immunity, Melbourne, Australia) joins Deputy Editor, Adrian Gonzalez to talk about the requirements and challenges to develop a product for HIV cure based on cell and gene therapies.

Peter Hayward is joined by Debra ten Brink and Rowan Martin-Hughes of the Burnet Institute (Melbourne, Australia) as they discuss their modelling study forecasting the effects of funding cuts on HIV acquisitions and mortality.

Sari Reisner (University of Michigan School of Public Health, Boston, USA) on gender-affirming hormone therapy for transgender, non-binary, and gender-diverse people in the US and its effects on HIV acquisition risk and viral suppression.

Lisa Noghuchi of Jhpeigo (Johns Hopkins University) and Nyaradzo Mgodi (University of Zimbabwe) join Peter Hayward to discuss the MTN-043 study assessing safety and drug exposure of the dapivirine ring in breastfeeding women.

Editor-in-Chief Peter Hayward is joined by Adrian Gonzalez (Deputy Editor) and Richard Henderson (Senior Editor) to reflect on 10 years since the launch of The Lancet HIV.