Editor-in-Chief, Peter Hayward, talks to researchers from London School of Hygiene and Tropical Medicine and Melanie Alufandika-Moyo Malawi-Liverpool Wellcome Trust about their research on virological failure and HIV drug resistance in patients with HIV in hospital in Malawi.

Researchers from the Medical Research Council Clinical Trials Unit at University College London join Editor-in-Chief Peter Hayward to discuss paediatric HIV treatment and the pharmacokinetic substudy of the ODYSSEY trial of dolutegravir for children with HIV.

Deputy Editor Philippa Harris talks to Chi-Chi Udeagu (New York City Department of Health and Mental Hygiene, USA) about HIV partner services in New York City and the impact of COVID-19.

Kelly Dooley (Johns Hopkins University, USA) and Gavin Churchyard (Aurum Institute, South Africa) discuss their trial on tuberculosis prevention in people with HIV taking dolutegravir-based antiretroviral therapy with Deputy Editor Philippa Harris.

Adam Castillejo joins The Lancet HIV’s Editor, Peter Hayward, to talk about his experience of HIV, cancer, and becoming the second person to be cured of HIV.

Deputy Editor Philippa Harris discusses viral load testing with Paul Drain (University of Washington, USA) and a trial of point-of-care testing with task shifting to improve treatment outcomes.

Joseph Kagaayi (Rakai Health Sciences Program, Uganda) and Oliver Ratman (Imperial College London, UK) talk to Editor-in-Chief Peter Hayward about the world famous research site and the insights that deep sequencing has provided into the flow of HIV in their latest research.

Marta Nunes (University of the Witwatersrand, Johannesburg, South Africa) talks to Philippa Harris about vaccination response in people living with HIV and a trial of influenza vaccine dosing in pregnant women with HIV in South Africa.

For World AIDS day, The Lancet HIV Deputy Editor Philippa Harris talks to Jeff Lazarus and Nikos Dedes about the importance of good health-related quality of life and the barriers people living with HIV face in achieving this.

Giuseppe Pantaleo (Service of Immunology and Allergy, Department of Medicine, Lausanne University Hospital, Switzerland) tells Peter Hayward about a phase 1 vaccine study published in the November issue of The Lancet HIV, and gives an overview of the HIV vaccine field.