On this all-new E! News, music's biggest stars including Beyonce, Cher and Taylor Swift all showed up for the iHeartRadio Music Awards and we have all the sizzling highlights! '90210' star Shannen Doherty shares a heartbreaking update on her cancer journey, and Lizzo speaks out after revealing to her followers that she "quit" last week! Next, Vanna White and Jared Leto play the ultimate April Fools' Day joke on 'Wheel of Fortune' and Rebel Wilson gets candid about losing her virginity at 35 years old. Plus, Colin Farrell shares details on his upcoming movie with Margot Robbie and 'Vanderpump Rules' star Lala Kent joins us live in studio!

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