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The prospect of long-term solitary confinement, being housed alone in custody for months and sometimes even years, is daunting for criminal defendants and their counsel. In May 2023, two public interest organizations, The Italian Association Antigone and the Israeli organization, Physicians for Human Rights Israel, proposed the International Guiding Statement on Alternatives to Solitary Confinement. We are pleased to have with us two guests: Professor Keramet Reiter & Oneg Ben Dror. Professor Reiter is a member of the Department of Criminology, Law and Society at the University of California Irvine Law School. Professor Reiter is the author of 23/7: Pelican Bay Prison and the Rise of Long-Term Solitary Confinement, published by Yale University Press. Ms. Ben Dror is a project coordinator for the Physicians for Human Rights Israel, and was involved in the drafting of the International Guiding Statement on Alternatives to Solitary Confinement. Our guests are the co-authors, along with Dana Moss, of a recent article: Overview of the International Guiding Statement on Alternatives to Solitary Confinement in the Criminal Justice Magazine.