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Delving into the dark depths of science this week is Ron Douglas who describes the fascinating world of deep sea fish, bioluminescence and the sights from a deep sea sub, Jason Hall-Spencer talks about cold water corals and the threats posed by fishermen, and in slightly warmer waters David Kline reveals how Caribbean corals are suffering due to sugar pollution. Also in the show, Fran Beckerleg interviews John Ablett about a giant squid called Archie, and getting the low down on the high seas Derek finds out how a submarine works in Kitchen Science.

Bringing a ray of sunshine to the studio this week is Alex Hill from the London Met Office, who will be describing how meteorologists predict the weather on a daily basis, Tim Palmer reveals how understanding seasonal weather patterns can help scientists to predict outbreaks of malaria, Emily Shuckburgh discusses how faraway oceans can affect our local weather, Fran Beckerleg braves the roof of the London Weather Centre, and Sheena Elliott joins Derek Thorne in Kitchen Science to shed light on why the sky is blue.

Picking apart the inner workings of our brains this week are Irene Tracey, who discusses the neurological origin of pain and how we can reduce pain, Philip Shaw reveals why having a bigger brain does not make you more intelligent, Kathleen Taylor talks about her new book on brainwashing, including whether brainwashing is a real phenomenon and how we can avoid it, and from brainwashing to the bathtub, Derek Thorne scrubs up on density in Kitchen Science.

Answering all your burning science, technology and medicine questions this week are Drs Chris, Dave and Phil, who will be looking at why purifying seawater is not the answer to water shortages, how 3D glasses work and whether a man on a meteor would have to hold on tight or just soak up the stellar scenery. Also on the show, Daniel Scuka at the European Space Agency provides a Venus Express update, Diana Liverman talks about how to turn down the heat on climate change, and in Kitchen Science Anna Lacey finds out why we hear strange voices when we play old records backwards.

Conservation and saving species go under the spotlight this week as Henry Nicholls draws attention ot the plight of Lonesome George, the last giant tortoise of his kind, David Aldridge discusses the problem of invasive species and how he is purging freshwater ecosystems of zebra mussels with a poison pill, Chris interviews Rick Shine about the wave of invasive cane toads legging it across Australia, from waves to the ocean, Helen Scales discusses the issues behind marine conservation, and sticking with the watery theme, Derek Thorne whips up a storm in Kitchen Science.

Time is very much the essence of this weeks show, as Russell Foster discusses the human body clock, where the body clock is and how it gives our bodies a daily rhythm, Karl-Arne Stokkan describes how reindeer body clocks adapt to twenty four hours of sunlight, Alex Webb talks about plant circadian rhythms and how they differ from animals, and Anna Lacey interviews Cynthia Kenyon about how to survive longer and cheat time.

The recycling revolution and the whereabouts of our waste are hot topics this week as David Butler describes a new technique for recycling water, Rebecca Weymouth lifts the lid on what happens to our domestic waste, Peter Barham reveals why plastic is so difficult to recycle, and Richard Thompson discusses how waste plastic threatens the environment. In Kitchen Science Derek turns old chip oil into biodiesel, and from making fuel to running on empty, Anna Lacey asks Andrew Prentice how humans cope with famine.

Picking apart some miniature morsels of science this week are David Carey, who provides the big picture on the world of nanotechnology, Donald Fitzmaurice describes how DNA may be used as scaffolding for the next generation of computer chips, we breach the boundaries between physics and biology as Stephen Webb discusses how new microscopes can see developing cancers at the nano-scale, and Neal Morgan explains how nanoparticles are stamping out stinky socks. Also on the show, Jim Clark digs up the ancestors of T. rex, and in Kitchen Science Derek and Dave dish the dirt on how gravy thickens.

Unlocking Natures medicine chest are doctors orders this week as Monique Simmonds reveals the research behind old herbal remedies, Tai-Ping Fan describes how Chinese medicine is being used for illnesses from gout to endometriosis, Jack Cuzick talks about clinical trials for a new drug for breast cancer, and Dr Chris is in St. Louis with details on a potato that fights back... In Kitchen Science, Derek unleashes the explosive power of flour, and Anna Lacey asks Peter Austin why thousands of languages are threatened with extinction.

Love, seduction and sexual attraction are in the air this week as Peter Brennan woos Chris and Kat with a discussion of pheromones and the science of smell, Charles Wysocki suggests how farmers can love thy neighbour by masking the stench of manure, we hit the dancefloor with William Brown who reveals the recipe for success at the Saturday night disco, and Peter Barham talks about the science of taste, food and the ingredients for a perfect Valentine meal!