LONGEVITY with Nathalie Niddam

If you’ve been wondering what exactly bioregulators are and what differentiates them from the peptides you’re already familiar with, then this episode is for you. 

Today we’re diving into the world of bioregulator peptides, and covering everything from how they work to where they come from. We’ll also discuss why there has been an increasing number of physicians that are starting to implement bioregulator peptides into their protocol, and how bioregulators are often used in conjunction with conventional therapy. We’ll also talk a bit about the history behind bioregulators, and the connection between bioregulator peptides and the 12 hallmarks of aging.

Thank you to our sponsors for making this episode possible:

Sensate: Use promo code NAT at getsensate.com to save 10% on your order.

Find more from Nathalie:

Find More From Nathalie
YouTube: https://www.youtube.com/channel/UCmholC48MqRC50UffIZOMOQ
Facebook Group: https://www.facebook.com/groups/biohackingsuperhumanperformance
Instagram: https://www.instagram.com/nathalieniddam/
Website: NatNiddam.com
Join Nat’s Membership Community: https://www.natniddam.com/bsp-community
Work with Nat: Book Your 20 MInute Optimization Consult: https://calendly.com/nniddam/intro-call?month=2021-08

What we discuss:

[00:07:08] A bioregulator peptide is an epigenetic switch

[00:09:03] Who discovered bioregulators? 

[00:11:55] Other than our own bodies, where else can we get bioregulators from? 

[00:13:31] Taking extracts from tissues, glands, and organs to isolate bioregulator peptides 

[00:17:31] The three different forms of bioregulator peptides

[00:21:54] How safe are bioregulator peptides?

[00:22:45] What are some of the organ systems that bioregulators address? 

[00:25:34] Why bioregulators are often used in conjunction with conventional therapy

[00:26:35] Why bioregulators don't need to be used indefinitely 

Key Takeaways:

• Bioregulator peptides are molecules that can act as epigenetic switches, meaning they can modify gene expression without altering the genetic code itself. By selectively

You may have already heard how important organ meats are when it comes to health optimization, but many people still shy away from the idea of consuming these organ meats in place of a steak.

But the truth is that the nutrients found in organ meats play a crucial role in supporting immune function, brain health, and energy metabolism, and my guest today is here to share why we should all be incorporating these nutrient-rich organs into our diet.

I’m joined by James Barry, the founder of Pluck seasonings, to discuss the many benefits of eating organ meats. We discuss why as a society we have moved away from eating organ meats, and the perception that certain foods are healthier than others. James also explains why he decided to start making Pluck seasonings, and how these organ meat seasonings compare to eating the real thing.

James Barry’s 17 + years in the culinary field started as a private chef cooking for celebrities such as Tom Cruise, Mariska Hargitay, George Clooney, Gerard Butler, Sean “Puffy” Combs, Barbra Streisand, and John Cusack. Most recently, James launched his first functional food product, Pluck, an organ-based seasoning. It's the first of its kind and an amazingly easy and delicious way for people to get organ meats into their diet.

James is also a published cookbook author having co-authored the recipes in Margaret Floyd’s book Eat Naked and co-authored the follow-up cookbook The Naked Foods Cookbook. He most recently co- authored the recipes in Dr. Alejandro Junger’s book, Clean 7. 

Thank you to our sponsors for making this episode possible:

Eat Pluck: Use code BSP10 to save 10% on your order at eatpluck.com

Profound Health: Go to Profound-health.com and use promo code Longevity15 to save 15% on your first order. 

Find More From Nathalie:
YouTube: https://www.youtube.com/channel/UCmholC48MqRC50UffIZOMOQ
Facebook Group: https://www.facebook.com/groups/biohackingsuperhumanperformance
Instagram: https://www.instagram.com/nathalieniddam/
Website: NatNiddam.com
Join Nat’s Membership Community: https://www.natniddam.com/bsp-community
Work with Nat: Book Your 20 MInute Optimization Consult: https://calendly.com/nniddam/intro-call?month=2021-08

Did you know there is a connection between spirituality, a balanced nervous system and longevity? When it comes to biohacking, we focus primarily on the supplements we can take, the peptides we can use, and the different  technology we can implement into our daily life. But, what many of us forget, is that our mental wellbeing plays a huge role in our health. We can do all the biohacks we want, but if our mental health is not balanced, we’ll struggle to optimize our health and longevity…plus, the brain-gut connection is a real thing! 

My guest today is here to discuss why there’s more to the pursuit of longevity than just biohacks and supplements.

I’m joined by Danielle LaPorte, and we’re diving into the spiritual side of longevity and covering the corollary between the spiritual striving and the physical striving. We also discuss why a person's health history can be the key to healing, things you can do to eliminate any obstacles within your body, and how to balance your sympathetic nervous system with your parasympathetic nervous system. 

Danielle LaPorte is a member of Oprah’s SuperSoul 100 a group who, in Oprah Winfrey’s words, “is uniquely connecting the world together with a spiritual energy that matters.” Danielle is the creator of the Heart Centered Membership and the Heart Centered Leadership Program with 400+ leaders in 30 countries hosting conversation circles, retreats, and workshops in all kinds of communities and businesses.

What we discuss:

00:03:18: The light side and the shadow side of our obsession and pursuit of longevity 

00:09:43: The corollary between the spiritual striving and the physical striving

00:14:36: The metaphors of the body

00:19:24: The correlation between pain and fear 

00:26:01: The misperception that spiritual people are healthy all the time 

00:35:16: Why going through a person's health history can be the key to healing

00:41:19: Why your entire life needs to revolve around regulating your nervous system 

00:49:35: When we start to think differently, we will attract the right kind of healthcare providers 

00:55:22: By accessing the energetic force within yourself, you can eliminate any obstacles within your body

Thank you to our sponsors for making this episode possible:

Primeadine: Use promo code BIONAT15 to save 15% on your first order at https://oxfordhealthspan.com/products/best-spermidine-supplement 

Sensate: Use code NAT to get 10% off at https://bit.ly/NatNiddam

LVLUP: Use code NAT10 to save 10% off at https://lvluphealth.com/

Find more from Nathalie:

YouTube: https://www.youtube.com/channel/UCmholC48MqRC50UffIZOMOQ
Facebook Group: https://www.facebook.com/groups/b

While you may be familiar with the nine hallmarks of aging, over the past several years there have been an additional five added to that list. It might seem overwhelming to have 14 aging processes to keep up with, but it's important to understand that many of them, if not all of them, are essentially interrelated. 

One thing we’ve learned about these processes that drive aging are that they are done at a cellular and systemic level. This gives us the opportunity to try and intercept and correct them so that we can live longer, healthier lives.

I’m joined by Leslie Kenny, Founder of Oxford Healthspan and Co-Founder of the Oxford Longevity Project. We’re talking all about the hallmarks of aging, including how the processes are interconnected, and what we can do to slow these processes down. We also dive into polyamines, specifically spermidine, and how it can boost autophagy.

Leslie Kenny is an autoimmune survivor/thriver, certified health coach and Founder and CEO of Oxford Healthspan, bringing to consumers the latest scientifically based molecules proven to slow aging.

She is also the Co-Founder of the non-profit Oxford Longevity Project which aims to bring the latest scientific breakthroughs on healthy aging to the general public. Leslie holds degrees from Berkeley and Harvard.

What we discuss:

00:01:38 - The symposiums and organizations Leslie is connected to 

00:11:21 - The first nine hallmarks of aging

00:15:25 - Inflammation, gut dysbiosis, and autophagy 

00:22:22 - The effects of fasting on the body

00:30:09 - The dysregulated RNA process

00:36:03 - What are polyamines?

00:44:42 - How do people get polyamines into their diet? 

00:51:40 - Synthetics vs. food derived 

00:57:17 - The benefits of spermidine supplements 

Key Takeaways:

• Polyamines are derived from amino acids, and they play a role in slowing down the process of aging. The most well known polyamine is spermidine, and it helps to boost autophagy.

• There are many other molecules in foods and whole food sources, so it is important to consume nutrients through eating whole foods.

• The body is able to regenerate and self renew itself if we're able to remove the obstacles and facilitate those processes.

• Leslie’s top suggestions for longevity include eating intentionally, joyful movement, sleep, and early morning sunlight.

Find more from Nathalie:

YouTube: https://www.youtube.com/channel/UCmholC48MqRC50UffIZOMOQ

Facebook Group: https://www.facebook.com/groups/biohackingsuperhumanperformance

Instagram: https://www.instagram.com/nathalieniddam/

Website: NatNiddam.com

Join Nat’s Membership Community: https://www.natniddam.com/bsp-community

Work with Nat: Book Your 20 MInute Optimization Consult:

What if there was a way to help detox your body, boost your mood, burn calories, and get glowing skin in just under 45 minutes a day? The good news is that there is, and my guest today is sharing the secret to elevating your at-home wellness routine.

Today we’re diving into the world of infrared, PEMF, and red light and discussing the many benefits of infrared saunas. 

I’m joined by Lauren Berlingeri, one of the founders of HigherDOSE. Lauren is discussing her background and what inspired her to start HigherDOSE, and explaining some of the differences between infrared saunas and traditional heat saunas. She shares everything you need to know about when and how to use an infrared sauna, plus some of the benefits of detoxing daily.

As a female biohacker, Lauren is passionate about inviting more people into the biohacking world and reimagining these tools for all bodies — so you can reconnect with your intuition and elevate to your highest state. She is making it sexy to sweat it out and even hotter to know the science behind what’s happening. She is harnessing the healing power of nature and fitting it into busy, overstressed schedules. And, she is changing the way you think about beauty and wellness by building tools that ignite vitality from the inside out.

What we discuss:

00:00:50 - What inspired Lauren to start Higher Dose

00:06:53 - Infrared vs. regular heat

00:13:09 - How to prepare your body before going into an infrared sauna

00:20:46 - Why you should detox daily

00:25:04 - Lauren’s favorite three biohacks

00:33:00 - The best time to use an infrared sauna

00:38:14 - Research around menopausal women and red light

00:44:10 - Pros and cons of the sauna blanket 

00:53:47 - How long should you use the sauna blanket? 

01:00:30 - Other HigherDOSE products

Key Takeaways:

• Infrared saunas heat the body at a much lower temperature, so it's much more gentle on the body.  

• The four main happy chemicals are dopamine, oxytocin, serotonin, and endorphins, and they are released with the use of infrared saunas.

• Before using an infrared sauna, it’s important to prepare your body by opening up your detox pathways. 

Find more from Nathalie:

YouTube: https://www.youtube.com/channel/UCmholC48MqRC50UffIZOMOQ
Facebook Group: https://www.facebook.com/groups/biohackingsuperhumanperformance
Instagram: https://www.instagram.com/nathalieniddam/
Website: 

I’m joined by Dr. Bill Harris, PhD, FASN, President of the Fatty Acid Research Institute and Founder of OmegaQuant Analytics. We’re diving into omega-6s and omega-3s and discussing the benefits of these fatty acids and where they come from. We also cover the importance of maintaining a ratio of omega-6 and omega-3, and whether or not omega-3s have an effect on blood clotting and blood circulation.

Dr. Harris has been a leading researcher in the omega-3 fatty acid field for over 40 years. He has more than 300 scientific papers on fatty acids and health, the vast majority on omega-3. He has been on the faculty of three medical schools (Universities of Kansas, Missouri (at Kansas City), and South Dakota), and has received 5 NIH grants to study omega-3. He was the co-author on three AHA statements on fatty acids and heart health. As the co-inventor of the Omega-3 Index (and other omega-3 blood tests) and founder of OmegaQuant Analytics, Dr. Harris has been ranked among the top 2% of scientists worldwide based on the impact of his research. 

What we discuss:

00:02:38 - Omega-3s and their effects on blood clotting and blood circulation 

00:07:23 - The value of omega-6

00:11:54 - The ratio of omega-6 and omega-3

00:18:03 - Where do arachidonic acid and linoleic acid come from, and what do they do?

00:25:22 - The components of omega-3s

00:31:04 - EPA and DHA  

00:41:35 - Is there a relationship between omega-6 and omega-3 levels and longevity?

00:46:31 - Fish as a source of omega-3 

00:57:21 - Mammalian sourced omega-3s

01:06:35 - 3 things to keep in mind about omega-3s and omega-6s 

Key Takeaways:

• Looking at levels of omega-6 fatty acids in the blood can predict future diseases like heart disease and diabetes. 

• Increasing your levels of omega-3 is more important than worrying about getting your omega-6 levels down in order to have a good ratio between the two. 

• It’s important to measure your omega-3 levels. These levels are predictive of good health outcomes and even cholesterol levels. 

Find more about Nathalie:

YouTube: https://www.youtube.com/channel/UCmholC48MqRC50UffIZOMOQ

Facebook Group: https://www.facebook.com/groups/biohackingsuperhumanperformance

Instagram: https://www.instagram.com/nathalieniddam/

Website: NatNiddam.com

Join Nat’s Membership Community: https://www.natniddam.com/bsp-community

Work with Nat: Book Your 20 MInute Optimization Consult: https://calendly.com/nniddam/intro-call?month=2021-08

Find more about Dr. Bill Harris:

Website: www.omegaquant.com, www.fareinst.com 

Facebook: https://www.facebook.com/Omega3Index

Instagram: https://www.instagram.com/omega3index/?hl=en

LinkedIn:

You've probably heard about peptides, and you may be wondering, “What are peptides? Why do I need to know about them?” At the end of this episode, you’ll have the answers to these questions, plus so much more.

We’re diving into the basics of peptides, and I'm going to answer some very commonly asked questions about both peptides and bioregulators. We’re covering everything from the most important things to remember about peptides, to the different ways peptides can be administered. If you want to learn how peptides work, the benefits of BPC-157, and why most peptides are not FDA approved, you’ll want to tune into this episode.

What we discuss:

00:03:34: What are peptides?

00:04:26 Insulin is a very well known peptide

00:05:33: Why most peptides are not FDA approved

00:07:49: Why there’s not a lot of information about peptides in healthcare

00:09:35: How do peptides work? 

00:11:20: The benefits of BPC-157

00:14:14: Using peptides topically

00:17:49: Important things to remember about peptides 

00:20:07: The importance of getting peptides from a trusted supplier

00:21:27: Bioregulator peptides

00:23:59: Why bioregulators are highly bio-available orally 

00:29:51: Where to find bioregulator peptide supplements 

Key Takeaways:

• Bioregulator peptides have been shown to help to extend human life, to reverse biological age and to restore function.

• When you have a string of amino acids that's either 50 amino acids or less, that is automatically called a peptide.

• The most common way that peptides are introduced into the body is by subcutaneous injection.

• Copper peptides are very powerful when used topically, which is why a lot of beauty products incorporate copper peptides.

Find more from Nathalie:

YouTube: https://www.youtube.com/channel/UCmholC48MqRC50UffIZOMOQ

Facebook Group: https://www.facebook.com/groups/biohackingsuperhumanperformance

Instagram: https://www.instagram.com/nathalieniddam/

Website: NatNiddam.com

Join Nat’s Membership Community: https://www.natniddam.com/bsp-community

Work with Nat: Book Your 20 MInute Optimization Consult: https://calendly.com/nniddam/intro-call?month=2021-08

Thank you to our sponsors for making this episode possible:

LVLUP: Use code NAT10 for 10% off your order at https://lvluphealth.com

Have you ever struggled with weight loss and thought to yourself, “I’m doing everything right…I have a healthy diet, I’m exercising, but the weight just won’t come off”? You’re not alone, and today we’re discussing how your hormones could be impacting not only your weight loss, but many other aspects of your life.

I’m joined by Karen Martel, a Certified Hormone Specialist & Transformational Nutrition Coach and women’s weight loss expert. We’re diving into the world of hormones, specifically how hormone imbalances can play a major role in weight loss, insomnia, depression, and some diseases. Karen also shares how she is an advocate for women taking charge of their hormones as they move through different stages of life.

 Karen is the host of the top 100 rated women’s health podcast The Other Side of Weight Loss where she helps women to unlock the mysteries of female fat loss and hormone imbalance.

After struggling with her own health issues, Karen was determined to bring her knowledge to others with a bold new approach to women’s hormone health and weight management. Karen’s passion lies in helping women balance and optimize their hormones in peri and post menopause and breakthrough weight loss resistance.

What we discuss:

00:01:55 - How Karen got into the hormone space 

00:10:54 - Why perimenopause is happening earlier

00:15:48 - How toxins are affecting hormones 

00:19:15 - Birth control and the studies on progestin

00:25:50 - How the loss of hormones drives breast cancer 

00:29:10 - Estrogen in the brain

00:37:20 - How estrogen is partly responsible for the production of serotonin and dopamine 

00:45:45 - Ways to help treat severe PMS

00:53:01 - Why estradiol is so important

00:59:47 - How hormones and peptides go hand in hand for anti-aging

Key Takeaways:

• There are a lot of chemicals in our environment that mimic hormones, and they are a lot stronger than your own actual hormones. It is important to try and clean up your immediate environment from all the toxic chemicals to prevent your body from running on these fake chemical hormones. 

• The loss of hormones drives almost every disease that is dangerous to women, especially breast cancer. 

• In the second half of your cycle when you start to produce progesterone, some women get severe PMS, which is also known as Premenstrual Dysphoric disorder (PMDD). The symptoms can include increased anxiety and severe depression.

Find more from Nathalie:

YouTube: https://www.youtube.com/channel/UCmholC48MqRC50UffIZOMOQ

Facebook Group: https://www.facebook.com/groups/biohackingsuperhumanperformance

Instagram: https://www.instagram.com/nathalieniddam/

Website: NatNiddam.com

Join Nat’s Membership Community: https://www.natniddam.com/bsp-community

Work with Nat: Book Your 20 MInute Optimization Consult: https://calendly.com/nniddam/intro-call?month=2021-08

Find mo

If we look back at the last 200 years, we can see that human evolution was not designed to deal with the drugs, chemicals, and pollutants that are part of the modern day world. This is why it is so important to support liver health for our overall well-being.

The liver is basically our processing plant for toxins. And it all comes back to gut health - when we have negative bacteria in our gut, that directly affects our liver detoxification pathways.

I’m joined by Kyal Van Der Leest, founder of LVLUP Health. We’re discussing everything you need to know about how to optimize your liver health, and how it connects to the health of your gut. We also dive into the skin issues that can arise from the body releasing toxins, and how if your detox pathways aren't optimized, your skin is ultimately not going to look as good as it could.

Kyal Van Der Leest is a nutritionist, naturopath, and functional health coach turned formulator who now runs LVLUP Health. He founded LVLUP Health to create powerful cutting edge supplement tools that people could use to improve their health using the unique formulations that combine orally bioavailable peptides with naturopathic botanicals and nutritional supplement ingredients. 

What we discuss:

00:02:29 - Why all health begins in the gut 

00:04:35 - The different phases of detoxification 

00:11:25 - Are detox products beneficial? 

00:19:58 - The Complete Liver Complex

00:26:24 - How TUDCA works

00:33:29 - How releasing toxins can result in skin issues 

00:40:44 - How AHK supports the culture networks of the skin

00:44:00 - Botox-like peptides 

00:50:21 - How Botox can have an effect on your liver 

01:02:28 - How the peptide Svetinorm is beneficial for the liver 

Key Takeaways:

• Svetinorm is a bio-regulator peptide that has beneficial effects on the liver, such as supporting protein synthesis.

• When we have negative bacteria in our gut, that directly affects our liver detoxification pathways. By focusing on optimizing the health of our gut, we can lift some of the burden being put on our liver, and help support the detoxification process.

• By supporting gut health, you will indirectly support skin health, too. If you don't have the inflammation from the gut, then you're less likely to be inflamed in the skin.

Find more from Nathalie:

YouTube: https://www.youtube.com/channel/UCmholC48MqRC50UffIZOMOQ

Facebook Group: https://www.facebook.com/groups/biohackingsuperhumanperformance

Instagram: https://www.instagram.com/nathalieniddam/

Website: NatNiddam.com

Join Nat’s Membership Community: https://www.natniddam.com/bsp-community

Work with Nat: Book Your 20 MInute Optimization Consult: https://calendly.com/nniddam/intro-call?month=2021-08

Find more from Kyal Van Der Leest:

Website: www.lvlu

Did you know that the health of your microbiome affects your mental health, metabolism, and immune system? There's really no part of your body that's not affected by your microbiome health. 

I’m joined by Awais Spall, certified Functional Diagnostic Nutrition Practitioner. We’re discussing how he combines Ayurveda, Functional Medicine, and peptides to create a protocol that helps optimize the health of the microbiome. If you’re new to the system of Ayurveda, you’ll want to tune in as we deep dive into the definition of Ayurveda and the three doshas it consists of.

Awais Spall FDN-P is a Functional Medicine practitioner based out of Santa Monica, CA. Prior to becoming a health practitioner, Awais worked as a formulation chemist for various cannabis companies. As a product formulator, Awais combined his knowledge of formulation chemistry with his background in Ayurvedic Herbalism. Awais has inherited much of his knowledge around Ayurveda from his grandfather, who was a renowned herbalist in Pakistan.

In his practice at Integrative Oasis, Awais combines the cutting edge science of Functional Medicine with Ayurveda to address various gut health issues. 

What we discuss:

00:01:01 - What brought Awais to combine Ayurveda, Functional Medicine, and peptides

00:03:44 - The definition of Ayurveda

00:05:35 - The three elements of Ayurveda 

00:09:51 - Microbiome medicine 

00:13:48 - The microbiome and probiotics

00:18:22 - How nutrition is part of the microbiome 

00:25:56 - Tests for helping people with their microbiome medicine 

00:32:16 - What would a microbiome medicine protocol look like?

00:37:02 - The different forms lymphatic drainage 

00:43:52 - How peptides fit into Integrative Oasis

00:52:07 - How people could be using peptides wrong

00:57:34 - The art of microbiome medicine

Key Takeaways:

• The word Ayurveda is a conjugation of two words: 'ayus', meaning 'life' and 'veda', meaning 'science'. Ayurveda is defined as the science of how to live your life, and your mind, body, and spirit play a role in Ayurveda.

• The three doshas of Ayurveda are vata, kapha, and pitta. It is possible to be a combination of two or even all three of these doshas, and there are tests to determine which one a person is.

• Part of optimizing your microbiome health is reconditioning the gut by strategically weeding things out, and then taking probiotics appropriately. 

Find more from Nathalie:

YouTube: https://www.youtube.com/channel/UCmholC48MqRC50UffIZOMOQ

Facebook Group: https://www.facebook.com/groups/biohackingsuperhumanperformance

Instagram: https://www.instagram.com/nathalieniddam/

Website: NatNiddam.com

Join Nat’s Membership Community: https://www.natniddam.com/bsp-community

Work with Nat: Book Your 20 MInute Optimization Consult: https://calendly.com/nniddam/intro-call?month=2021-08

Find more from Awais Spall: