Can you imagine unlocking the secret to longevity through a powerful compound discovered on a remote island? 

 

In this episode of the Biohacking Superhuman Podcast, we chat with Dr. Ross Pelton, a renowned scientist and author, about rapamycin, a compound with untold potential for revolutionizing health and extending life. Together, we trace rapamycin’s fascinating history from its origins on Easter Island to its current potential as an awe-inspiring life-extending compound, delving into its dual mechanisms - mTOR and autophagy - for a fresh outlook on cellular metabolism and the aging process.

 

The intricate balance between mTOR and autophagy plays a pivotal role in achieving healthy longevity - a balance that our ancestors maintained effortlessly due to their lifestyle but has been upset by our modern way of living. With Dr. Pelton, we'll explore how to restore this equilibrium through intermittent fasting, exercise, a healthy diet, and of course, rapamycin. We also discuss the importance of dosing, frequency of use, and the intriguing concept of "rectangularization of the aging curve." 

 

Ross Pelton is a pharmacist, nutritionist, author and a health educator who is widely recognized as the world’s leading authority on drug-induced nutrient depletions. He was named one of the top 50 most influential pharmacists in the United States by American Druggist magazine for his work in Natural Medicine.

 

Visit  https://theantiaging.store/product/rapa-pro-rapamycin/ and use code longevity15 to save on your first order. 

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Website: NatNiddam.com

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Work with Nat: Book Your 20 Minute Optimization Consult: https://calendly.com/nniddam/intro-call?month=2021-08

 

Find more from Dr. Pelton:

 

Website: https://www.naturalpharmacist.net/ 

Book: https://www.amazon.ca/Rapamycin-mTOR-Autophagy-Treating-Syndrome/dp/1607660156 

What we discuss:

 

(0:00:03) - About Rapamycin

(0:13:03) - Balancing mTOR and Autophagy Importance

Could you imagine a condition that affects virtually every organ, eludes the standard diagnostic criteria, and causes multi-system inflammation? Meet the perplexing world of mast cell activation syndrome (MCAS). MCAS is an elusive condition that affects many, yet remains largely misunderstood. MCAS is a syndrome that triggers multi-system inflammation, and due to its diverse range of symptoms, it often eludes typical diagnostic processes. It has a profound impact on both the body and mind. Mast cells are integral to our innate immune system, playing a crucial role in safeguarding us against foreign invaders, allergens, and environmental toxins. However, potential triggers of mast cell hyperactivity can range from environmental toxins to mold.

 

Today I’m with Dr. Bruce Hoffman and we dissect this complex condition and delve into the critical role of mast cells in our immune system. Learn how mast cells, our body's fierce protectors against toxins, might turn hyperactive due to triggers like environmental toxins, heavy metals, or mold, launching a cell danger response that could send your body into a protective shutdown. The conversation takes a deeper turn as we explore the intersection of physical and mental health. Focusing on those battling MCAS and early developmental trauma, Dr. Hoffman shares invaluable self-regulation strategies and lends insight into the significance of neurofeedback and building a window of tolerance. 

 

Dr. Hoffman is board-certified and has a fellowship in anti-aging medicine as well as a Master’s degree in clinical nutrition. He is also a certified functional medicine practitioner. In addition to his clinical training, Dr. Hoffman has studied with many of the leading mind-body and spiritual healers of our times, including Deepak Chopra, Paul Lowe, Osho, Ramesh Balsekar, and Jon Kabat-Zinn. He has shared the stage with Dr. Deepak Chopra, Dr. John F. Demartini, and he continues to spread his inspiring vision of healing and wellness with audiences and patients around the world.

 

Thank you to our sponsors for making this episode possible:

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Find more from Dr. Bruce Hoffman:

Website: https://hoffmancentre.com/

 

What

As a nutritionist, I’ve always been fascinated by food and the power of food to heal our bodies. Over the last couple of years, the rhetoric around diets has been heating up–from keto to paleo to vegan, vegetarian, and now even carnivore. Diets are just lifestyles, so what is best?

 

Today I’m exploring this hot topic and sharing tips for adopting a new lifestyle or thinking about a new lifestyle and then applying it. Do your homework before making a dramatic diet change. It's vital to collect data about your health and I discuss the importance of baseline tests and how to measure and monitor your progress when changing dietary lifestyles. 

 

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Website: https://www.NatNiddam.com

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Work with Nat: Book Your 20 Minute Optimization Consult: https://calendly.com/nniddam/intro-call?month=2021-08

What we discuss:

11:14 - Discussion on Vegan and Carnivore Diets

20:17 - Baseline Testing for a Lifestyle Change

25:54 - Importance of Proper Guidance in Dietary Approaches

30:27 - Committing to Dietary Changes

35:58 - Optimal Diets and Lifestyle for Longevity

 

Key takeaways:

• There's not a one-size-fits-all approach when it comes to diet and nutrition. Dietary choices should be based on personal health status, lifestyle, and genetic makeup rather than blindly following popular trends or extreme diets.

• It’s important to test and collect data when making a diet change. It's advised to do blood work, assess micronutrient status, and examine the gut microbiome to get a clear picture of one's starting point. Monitoring body composition, such as getting a DEXA scan, is also suggested to measure progress.

• Long-term health and longevity are complex and cannot be solely attributed to a single dietary choice. Other lifestyle factors such as caloric restriction, periods of fasting, regular physical activity, and stress management are also crucial for promoting longevity.
  

Have you ever heard of heavy water?   In this episode of the Biohacking Superhuman Performance podcast, I chat with Victor Sagalovsky, Co-Founder and CEO of Litewater Scientific, about deuterium-depleted water. Deuterium is a naturally occurring isotope of hydrogen that has an extra neutron in its nucleus, making it twice as heavy as ordinary hydrogen, thus where it got its name of heavy water. Studies suggest that reducing deuterium levels in the body can have positive effects on various biological processes, such as improved cellular function, enhanced energy production, increased support of the immune system, and potential anti-aging properties.    Victor also shares how much deuterium we should have in our bodies, how long it takes to see results from drinking deuterium-depleted water, and who is most likely to experience the biggest shift in their health from intaking heavy water.   Victor Sagalovsky is the co-founder and CEO of Litewater Scientific, the first and only super deuterium-depleted light water, where he has dedicated himself to the research, development, and production of this rare water. Victor has researched and studied the benefits of deuterium-depleted water through his theory entitled Endogenous Radiation Damage Theory of Aging. It proposes that our biggest obstacle to longevity is the excess deuterium and other damaging isotopes on the planet and proper mitigation will radically extend our lifespans.      Thank you to our sponsors for making this episode possible:   Litewater : Use code NAT10 to save 10% at https://bit.ly/41BT7sR   Restoracell: Use code NAT25 at https://www.vitaliskincare.com/   Berkeley Life: Use code NIDDBL for 10% off at berkeleylife.com   LVLUP: Use code NAT10 to save 10% off at https://lvluphealth.com/  

What if your body could perform at superhuman levels using the power of science? The exploration of carbon 60's potential as a biohack for peak human performance presents an exciting frontier in health and wellness. This episode dives into the astounding world of Carbon 60 - a unique carbon allotrope that has the potential to push human performance to unprecedented heights.

 

Today I’m with Ian Mitchell, founder of Wizard Sciences, who created a world-class health and wellness research and development company. Our conversation dives into the remarkable properties of Carbon 60, investigating its role in reducing oxidative stress, increasing ATP production, detoxifying the body, inhibiting lipid peroxidation, and preventing rancidity. We delve into C60’s exciting emergence as a supplement, accompanied by Mitchell's groundbreaking innovations like Wizard Water, a hyper-oxygenated drink that has the potential in improving oxygenation and decreasing muscle fatigue. We also discuss the profound science behind waveform dynamics and quantum charging cells, as well as protocols to ensure carbon 60 is used beneficially and not as a detriment. 

 

As a research scientist and pharmaceutical consultant, Ian is Chief Science Officer at Redbud Brands and at HigherDOSE. He is Chief Science Advisor at Leela Quantum and is Scientific Advisor at Satori Neuro. Ian is also Polymath in Residence at Ecliptic Capital.

 

Thank you to our sponsors for making this episode possible:

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Find more from Ian Mitchell:
Website: https://wizardsciences.com/

Instagram: @wizardsciences

What we discuss:

Ready to challenge the current beliefs about meat consumption? There are current narratives that have demonized meat, explicating the healing powers of grass-fed pasture-raised meats for both our bodies and the planet. Today we’re debunking myths and misconceptions about meat consumption and its environmental impact.

 

I’m joined by Autumn Smith, and we’re discussing the potential of regenerative farming techniques, compared to conventionally raised beef. We navigate through the arguments against beef consumption and Autumn sheds light on how regenerative farming could be scaled to meet the needs of a growing population. We also discuss the critical role of humane treatment of animals in our food choices and reflect on our obligation as omnivores to respect the natural cycle of life.

 

Autumn Smith is the co-founder of Wild Pastures and Paleovalley, a company dedicated to helping people get the essential nutrients they need without added sugars, grains, or other harmful ingredients. She holds a Master of Science in Holistic Nutrition and is a Functional Diagnostic Nutrition Practitioner. She is also a certified eating psychology coach by the Institute of the Psychology of Eating and Soil Advocacy and is a doctoral candidate.

Thank you to our sponsors for making this episode possible:

Paleovalley: Use the link paleovalley.com/nathalie for 15% off.

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Work with Nat: Book Your 20 Minute Optimization Consult: https://calendly.com/nniddam/intro-call?month=2021-08

 

Find more from Autumn Smith:

Website: Paleovalley.com

Instagram: @paleovalley 

Link: paleovalley.com/promos/nathalie - 15% off (no code needed)

 

What we discuss:

(0:08:00) - Regenerative agriculture compared to conventionally raised meat

(0:13:00) - What is regenerative farming

(0:15:36) - Misconception of livestock environmental impact

(0:20:15) - Regenerative farming techniques for scale

(0:25:13) - Arguments against consuming animal products 

(0:28:00) - Narrative of consuming animal products

(0:35:47) - How eating animal products impacts health

(0:43:59) -

In recent years, there has been a significant change in how we approach and address diseases. Previously, the responsibility of maintaining good health largely relied on the healthcare system. However, this mindset has shifted, and individuals are now encouraged to play an active role in advocating for their own health. Understanding the biochemical processes that contribute to illnesses, such as Alzheimer's, has become crucial in managing and taking control of our personal health journey. By recognizing the intricate mechanisms that lead to diseases like Alzheimer's, we can make more informed decisions regarding our lifestyle choices, medical interventions, and preventative measures. 

 

I’m joined by Dr. Dale Bredesen, and we’re diving into the intricacies of Alzheimer's, its prevention, and even reversal possibilities. We cover the crucial role of the immune system in both Alzheimer's and COVID, and the fascinating connections between these diseases. Dr. Bredesen also discusses his lab's ground-breaking work to understand the neurodegenerative process, which has resulted in three books and thousands of people experiencing improvements in their conditions.

 

Dale E. Bredesen, M.D., is internationally recognized as an expert in the mechanisms of neurodegenerative diseases such as Alzheimer's disease, and the author of the New York Times bestsellers The End of Alzheimer's (Avery, 2017) and The End of Alzheimer's Program (Avery, 2020), as well as The First Survivors of Alzheimer’s (Avery, 2021). He has held faculty positions at UC San Francisco, UCLA, and the University of California San Diego, and directed the Program on Aging at the Burnham Institute before coming to the Buck Institute for Research on Aging in 1998 as its founding president and CEO. He is currently a professor at UCLA.

Thank you to our sponsors for making this episode possible:

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Work with Nat: Book Your 20 Minute Optimization Consult: https://calendly.com/nniddam/intro-call?month=2021-08

 

Find more from Dr. Dale Bredesen:

Website: https://www.apollohealthco.com/dr-bredesen/

Instagram: @drdalebredesen

Twitter: @drdalebredesen

 

What we discuss:

(0:00:03) - Shifting paradigms in 21st century medicine

(0:15:48) - Addressing toxi

Can you imagine a world where you're not bound by the inevitability of aging? These days it seems as though there’s a never-ending pursuit of immortality, but it’s important to question the quality of life that extended lifespans might offer. The secret to a longer, happier life may not solely lie in age-reversing technologies and biohacking techniques, but rather in our experiences and connections with the world.

 

I’m joined by Dr. Christopher Shade, and we’re diving into the realm of biohacking, self-care, and the prospects of reversing and embracing aging. From nutrition and detoxification to stem cells and peptides, we discuss the plethora of tools at our disposal to reverse the aging process. We also cover the practical implications of integrating one's consciousness into a machine, and why self-care and taking responsibility for our emotional health is essential. 

 

Dr. Christopher Shade, PhD, founder and CEO of Quicksilver Scientific®, specializes in the biological, environmental, and analytical chemistry of mercury in all its forms and their interactions with sulfur compounds, particularly glutathione and its enzyme system. Dr. Shade is regularly sought out to speak as an educator on the topics of mercury, environmental toxicities, neuroinflammation, immune dysregulation, and the human detoxification system in the United States and internationally. He has helped corporate executives, professional athletes, celebrities, children with autism, patients with chronic immune disorders and more. He strives to evolve the way the medical industry delivers care, and he is perpetually broadening the way the world understands health.

Thank you to our sponsors for making this episode possible:

QuickSilver Scientific: Use code NAT at https://glnk.io/zvxl/biohackingnat

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Whether you’re a professional athlete or someone who just wants to maintain muscle mass as you get older, mitophagy is a process we should all be focusing on. Prioritizing strategies that enhance mitophagy and promote muscle health can significantly contribute to a healthier and longer life. But what exactly can we do to promote mitophagy? Luckily, my guest today is an expert in the science of mitochondrial activation, and he’s sharing insights on the supplement that you need in your longevity routine.

 

I’m joined by Dr. Anurag Singh, and we’re diving into the realm of mitochondrial activation and its impact on muscle performance and health. We also shed light on the role of immunity in a healthy, long life, focusing on how mitochondrial health can rev up our immune systems. Dr. Singh also shares his insights on how mitochondrial health can influence skin health and reverse sun damage, and the development of topical formulations that can improve mitochondrial health in the skin.

 

Dr. Anurag Singh is the Chief Medical Officer at Timeline Nutrition. 

 

Thank you to our sponsors for making this episode possible:

 

Timeline is offering 10% off your first order of Mitopure. Go to timelinenutrition.com/NAT10 and use code NAT10 to get 10% off your order.

 

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Berkeley Life: Consumers may register and place an order using my code NIDDBL for 10% off at berkeleylife.com

Profound Health: Use code longevity15 to save 15% off your first order at https://profound-health.com/

 

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Work with Nat: Book Your 20 Minute Optimization Consult: https://calendly.com/nniddam/intro-call?month=2021-08

 

Find more from Dr. Anurag Singh:

Website: https://www.timelinenutrition.com/

Instagram: @timelinenutrition

 

What we discuss:

(0:00:00) - Mitochondrial activation and muscle performance

(0:12:13) - Revving up immune health through mitochondria

(0:15:24) - Mitochondrial health and immune function studies 

(0:21:06) - The benefits of high-dose vitamin c 

(0:26:20) - Skin aging and mitochondrial health

(0:27:53) - Topical formulation and skin health 

Did you know that hormones play a pivotal role in directing the course of your health throughout your lifetime? From physical growth and development to emotional well-being and reproductive health, these chemical messengers are vital for our overall well-being. Understanding how hormones function and seeking appropriate medical guidance can help us navigate through the various stages of life while maintaining hormonal balance.

 

Dr. Felice Gersh joins me as we take a closer look at the different types of estrogens, their individual impacts on the body, and the importance of understanding their nuances for overall health. We also discuss how reproduction is the prime directive of life and how hormones act as 'hormonal glue' to enable reproductive success. Plus, we dive into some of the benefits and complexities of Hormone Replacement Therapy (HRT), including when to start and the potential risks associated with it.

 

Dr. Felice Gersh is board-certified in both OB/GYN and Integrative Medicine. She is the founder and Medical Director of the Integrative Medical Group of Irvine. Always passionate about learning and education, she taught obstetrics and gynecology at Keck USC School of Medicine for 12 years as an Assistant Clinical Professor. Dr. Gersh now serves as an Affiliate Faculty Member at the Fellowship in Integrative Medicine, through the University of Arizona School of Medicine, where she lectures and regularly grades the case presentations written by the Fellowship students for their final exams. Dr. Gersh is a globally recognized expert on a wide range of female and integrative health topics. 

 

 

Thank you to our sponsors for making this episode possible:

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Work with Nat: Book Your 20 Minute Optimization Consult: https://calendly.com/nniddam/intro-call?month=2021-08

 

Find more from Dr. Felice Gersh:

Website: https://integrativemgi.com/

Instagram: @dr.felicegersh 

 

What we discuss:

(0:00:03) - The importance of women's hormones

(0:16:18) - Understanding the different types of estrogens

(0:20:05) - The effects of hormone therapy

(0:27:25) - Exploring hormone replacement and natural alternatives

(0:34:47) - The benefits of cyclical hormone therapy

(0:45:23) - Benefits of vaginal estrogen and hormone replacement therapy

(0:53:58) - The complexities of hormone replacemen