This week, Karl Byrne talks about the latest vaccination figures as well as other breaking COVID-19 news, including an exciting citizen science project where over the last year gamers playing EVE Online- a massively multiplayer online role-playing game, have carried out real world research that would have taken scientists over 330 years to complete.

In our main feature, Karl tells the incredible story of how the Pfizer-BioNTech is manufactured. The journey begins with a small, frozen tube of viral DNA in a facility in America's Midwest, involves travelling across states, and even continents, ending almost 2 months later with millions of doses of vaccine ready to be shipped to vaccination centres across the USA, Europe and beyond.

If you would like to get in contact with the team, or if you have a question you would like to ask our experts, you can email us: [email protected] 

Background music for the main feature is from MaxKoMusic

Who are the experts and groups around the world approving and regulating the new COVID-19 vaccines? And what do they need to consider amidst the urgency of vaccinating the world? In this episode ahead of World Immunization Week, Naomi Stewart speaks to Prof Annelies Wilder-Smith from the London School of Hygiene & Tropical Medicine. Prof Smith sits on WHO’s Strategic Advisory Group of Experts on Immunization, and walks us through the decisions involved in approving different vaccines - and how it could happen so quickly.

In this episode we explore the crucial stages of clinical trials and testing vaccines. How do clinical trials account for different demographics? How do we know vaccines are safe for everyone? We are joined by Dr Ed Parker, Research Fellow at the London School of Hygiene & Tropical Medicine and member of the Vaccine Centre. Ed walks us through the purpose of a clinical trial and its roots in ancient history, and provides insight behind LSHTM’s vaccine tracker.

Link to LSHTM short course on clinical trials: https://www.lshtm.ac.uk/study/courses/short-courses/clinical-trials

Vaccines have arguably made the greatest contribution to global health of any human intervention apart from the introduction of clean water and sanitation. With new vaccines being developed at an incredible rate to tackle the current pandemic, we take a look at how vaccines work and what goes into each shot.

Karl is joined by Helen Fletcher, Professor of Immunology at LSHTM, to take a look at what goes into a vaccine, how you design one and how the COVID-19 vaccines were created so quickly and safely. They also dispel some of the myths floating around about vaccines.

Professor Beate Kampmann, Director of the Vaccine Centre at LSHTM, also stops by to answer some questions sent in by you, our listeners.

You can find the video on vaccine safety that Karl and Beate talk about here.

Learn more about the Vaccine Centre here.

If you would like to get in contact with the team, or if you have a question you would like to ask our experts, you can email us: [email protected]

How did vaccines come to be and how have they changed over time? In today's episode, Naomi Stewart speaks to historian Dr Gareth Millward from the University of Warwick, on the history of vaccines and how vaccination programmes have evolved in the 20th century. Professor Liam Smeeth from the London School of Hygiene & Tropical Medicine then walks us through the vaccine landscape at the turn of the 21st century, and public perceptions and attitudes towards vaccination in a COVID-19 world.

Welcome back to a new season of LSHTM Viral, where we will be taking a deep-dive into vaccines and speak to experts working real-time on COVID-19. LSHTM modeller Roz Eggo reacts to the UK’s roadmap announcement on 22 February for easing lockdown restrictions, explaining the science behind the government's decision and how vaccination will forge a way out of the pandemic. John Edmunds, a UK government science advisor and professor of infectious disease at LSHTM discussed how new, potentially dangerous variants of the virus can emerge and key considerations for vaccination at this scale.

Launching February 23rd 2021

Vaccines are widely regarded as one of the greatest achievements of modern civilization, but how vaccines work, How do you create a vaccine? And perhaps most importantly, how do you produce enough to vaccinate the entire world?

Join Karl Byrne, Amy Thomas and Naomi Stewart every fortnight as they explore the latest developments in the COVID-19 pandemic and take a deep dive into vaccines and vaccinations.  They will be talking about the latest pandemic news, answering your vaccine questions and speaking to experts from LSHTM and beyond, as they explore the past, present and future of vaccines.

Find out more on our LSHTM podcast website.

How exactly did planetary health come to be, and where is it headed? In this season finale, we speak to two pioneers of the field - Prof Andy Haines of LSHTM and Richard Horton, editor of the Lancet. They discuss the urgency of embedding planetary health into the policy agenda, the benefits of increased public engagement with science during COVID-19, and how to address the inequalities that could hamper our efforts.

Welcome to a special episode of LSHTM Viral! The UK has become the first country in the world to approve the use of the Pfizer/BioNTech COVID-19 vaccine, with mass national roll out following as early as the next couple of weeks. Karl is joined in this episode by Dr Pauline Paterson, Dr Sadie Bell, and Prof Liam Smeeth of LSHTM, as they take a look at the factors that affect people's confidence and hesitance around vaccines, how the recent news might affect peoples perceptions of vaccines, and discuss some of the logistical and communication challenges that the UK faces in vaccinating the population.

If you would like to get in touch with your questions and comments, we'd love to hear from you!  You can email us: [email protected]

We hear a lot about reducing air pollution, but why do we need to? Join Amy, Naomi and Karl exploring the ins and outs of air pollution including, how the particles affect the human body, and where they come from. We turn to new research that uses machine learning, satellite data and on-the-ground monitors to build a highly detailed pollution map of Great Britain, revealing exciting avenues for the future of air pollution and health research. Contributions from LSHTM's Prof Paul Wilkinson and Prof Antonio Gasparrini.