Dr RR Baliga's "Got Knowledge Doc" Podkast

🫁💥 "Lung Clues & Blood Blues: How Tiny Lung Vesicles Spark Deadly Cancer Clots" 🧬🩸


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🩸 Summary:

Lung interstitial macrophages, activated by tumor-derived CXCL13, release integrin β2⁺ extracellular vesicles (sEVs) 🧬 that bind platelet GPIb 🧲, triggering clot formation across the body.

These sEVs are both a driver of cancer-associated thrombosis and a potential biomarker for early risk detection 🎯, offering safer, targeted therapeutic opportunities 💉.

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Dr RR Baliga's "Got Knowledge Doc" PodkastBy Dr RR Baliga, MD, MBA

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