Want to change the world but feel like you cannot? Manilius thought the same.

Quis tantum mutare potest sine numine fati?

Who can change so much without the will of fate?

Quis (who) is an interrogative pronoun.

Tantum (so much or "so greatly) is an adverb modifying "mutare."

Mutare (to change or to alter) is in the present active infinitive form.

Potest (can) is the third person singular present active indicative of "posse," meaning "to be able" or "can."

Sine (without) is a preposition.

Numine (god or divine power) is the ablative singular form of "numen," meaning "divine will."

Fati (of fate) is the genitive singular form of "fatum," meaning "fate" or "destiny."