In hour 1 of The Mark Reardon Show, Mark celebrates NBC firing Joy Reid. He discusses the recently released information on multiple intelligence agency employees involvement in sex chats, and more. Mark is then joined by Kimberley Strassel, a columnist and editorial board member for the Wall Street Journal. They discuss her latest piece which is headline, "Trump's Constitutional Cleanup" and more. He later reviews Megan Lynch's (KMOX News Talent) interview with the St Louis Mayor, Tishaura Jones. They play audio from the interview and discuss some of the mayor's comments. In hour 2, Sue hosts, "Sue's News" where she discusses the latest trending entertainment news, this day in history, the random fact of the day, and more. Mark is then joined by Pete Sepp, the President of the National Taxpayers Union. They discuss why congress needs to stop what he calls the "Misguided" IRS relations hiring small businesses. They also discuss his thoughts on tariffs and the harm they could cause US citizens if put into effect. He is later joined by KSDK Sports Director Frank Cusumano who discusses the Cardinals first victory of the spring, the Blues solid start following the midseason break, Mizzou's weekend loss, and more. In hour 3, Mark is joined by John Sailer, the Director of the Higher Education Policy and a Senior Fellow at the Manhattan Institute. They discuss his latest piece in the City Journal which is headlined, "How Universities Get Away with Hiring Radicals" and more. Mark is later joined by Dan O'Neill, a sports journalist and a local author. They discuss his latest piece on danoneill.net headlined, "Arenado Situation Shows Baseball's Lost Soul" and more.