This document provides a clinical consensus statement from the European Society of Cardiology Working Group on Cardiovascular Surgery and the European Association for Cardio-Thoracic Surgery Coronary Task Force outlining best practices for the intra-operative and post-operative management of conduits used for coronary artery bypass grafting. The authors review the scientific evidence behind various techniques and medications used to preserve the integrity of arterial and vein grafts used for CABG surgery. They discuss the importance of appropriate harvesting techniques, storage solutions, and antithrombotic and lipid-lowering therapies. The authors also highlight gaps in knowledge and suggest future research directions to improve the long-term patency and efficacy of CABG conduits.