Medical Digest & Congress Report

Professor Hope S. Rugo discusses the final overall survival results from the Phase 3 CAPItello-291 trial, evaluating the efficacy, long-term disease control, and safety of combining the AKT inhibitor capivasertib with fulvestrant for patients with AI-resistant, HR+/HER2− advanced breast cancer.

Video: https://medicaldigest.org/scientific-contents/interview:capitello-291-trial-final-overall-survival-results-capivasertib-and-fulvestrant-hrher2-advanced-breast-cancer

Professor Meryam Schouler-Ocak provides an expert overview of the most impactful discussions, clinical updates, and essential takeaways from the 2026 EPA Congress, exploring the latest advancements and future directions in psychiatric research and practice.

Video: https://medicaldigest.org/scientific-contents/interview:highlights-and-key-takeaways-2026-epa-congress

Professor Mardi Gomberg-Maitland presents the results from the Phase 2 CADENCE trial, investigating the efficacy and safety of Sotatercept in patients with combined post- and pre-capillary pulmonary hypertension associated with heart failure with preserved ejection fraction (HFpEF).

Video: https://medicaldigest.org/scientific-contents/interview:efficacy-and-safety-sotatercept-ph-hfpef-results-phase-2-cadence-trial

Professor Geoffrey D. Barnes examines the therapeutic innovations introduced in the new ACC 2026 Acute Pulmonary Embolism Guideline, focusing on updated treatment protocols and novel anticoagulation strategies presented at the ACC 2026 Annual Congress.

Video: https://medicaldigest.org/scientific-contents/interview:therapeutic-novelties-new-acc-2026-acute-pulmonary-embolism-guideline

Dr. Stephen Thomas examines the evolving role of human challenge models in vaccine development, debating whether they represent a new gold standard for establishing efficacy and safety at the World Vaccine Congress Washington 2026.

Video: https://medicaldigest.org/scientific-contents/interview:human-challenge-models-new-gold-standard

Professor Asimenia Angelidou discusses the INSIS Metacohort Vaccine Safety Study, establishing a new paradigm for profiling clinical and immune adverse events following immunization (AEFI) at the World Vaccine Congress Washington 2026.

Video: https://medicaldigest.org/scientific-contents/interview:insis-metacohort-vaccine-safety-study-paradigm-clinical-and-immune-aefi-profiling

Dr. Yurong Fei-Bloom explores the essential strategies for fostering public confidence in immunization by prioritizing transparency and leveraging technological advancements at the World Vaccine Congress Washington 2026.

Video: https://medicaldigest.org/scientific-contents/interview:building-future-vaccine-trust-through-transparency-and-innovation

Dr. Richard Hughes IV examines the shifting landscape of immunization mandates and public health legislation, questioning whether the heightened demand for safety proof is becoming the new standard for vaccine policy at the World Vaccine Congress Washington 2026.

Video: https://medicaldigest.org/scientific-contents/interview:prove-its-safe-new-vaccine-policy-norm

Dr. Bill Hausdorff explores the complex dynamics of combining respiratory vaccines, focusing on how to optimize clinical efficacy and long-term durability while streamlining complex immunization schedules at the World Vaccine Congress Washington 2026.

Video: https://medicaldigest.org/scientific-contents/interview:combining-respiratory-vaccines-balancing-efficacy-durability-and-immunization-schedules

Professor Joo-Yong Hahn presents critical insights on the discontinuation of beta-blocker therapy in stabilized patients following an acute myocardial infarction, discussing the clinical implications and trial findings at the ACC 2026 Annual Congress.

Video: https://medicaldigest.org/scientific-contents/interview:discontinuation-b-blocker-therapy-stabilized-patients-after-acute-myocardial-infarction