Medicine Made Simple episodes:

• November 25, 2025Ganong’s Review of Medical Physiology

  A comprehensive medical physiology textbook, beginning with a dedication to the influential scientist and educator William Francis Ganong. The text meticulously covers fundamental biological concepts, including cellular organization, fluid compartments, and molecular mechanisms like protein synthesis and the citric acid cycle. Subsequent chapters systematically explore the function of major organ systems, focusing on neurophysiology, muscle excitation and contraction, the immune system, the special senses (vision, hearing, taste), and the endocrine system, which includes detailed discussions on hormone regulation, metabolism, and reproductive physiology. Finally, the content addresses gastrointestinal, cardiovascular, and renal physiology, examining topics such as digestion, blood flow regulation, respiration, and acid-base balance in both normal and pathological states.
  
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• November 25, 2025Prosthodontic Treatment for Edentulous Patients: Complete Dentures and Implant-Supported Prostheses

  A comprehensive overview of the field of complete dentures and prosthodontics, focusing on the restoration and rehabilitation of edentulous patients. It details the history and current role of complete dentures, acknowledging their limitations compared to natural dentition, while also covering contemporary implant-supported prostheses as a superior alternative for long-term stability and function. The material addresses numerous clinical and technical considerations, including impression materials and techniques, the proper selection and arrangement of artificial teeth for optimal esthetics and occlusion, and the fabrication of dentures using various resin and metal alloys. Furthermore, the text explores biological factors influencing denture success, such as the condition of the oral mucosa, salivary function (including issues like xerostomia), and the management of complications like temporomandibular disorders (TMDs) and post-surgical defects (obturators).
  
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• November 25, 2025Applied Physiology in Intensive Care Medicine - Second Edition

  Focuses on critical care physiology and monitoring techniques, providing extensive information on the mechanics of mechanical ventilation and its complications, such as intrinsic Positive End-Expiratory Pressure (PEEP) and ventilator-induced lung and diaphragm injury. Chapters address complex topics like pulmonary gas exchange, using methods such as the multiple inert gas elimination technique (MIGET) and the challenges of measuring dead space and shunt, as well as the evaluation of hemodynamics and fluid responsiveness through techniques like pulse pressure variation and passive leg raising. Furthermore, the text explores the impact of conditions like sepsis and acute neurological injury on various organ systems, including the pulmonary endothelium, heart, and kidneys, while discussing the application and limitations of different clinical severity scores and monitoring tools.
  
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• November 25, 2025Reproductive Physiology in Plants

  Presents several specialized research papers on plant reproductive biology. The book itself covers diverse topics such as the effects of herbivory, plant genes and hormones, and functional diversity. The included studies detail the genetic mechanisms of flowering in strawberries, the influence of fragmentation and herbivory on plant reproductive traits and diversity in various ecosystems, and the molecular regulation of male and female gamete specification and guidance in Arabidopsis thaliana. Additionally, a comparative analysis explores the correlation between pollen ornamentation and pollination type in Araceae and Arecaceae, while another piece examines how life history traits influence selfing versus outcrossing in annual plants. Overall, the sources illustrate cutting-edge research across the cellular, genetic, ecological, and evolutionary facets of plant reproduction.
  
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• November 25, 2025Guyton and Hall Physiology Review

  A publication intended as a self-assessment tool for students studying medical physiology. The excerpts feature numerous multiple-choice questions and detailed explanations of the answers covering a vast range of physiological topics. Specifically, the material addresses cellular and molecular physiology, cardiovascular dynamics (including blood flow, heart function, and shock), renal function and fluid balance (including acid-base and electrolyte disorders), hematology and immunology, respiration, and neurophysiology and sensory systems. It also contains sections on gastrointestinal, endocrine, and reproductive physiology, as well as metabolism and sports physiology, often presenting clinical scenarios and associated laboratory values for students to interpret.
  
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• November 25, 2025Applied Physiology in Intensive Care Medicine - Third Edition 2

  A broad spectrum of critical care topics. Several articles discuss cardiopulmonary dynamics, including right ventricular function under positive pressure ventilation, the management of pulmonary complications following subarachnoid hemorrhage, and the use of permissive hypercapnia as a protective ventilatory strategy. A significant portion of the text addresses hemodynamic monitoring and resuscitation in critically ill patients, exploring techniques to assess fluid responsiveness, different methods for measuring intra-abdominal pressure (IAP), and the pathophysiology of septic shock, including vascular hyporesponsiveness. Finally, there are dedicated sections on the importance of sleep quality in the intensive care unit, the monitoring of peripheral perfusion and oxygenation, and the evolving understanding of ventilator-induced diaphragmatic and lung injury (VIDD/VILI).
  
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• November 25, 2025Applied Physiology in Intensive Care Medicine - Third Edition 1

  A comprehensive overview of critical care medicine, focusing heavily on pulmonary physiology and monitoring techniques. Key topics include mechanical ventilation strategies such as managing intrinsic PEEP and optimizing breath patterns, as well as complex gas exchange concepts like dead space measurement and the Multiple Inert Gas Elimination Technique (MIGET). Furthermore, the sources explore hemodynamic monitoring methods like cardiac output measurement (e.g., lithium dilution, bioreactance) and assessing fluid responsiveness, alongside discussions on neuromonitoring (e.g., ICP, transcranial Doppler) in traumatic brain injury. Finally, there is significant attention given to sepsis management, scoring systems, and the long-term outcomes associated with goal-directed therapy.
  
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• November 25, 2025Physical Examination & Health Assessment

  Focusing on physical assessment and clinical skills. The content is organized by body system chapters (e.g., Ear, Nose, Mouth, Throat, Breasts, Abdomen, Musculoskeletal System), detailing components like Structure and Function, Subjective Data (patient history), Objective Data (examination findings), Health Promotion and Patient Teaching, and discussions of Abnormal Findings. Beyond physiological assessment, the material emphasizes crucial professional practices, including the nursing process, critical thinking, culturally competent care (addressing demographics and health-related beliefs), specialized interview techniques for different populations (e.g., infants, older adults), and screening for issues like violence, substance abuse, and common mental health problems. The text also includes copyright and liability notices, as well as biographical information highlighting Dr. Jarvis's contributions to nursing education.
  
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• November 25, 2025Anatomy and physiology for Health Professionals

  Cover essential biological levels of organization, starting with cellular biology, then detailing tissue types (epithelial, connective, muscle, and nervous) and their associated pathologies. Major content areas include the skeletal and muscular systems, followed by in-depth explanations of the nervous, endocrine, cardiovascular, lymphatic, respiratory, urinary, and digestive systems, often discussing related diseases and homeostatic imbalances. Furthermore, the text explores special senses, the reproductive system including fetal development, and fundamental concepts of genetics and heredity, presenting information with learning goals, review questions, and critical thinking exercises.
  
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• November 23, 2025Grant’s Dissector

  A laboratory manual for human anatomy dissection. The source provides comprehensive dissection instructions organized by body region, including the head, neck, thorax, abdomen, pelvis, perineum, and upper and lower limbs, often noting key features and modifications in the latest edition, such as new approaches to abdominal and head dissections. Additionally, the manual lists the work's authors and contributors, offers a publisher disclaimer concerning medical verification, and defines fundamental anatomical terminology and dissection techniques used throughout the text, such as blunt and sharp dissection and various instrument uses. Scattered throughout the procedural steps are clinical correlations to link the anatomical structures to medical practice, for example, regarding portal hypertension or ankle injuries.
  
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