Ch17 focuses on understanding and managing substance use disorder, emphasizing its prevalence and impact in the United States. It outlines the objectives for learning about various abused substances, including identification, signs, symptoms, and treatment for withdrawal. The text also provides a key terms glossary and discusses the nursing process for assessing, planning, implementing, and evaluating care for patients with these disorders. Specifically, it addresses opioids, stimulants, depressants, alcohol, and nicotine, detailing their mechanisms, effects, indications, adverse effects, and management of withdrawal and overdose. The chapter highlights the importance of patient-centered care, especially for adolescent and older adult populations, and includes information on relevant organizations and agencies.