A third challenge is brought against the ruling of Raba bar Avuha, which posits that one who vows to bring "an ox from my oxen" must provide his best ox. The difficulty arises from a comparison to commercial law: if a person sells "a house among my houses," they are not legally obligated to provide the buyer with their finest property. This discrepancy is resolved by distinguishing between the laws of hekdesh (consecration to the Temple), where the Sanctuary maintains the "upper hand," and the laws of sales, where the seller retains the "upper hand."

If an individual vows to bring an offering to the Temple of Onias in Egypt, the fulfillment of that vow depends on its specific phrasing. Generally, if the vow was intended for a Temple for God, the offering must be brought to the Temple in Jerusalem; however, if the vow was specific to the Temple of Onias, there is a dispute as to whether the offering is considered a sacrifice and would be punished by karet or if the person has merely committed a "meaningless" act.

A kohen who served at the Temple of Onias and subsequently repents is barred from performing service in the Temple in Jerusalem. This was a penalty to such priests, categorizing them as equivalent to a blemished kohen; while they are disqualified from performing the sacrificial service, they are still permitted to eat and share in the distribution of the sacrificial foods (kodashim) with their fellow priests.

Likewise, a kohen who served in idolatrous worship is disqualified from serving in the Temple. Rav Nachman and Rav Sheshet debate four specific scenarios to determine if they constitute "serving" an idol and whether a priest who performed them can return to Temple service. These four cases are: slaughtering an animal to an idol intentionally, sprinkling the blood unwittingly, bowing down to the idol, and accepting the idol as a god by verbal declaration.

A fundamental debate exists between Rabbi Meir and Rabbi Yehuda regarding the nature of the Temple of Onias itself - specifically, whether it was established for worship of God or for idolatry. Each Sage cites a different historical tradition regarding the political and family disputes that led Onias to flee to Egypt and build his Temple.