This podcast covers the cellular uses of cholesterol and a brief summary of its biosyntthesis and its regulation by intracellular levels of cholesterol.

Check out the podcast on regulation of HMG CoA reductase below:

https://youtu.be/FNSr3G6OTBs?si=da3V5SkXGkM8STsZ

Also check out how statins reduce plasma cholesterol below:

https://youtu.be/HrwI02Ww3Ew

Also check out the he complete podcast on Regulation of Cholesterol Biosynthesis below:

https://youtu.be/K1i3P3KPN3g

Amino acids can be classified as essential or non- essential. They can also be classified by the carbon skeletons they produce during catabolism. These carbon skeletons can be either glucogenic or ketogenic.

A Summary of Metabolism & Its Regulation :This podcast summarizes metabolism and its regulation by hormones. It includes: 1. Definition of metabolism, catabolism, anabolism, and their cellular compartments; 2. The 3 stages of catabolism; 3. The major cellular uses of glucose, amino acids, fatty acids, and cholesterol; 4. The major metabolic pathways that produce energy from dietary carbohydrates and fat; 5. Comparison of the energy (ATP) output from catabolism of glucose , fatty acids, and acetoacetate (ketone bodies); 6. Hormonal regulation of the major metabolic pathways by insulin, glucagon, and epinephrine

This podcast covers some misconceptions about catabolism of glucose , fat (Triacylglycerol) and amino acids. it also compares the energy output from these three dietary components.

This podcast covers the major tissue effects of insulin and glucagon in the well-fed state and the fasting state, respectively. The key effects of these hormones on carbohydrate, fat, and protein metabolism in various tissues are summarized.

Cell-Cell Communication is a fundamental process that is essential for the regulation of metabolism in various organs. Through hormones of the endocrine system, signals are chemically transmitted through the bloostream between different organs. The outcome of a hormone binding its specific receptor in target tissues can produce profound effects on metabolism. Insulin and its effects on the liver, is used as an example of the outcome of communication between the pancreas and the liver.

This podcast covers the catabolism of alanine, glutamate and aspartate, including the roles of 3 important enzymes alanine transaminase (ALT), aspartate transaminase (AST) and glutamate dehydrogenage in this process. Input of nitrogen into the Urea cycle is provided directly or indirectly through the metabolism of the 3 discussed amino acids.

This podcast is an overview of the catabolism of amino acids including the initial phase of transferring amines through transaminases to an acceptor keto acid like Alpha-ketoglutarate to produce glutamate.

During fasting, fatty acids are mobilized from stored triacylglycerol in adipose tissue through the activation of Hormone-Sensitive Lipase by epinephrine which results in the release of 3 fatty acids to the bloodstream.

This podcast covers three misconceptions dietary fat and covers the crucial contributions of dietary fat to energy production/ storage, membrane synthesis, and inflammation. The key roles of cholesterol in cellular functions are also summarized.