This episode is a deeply personal reflection on coping with issues surrounding mental health as a student in STEM, particularly as a PhD student in a research lab. I identify several sources of anxiety and depression which are often felt by students in research laboratories, whether or not the PI is actively promoting a toxic work environment. I then discuss my own struggles with anxiety, which manifested in many physiological forms, some of which required intervention. These included cardiac arrhythmias, temporomandibular joint disorder, hyperhydrosis, and high blood pressure. While I offer some words of encouragement and concrete strategies one can use to cope with anxiety and depression, I urge any listener or viewer to seek the services of professionals on or off campus.