How do you run clinical trials that maximise the efficiency for patients, clinicians and drugs developers? That's the challenge being addressed by world's largest ever clinical trial of Parkinson's medications. To discuss this new, and potentially extremely effective, way of runnings multiple trials simultaneously, the Movers & Shakers are joined at the pub by some of the core team from the project, who answer their questions and consider whether this represents the future of clinical trials.

This special episode is sponsored by Cure Parkinson's.

Presented by Rory Cellan-Jones, Gillian Lacey-Solymar, Mark Mardell, Paul Mayhew-Archer, Sir Nicholas Mostyn and Jeremy Paxman.

Produced and edited by Nick Hilton for Podot.

Sound mixing by Ewan Cameron.

Music by Alex Stobbs.

Hosted on Acast. See acast.com/privacy for more information.

So, after two long years of campaigning, this week the Parky Charter – our set of demands for the government – had its moment in Parliament. With the Movers & Shakers and other supporters in attendance, MPs debated the need for improved care for people with Parkinson's across the UK. But what were the important moments from the debate? What wasn't mentioned? And where do we go from here? To celebrate how far we've come and mull over our next steps, the gang gathered back at Gillian HQ (though she was regrettably laid up with a fever) where the Parky Charter was first conceived, back in the winter of 2023.

Sponsored by Albion Chambers.

Presented by Rory Cellan-Jones, Gillian Lacey-Solymar, Mark Mardell, Paul Mayhew-Archer, Sir Nicholas Mostyn and Jeremy Paxman.

Produced and edited by Nick Hilton for Podot.

Sound mixing by Ewan Cameron.

Music by Alex Stobbs.

Hosted on Acast. See acast.com/privacy for more information.

This week, the Movers & Shakers are joined in the pub by our friends from Cure Parkinson's and Parkinson's UK. They are two of the charities working so hard to find ways of dealing with Parkinson's and improving the lives of those with the condition. But they also face huge challenges. Is enough being invested in research? Are the charities forced to compete with one another for limited resources? And what is the rule of the Michael J. Fox Foundation, the huge American body that operates at a much larger scale than its UK counterparts? We're talking about all this – and more! – on today's episode.

It's not too late to write to your MP ahead of next Monday's debate – you can do so here.

Sponsored by Albion Chambers.

Presented by Rory Cellan-Jones, Gillian Lacey-Solymar, Mark Mardell, Paul Mayhew-Archer, Sir Nicholas Mostyn and Jeremy Paxman.

Produced and edited by Nick Hilton for Podot.

Sound mixing by Ewan Cameron.

Music by Alex Stobbs.

Hosted on Acast. See acast.com/privacy for more information.

We try not to shy away from the less cheerful topics here on Movers & Shakers, and this week we're once again looking at depression. We're joined in the pub by a top expert – Professor Dag Aarsland – to look at how depression affects Parkies, whether there's something specific about the condition that causes it, and what responses are available. As ever, this is a candid chat that gets to the heart of a matter which is too often left silent.

If you'd like to download a template for writing to your MP, you can find one here.

Sponsored by Albion Chambers.

Presented by Rory Cellan-Jones, Gillian Lacey-Solymar, Mark Mardell, Paul Mayhew-Archer, Sir Nicholas Mostyn and Jeremy Paxman.

Produced and edited by Nick Hilton for Podot.

Sound mixing by Ewan Cameron.

Music by Alex Stobbs.

Hosted on Acast. See acast.com/privacy for more information.

Let there be light! Well, certain types of light, at least. That's what we're discussing down at the Movers and Shakers Arms today, where the gang are joined by Professor Glen Jeffery, an expert in the use of light therapies. Why are some lights – like infrared – good for us, whilst others – like UV – are bad? How does light impact on our mitochondria? And, most importantly, what does any of this have to do with Parkinson's?! Join us for a fascinating dive into a less-discussed, but possibly very important, piece in the puzzle of searching for a PD disease modifier.

If you'd like to download a template for writing to your MP, you can find one here.

Sponsored by Albion Chambers.

Presented by Rory Cellan-Jones, Gillian Lacey-Solymar, Mark Mardell, Paul Mayhew-Archer, Sir Nicholas Mostyn and Jeremy Paxman.

Produced and edited by Nick Hilton for Podot.

Sound mixing by Ewan Cameron.

Music by Alex Stobbs.

Hosted on Acast. See acast.com/privacy for more information.

Over the summer months, we at Movers & Shakers HQ ran a competition: the local group who acquired the most signatures towards the Parky Charter petition would get their own special episode. And here it is, with the superstars from the Bexhill and Battle area, who acquired a whopping 573 signatures! Three of them joined the Movers & Shakers in the pub, and we also speak to the TikTok poet whose viral video spurred the campaign on. But most importantly, this episode contains important instructions on what you – yes: you! – need to do next. Write to your MP, share your experience, and urge Britain's politicians to give this debate proper consideration.

If you'd like to download a template for writing to your MP, you can find one here.

Sponsored by Albion Chambers.

Presented by Rory Cellan-Jones, Gillian Lacey-Solymar, Mark Mardell, Paul Mayhew-Archer, Sir Nicholas Mostyn and Jeremy Paxman.

Produced and edited by Nick Hilton for Podot.

Sound mixing by Ewan Cameron.

Music by Alex Stobbs.

Hosted on Acast. See acast.com/privacy for more information.

There are few great anxiety inducers for Parkies than the prospect of having a fall. Squeezed into the Notting Hill pub – having dodged bustling waiters, stray chair legs and a labyrinthine tangle of cables – the Movers & Shakers are joined by two experts, Laura Douglas from Neuro Heroes and the University of Exeter's Dr Will Young, to discuss the reality of falls. Are people with Parkinson's at greater risk? And, if so, what can we do to a) prevent falls, and b) mitigate the seriousness? Navigating our way, ever so carefully, through this issue should shine a light on how to stay safe and help your loved ones.

A note for listeners: Will Young and his team are currently running a research project looking at the psychological impact of various potential symptoms of Parkinson's. The aim is to validate a new questionnaire (the Lo-Co-Motion) that could be used as part of training/therapies for managing symptoms and any associated anxiety. This in an online survey that takes about 30-50 minutes. Further information and the online survey can be found here. 

Sponsored by Albion Chambers.

Presented by Rory Cellan-Jones, Gillian Lacey-Solymar, Mark Mardell, Paul Mayhew-Archer, Sir Nicholas Mostyn and Jeremy Paxman.

Produced and edited by Nick Hilton for Podot.

Sound mixing by Ewan Cameron.

Music by Alex Stobbs.

Hosted on Acast. See acast.com/privacy for more information.

On today's Movers & Shakers, we're putting down our pints and rolling a joint talking about how cannabis could be an important part of Parkinson's treatment. Subject to stigma over its use, have we been ignoring the therapeutic qualities of the plant? To discuss this, we talk to Professor Mike Barnes, a world expert in medical cannabis, and hear from many of our listeners who have dabbled with the various strains. With uses for everything from pain to sleep, this is an in-depth look at a much-maligned treatment option.

Sponsored by Albion Chambers.

Presented by Rory Cellan-Jones, Gillian Lacey-Solymar, Mark Mardell, Paul Mayhew-Archer, Sir Nicholas Mostyn and Jeremy Paxman.

Produced and edited by Nick Hilton for Podot.

Sound mixing by Ewan Cameron.

Music by Alex Stobbs.

Hosted on Acast. See acast.com/privacy for more information.

Can you hide your Parkinson's? And should you? Those are the questions we're tackling today, as we're joined in the pub by Rob Burley, a former BBC producer and author of Why Is This Lying Bastard Lying to Me?, a book about the lost art of the political interview. After his PD diagnosis, Rob went on television and found himself subjected to unfortunate social media feedback. Do we always know when it's time to reveal a diagnosis? And can you really keep things private as symptoms set in? This candid chat explores the difficult reality, especially for people still in the workforce.

Sponsored by Albion Chambers.

Presented by Rory Cellan-Jones, Gillian Lacey-Solymar, Mark Mardell, Paul Mayhew-Archer, Sir Nicholas Mostyn and Jeremy Paxman.

Produced and edited by Nick Hilton for Podot.

Sound mixing by Ewan Cameron.

Music by Alex Stobbs.

Hosted on Acast. See acast.com/privacy for more information.

This week, we're issuing a special episode to remember the life of John Stapleton, who died last week. We were privileged to have John join us in the pub earlier this year to discuss his life, career and PD journey. From getting pecked off our screen's by Rod Hull's intemperate Emu to making a film about his diagnosis with his award-winning documentarian son Nick, John led an extraordinary life. In this episode, we reflect on what made him a great presenter and a superb advocate for people with Parkinson's, and replay our conversation with him.

Presented by Rory Cellan-Jones, Gillian Lacey-Solymar, Mark Mardell, Paul Mayhew-Archer, Sir Nicholas Mostyn and Jeremy Paxman.

Produced and edited by Nick Hilton for Podot.

Sound mixing by Ewan Cameron.

Music by Alex Stobbs.

Artwork by Till Lukat.

PR by Sally Jones.

Hosted on Acast. See acast.com/privacy for more information.