🫀 Scar. Signal. Survival.

A major new JAMA study from the NHLBI Hypertrophic Cardiomyopathy Registry followed 2,698 patients for nearly 7 years and demonstrated that advanced cardiac magnetic resonance imaging and NT-proBNP markedly improve prediction of adverse outcomes in hypertrophic cardiomyopathy.

📌 Key findings: • Late gadolinium enhancement (fibrosis burden) strongly predicted events • LGE ≥9% of LV mass substantially increased risk • LV mass index, LV systolic dysfunction, and NT-proBNP independently predicted outcomes • Traditional markers alone may miss important risk signals

This work moves HCM risk assessment beyond simple wall thickness toward a multidimensional precision cardiology approach.

📖 JAMA. Published online May 11, 2026. #Cardiology #HCM #HypertrophicCardiomyopathy #CardiacMRI #CMR #HeartFailure #SuddenCardiacDeath #PrecisionMedicine #CardioTwitter #JAMA