Naked Genetics, from the Naked Scientists

By Phil Sansom

Natural Sciences Medicine

What's Naked Genetics, from the Naked Scientists about?

From plants to pathogens, fruit flies to fungi and hamsters to humans, Naked Genetics takes a look at the science of genes. With in-depth interviews, the latest news from the world of genetics, answers to your questions, and our gene of the month, tune in for a look inside your genes...

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LAST EPISODE

FOXG1 Syndrome: Fighting th...

02.20.2020

Listener Vivek got in touch with a question about a rare genetic disease his son has, called FOXG1 Syndrone. In fact, it's so rare - and so newly-discovered - that only about six hundred people in the world have been ...

Naked Genetics, from the Naked Scientists episodes:

02.20.2020 FOXG1 Syndrome: Fighting the Odds Listener Vivek got in touch with a question about a rare genetic disease his son has, called FOXG1 Syndrone. In fact, it's so rare - and so newly-discovered - that only about six hundred people in the world have been ...
01.14.2020 The Fly Infest-agation We got a Christmas present from listener Anna: a small plastic tube full of dead flies. They've recently been infesting the hospital where she works. She wants us to figure out what they are, and what caused the infestation. Can ...
12.14.2019 African genetics and ethics There are very few African studies in genetics. And on the whole, there is a big European bias in the field. In Europe there are resources of hundreds of thousands of individuals' data, like the UK Biobank, and so that's ...
11.14.2019 What's in the water? This month we're diving into the stuff that makes up two thirds of the Earth's surface. Can you use genetics to figure out what's in the water? We put the science to the test by making a geneticist guess our ...
10.14.2019 Quadrillions: Sequencing the UK Biobank Half a million genomes. That's how many the UK Biobank has, stored as blood samples in freezers up in Manchester. And in September 2019 they announced a project to sequence every single one of them. It's the obvious next step ...
09.14.2019 The Dog Show It's a doggy dog world... in this episode we're talking pugs, bulldogs, and French bulldogs. They've all been bred for flat faces, but their airways haven't shrunk alongside their skulls - meaning that they often struggle to breathe. How has ...
08.14.2019 Mendel's Trick Naked Genetics is back with new episodes every month! Today we're taking a step back. Where does genetics actually come from? How did we get to today's world of genome sequences and gene editing? It all started with a 19th-Century ...
03.24.2019 Decoding a Mammoth with George Church Join Harvard DNA pioneer George Church and Chris Smith in conversation as they discuss gene cloning, DNA sequencing, decoding the mammoth genome, the risks posed by fossil viruses lurking in extinct genomes, the prospects of xenotransplantation and safety of gene ...
12.21.2018 The CRISPR baby controversy In November, He Jiankui claimed that two genetically engineered children have been born. Did he really do it? And if so, what are the ramifications for the babies and for the field? Georgia Mills explores the controversy in a special ...
04.13.2018 The future of forensic genetics We're returning to the scene of the crime with another look at the latest techniques in the world of forensic genetics - can we really predict physical features or even ethnicity from your DNA, and what does this mean for ...
03.14.2018 A Festival of Genomics We're off to a festival - but before you worry about where your tent and wellies are, it's the Festival of Genomics, held at a clean and dry conference centre in London rather than a muddy field full of rock ...
02.14.2018 Crime scene genes It's CSI Naked Genetics, as we find out how genetic technology is used to solve crimes. Like this podcast? Please help us by supporting the Naked Scientists
01.14.2018 Back to the womb We take a trip back to the womb and before, to find out about early development. Plus, the importance of placentas, why the age of your womb rather than your eggs matters, and a video game-inspired gene of the month. ...
12.14.2017 The future of genomic medicine This month we're finding out how genetic advances are shaping the future of healthcare at the Genetics Society autumn meeting. Plus, signposts for bees and an operatic gene of the month. Like this podcast? Please help us by supporting the ...
11.14.2017 Matchmaking at the zoo This month we're off to the zoo to meet some lovelorn laughing thrushes, endangered snails, and the Cilla Black of Sumatran Tigers. Plus, a sneak preview of this year's Genetics Society JBS Haldane lecture, and a gene of the month ...
10.13.2017 Evolution's luxury item You're a mammal. I'm a mammal. Your pet cat or dog is a mammal, as are whales, lemurs, pandas and polar bears. But what exactly is a mammal, and what can our genes tell us about our evolution? Plus, school ...
09.13.2017 Exposing the contents of your genes Would you ever consider donating your genome to research? We meet a man who has, and find out why. Plus, we get our hands dirty in the search for new antibiotics, take a look at the ethics of human gene ...
08.13.2017 Store, write, edit As scientists announce that they have used CRISPR technology to fix a faulty gene in a human embryo - not for the first time, but more accurately than ever before - we take a look at storing, writing and editing ...
07.13.2017 Genes and dementia This month we're taking a look at the role that genes play in dementia, and finding out how researchers are using this knowledge to develop urgently-needed treatments. Plus, a big release of big data from the UK Biobank, and our ...
06.13.2017 Bees, tress and 3-D genes This month we're literally getting inside our genes, as we explore chromosomes through a 3-dimensional virtual reality art, music and science project. Plus, researchers are turning to bees, trees and more in search of new genetic systems, and our gene ...
05.13.2017 Tackling tumours, curing cancer This month we're zooming in on cancer, finding out how researchers are tackling tumours in unprecedented detail. Plus, our gene of the month is the guardian of your genome, rather than the galaxy. Like this podcast? Please help us by ...
04.13.2017 Battle of the sexes We might joke about the battle of the sexes, but it turns out that this is actually true - at least for a hundred or so imprinted genes. Plus, what opossums can teach us about sex, reporting back from a ...
03.15.2017 Putting genomics to work The DNA sequencing revolution is providing ever more data about genomes from all kinds of species, from humans to bacteria. But how do we make sense of it all? Who gets their hands on it? And how do we use ...
02.14.2017 Science and the single cell Our bodies are made up of trillions of cells - but these aren't mere biological building blocks, as inert as bricks. They're constantly communicating and changing. So how do scientists measure this? Plus, you can now take part in an ...
01.14.2017 Genes, laws and Brexit We hear a lot about genetic modification and how it's being used to improve agriculture. But who decides whether modified crops can be grown? Do new gene editing techniques like CRISPR count as GM? And what happens to these regulations ...
12.14.2016 All human life is here The story of human evolution is long and complicated, but the simple truth is - you're only here because your ancestors got lucky. Plus, we wind the clock back to the very start of human life, and discover how new ...
11.14.2016 Searching for switches This month we're delving into the junk in the genome - or, to put it more correctly - our non-coding DNA. Less than 2 per cent of the human genome contains protein-coding genes, so what does all the rest do? ...
10.13.2016 Testing, testing We hear more than ever about the secrets hidden in our genes, from our risk of diseases to traits such as intelligence or even sporting ability. But can we really test for them? And just because we can, does that ...
09.13.2016 Hello Dolly This month we've got a special bonus-length podcast commemorating twenty years since the birth of Dolly the Sheep, the first mammal cloned from an adult cell. Her birth changed the scientific world, and led to the development of other transformative ...
08.13.2016 40 years of selfishness 40 years ago Richard Dawkins' The Selfish Gene hit the shelves. We look back on how it changed the way many people think about genetics. Plus, linking nurture to nature, and a gigantic gene of the month. Like this podcast? ...
07.13.2016 Signal to noise Building a baby is a complicated business, with millions of cells needing to work together. So how does it happen? Plus, how big data is making big strides in big genes, and our gene of the month is going round ...
06.13.2016 Genes for all Genes, genomes and genetic technology are playing increasingly important parts in our lives, industries, food and healthcare, and at a point in the not-too-distant future we're probably going to have to grapple with at least some of the contents of ...
05.13.2016 Check your compatibility You may not realise it, but your health, immune system and even love-life are governed by the particular set of so-called compatibility genes that you inherit. There are thousands of different variations in these genes, but why do we have ...
04.13.2016 What's in your genes? As the costs of DNA analysis come down, we've seen the rise of direct-to-consumer genetic testing, allowing anyone to spit in a tube, pop it in the post and get a personalised readout direct to their inbox. But what do ...
03.14.2016 Designer genes The recent invention of powerful precision tools for editing the human genome - known as CRISPR, has opened up new worlds of possibilities for researchers seeking to understand how our genes work - and also those who want to permanently ...
02.14.2016 Crazy for CRISPR It's the hottest new biotechnology technique to hit the headlines since well, since ever. CRISPR is a precision set of genome editing tools enabling scientists to cut and paste together DNA in any organism, exactly how they want - and ...
01.14.2016 Naked Genetics 47 This month we bring you a bumper edition, packed full of all our favourite bits from the past four years. Like this podcast? Please help us by supporting the Naked Scientists
12.14.2015 Naked Genetics 46 Synthetic biology - engineering life - is set to revolutionise the world, but how? We'll be hearing about some of the most exciting applications for synthetic biology, and how it's being commercialised. Plus, our gene of the month has got ...
11.14.2015 Why don't elephants get cancer? Animals like elephants and whales are made up of many more cells than a human, or a mouse, and they live far longer. Yet they hardly ever get cancer - and the big question is why? Plus, revolutions in genetics, ...
10.13.2015 Engineering life Imagine designing bacteria that can do whatever you want - from cleaning up oil spills to churning out the latest cancer treatments - ordering the biological parts online and building it in a couple of weeks. This is no longer ...
09.13.2015 Hundreds and Thousands When it comes to figuring out which genes and genetic variations are linked to particular traits and diseases, there's only one way to do it, and that's to go large, with cohort studies involving hundreds or even thousands of volunteers. ...
08.13.2015 Mysterious methylation There's more to life than the four letters of DNA, and our cells use a chemical tag known as DNA methylation to mark out certain parts of the genome, helping cells to remember what they're doing. And, as you might ...
07.13.2015 The wonderful world of epigenetics Genes are the instructions that tell our cells what to do, but how do different types of cells know which genes to switch on or off at the right time? The solution lies in epigenetics - the molecular bells and ...
06.13.2015 Breeding a better cow For centuries, breeders have been selecting plants and animals with desirable genetic traits. So how have some of these changes come about, and where will new genetic technologies take our food in the future? Like this podcast? Please help us ...
05.13.2015 The story of maize You may not realise it, but all the food you eat has been genetically altered over time by plant and animal breeders, capturing advantageous traits to grow more nutritious and easy-to-farm foods as efficiently and healthily as possible. Maize, or ...
04.13.2015 Patenting and preserving genes There are few things in life as important as the food we eat, but making sure that we guard the genes in our crops for the future is just as important. Plus, we take a look at some of the ...
03.14.2015 A hundred thousand genomes Over the past year the Government has unveiled an audacious programme under the banner of Genomics England, aiming to sequence the genomes of 100,000 people affected by cancer and rare genetic diseases. We take a look at some of the ...
02.14.2015 Genetically Modified plants Genetically modified, or GM, crops are a hot topic. Some people are deeply suspicious of the technology while others see it as an effective and efficient way of generating bountiful, healthier harvests. Plus, purple tomatoes, a giant of a gene ...
01.14.2015 Clever mice and drunken flies How do we learn complex tasks like playing the piano? Why can we remember things better after a good night's sleep? And why do people - and fruit flies - drink again after the hangover from hell? The answers are ...
12.14.2014 Searching for the engram For many years scientists have been searching for the mysterious engram - the place in the brain where memories are kept. And thanks to advances in genetics and neurobiology, it looks like they're now getting close to finding it. Plus, ...

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