Half a million genomes. That's how many the UK Biobank has, stored as blood samples in freezers up in Manchester. And in September 2019 they announced a project to sequence every single one of them. It's the obvious next step for the UK Biobank, the research study that began in 2006 and now consists of an enormous biological database: the personal and medical information of its 500,000 volunteers. That data is available to any researcher who applies to use it. But how is this, the biggest whole-genome sequencing project ever, going to work? Who's coughing up the hundreds of millions of pounds... Like this podcast? Please help us by supporting the Naked Scientists

It's a doggy dog world... in this episode we're talking pugs, bulldogs, and French bulldogs. They've all been bred for flat faces, but their airways haven't shrunk alongside their skulls - meaning that they often struggle to breathe. How has this happened? After evolving for millions of years, why are their airways literally too big to fit into their heads? Have they been betrayed by their own genes? Naked Genetics is on the case. Plus, the origin of puppy dog eyes, and we sequence the genome of Bruce the black lab puppy... Like this podcast? Please help us by supporting the Naked Scientists

Naked Genetics is back with new episodes every month! Today we're taking a step back. Where does genetics actually come from? How did we get to today's world of genome sequences and gene editing? It all started with a 19th-Century monk, working in his garden - but who was he really, and how did it take thirty years for him to be recognised? If you think you know this story, you might be surprised. Like this podcast? Please help us by supporting the Naked Scientists

Join Harvard DNA pioneer George Church and Chris Smith in conversation as they discuss gene cloning, DNA sequencing, decoding the mammoth genome, the risks posed by fossil viruses lurking in extinct genomes, the prospects of xenotransplantation and safety of gene therapy, and the risks of human CRISPR. The discussion was recorded on March 15th, live in front of a studio audience at the Hello Tomorrow Summit, in Paris, 2019... Like this podcast? Please help us by supporting the Naked Scientists

In November, He Jiankui claimed that two genetically engineered children have been born. Did he really do it? And if so, what are the ramifications for the babies and for the field? Georgia Mills explores the controversy in a special edition of Naked Genetics. Like this podcast? Please help us by supporting the Naked Scientists

We're returning to the scene of the crime with another look at the latest techniques in the world of forensic genetics - can we really predict physical features or even ethnicity from your DNA, and what does this mean for our criminal justice system? Plus, is the 'CSI effect' real? And our gene of the month would be more at home at a rave than a lab. Like this podcast? Please help us by supporting the Naked Scientists

We're off to a festival - but before you worry about where your tent and wellies are, it's the Festival of Genomics, held at a clean and dry conference centre in London rather than a muddy field full of rock bands and dodgy burgers. Plus, what does the public really think of genetic technology? And a fiery gene of the month. This is the Naked Genetics podcast for March 2018, brought to you in association with The Genetics Society. Like this podcast? Please help us by supporting the Naked Scientists

It's CSI Naked Genetics, as we find out how genetic technology is used to solve crimes. Like this podcast? Please help us by supporting the Naked Scientists

We take a trip back to the womb and before, to find out about early development. Plus, the importance of placentas, why the age of your womb rather than your eggs matters, and a video game-inspired gene of the month. Like this podcast? Please help us by supporting the Naked Scientists

This month we're finding out how genetic advances are shaping the future of healthcare at the Genetics Society autumn meeting. Plus, signposts for bees and an operatic gene of the month. Like this podcast? Please help us by supporting the Naked Scientists