How does the placebo effect work in the brain and body? The brain can jumpstart your immune system, and science is finally catching up.

In our second episode of Neural Compass, we explore one of the most mind-blowing frontiers in health: the connection between belief, biology, and the brain’s role in healing. Host Mark Jacobstein sits down with Dr. Asya Rolls — award-winning neuroscientist and professor of neuroimmunology — to discuss how the placebo effect isn’t just psychological… it’s physiological.

They cover:

- How the brain can activate the immune system

- The neuroscience behind placebo, hope, and healing

- Why the brain may be a key switch for turning on health

- What it means to measure — and harness — the will to get better

Learn more: jiminihealth.com

AI can detect your depression. And we have the data to prove it.

In our DEBUT episode of Neural Compass, we're kicking things off with a conversation that gets right to the heart of what this show is about — the intersection of AI, clinical care, and the future of mental and behavioral health. Host Mark Jacobstein sits down with Dr. Lyle Ungar — professor at UPenn and expert in machine learning, psychology, and language — to explore how AI is reshaping how we understand and care for the mind.

They cover:


- How language models are being used to pre-screen for depression


- The role of "synthetic friends" and when AI becomes too much of a crutch


- What it takes to move from mental illness to mental flourishing


- The future of AI-human collaboration in therapy

Learn more: jiminihealth.com

Welcome to Neural Compass, a new podcast from Jimini Health.

We’re charting the future of mental and behavioral health — at the intersection of AI, psychiatry, neuroscience, and real-world clinical care.

Hosted by Jimini’s own Mark Jacobstein, Neural Compass features honest, forward-thinking conversations with the leaders shaping what’s next — from healthcare executives to AI pioneers.

Whether you’re building in this space, investing in it, or navigating it as a decision-maker, this podcast is your guide to the breakthroughs, challenges, and ideas defining the next era of care.

Learn more: jiminihealth.com