The Autism Dad

Neuroinflammation and Autism: What Every Parent Needs to Know (Part 1) (S8E18)


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Could neuroinflammation be driving your child’s symptoms? This episode will change how you think about autism and health.

In this two-part series of The Autism Dad Podcast, I sit down with Dr. Theoharis Theoharides, one of the world’s leading experts in neuroimmune medicine and mast cell research. We dig deep into how inflammation in the brain—driven by overactive mast cells—can contribute to the struggles many autistic and neurodivergent kids face, including sensory issues, eczema, gut problems, chronic sinus issues, and even regression.


Dr. Theo doesn’t just talk theory—he shares actionable steps and science-backed insights that have the potential to improve quality of life for families like ours. I even share some personal stories about my sons, and how this research explains things we’ve experienced for years.

Whether your child is dealing with eczema, unexplained aggression, or GI issues, this episode may offer a new lens on what’s going on under the surface—and what you can do about it.

In this episode, we discuss:

  • What mast cells are and how they can impact the brain

  • How neuroinflammation may be linked to autism, ADHD, and chronic conditions

  • The surprising connection between eczema and autism

  • Why symptoms like gut issues and behavior changes are often misunderstood

  • The role of vitamin D, folinic acid, and glutathione in autism support

  • How stress can trigger mast cell activation and impact behavior

  • What testing and natural interventions parents can explore

  • How to think critically about supplements and avoid misleading claims

    This episode is sponsored by Safe Place Bedding

    Safe Place Bedding provides medically necessary, insurance-covered safety beds that help neurodivergent children sleep safely and securely—at home or while traveling. They’ve just launched the Safe Place 300, a permanent safety bed option with integrated monitoring. Visit https://safeplacebedding.com/theautismdad to learn more.


    If you found this episode helpful, please subscribe on Apple Podcasts, Spotify, or your favorite podcast app. You can also visit listen.theautismdad.com for more episodes, resources, and to leave feedback.

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