Central to modern biology and the study of life is the concept of the

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Our bodies and brains are radically transformable, mutable and plastic. From the neuroplasticity of the brain to the epigenetic malleability of our bodies and of all organic life, the work of the contemporary French philosopher Catherine Malabou invites us to consider our plasticity as both a creative resource and an ethical challenge.

Catherine Malabou and Contemporary French Literature and Film: Witnessing Plasticity (Edinburgh UP, 2026) brings Malabou's philosophy into dialogue with contemporary literature and film. It reads conceptions of plasticity and neuroplasticity in Malabou through the mutant bodies of Leos Carax's films; the shape-shifting bodies of Marie Darrieussecq's novels and theatre; the terrifying, traumatic metamorphoses depicted in the fiction of Marie NDiaye; and the anarchic sexualities and identities celebrated in the cinema and writing of Alain Guiraudie. It argues that, in different ways, Malabou's philosophy and literary and filmic texts develop modes of bearing witness to plasticity which can supplement, challenge and extend scientific understandings of biological plasticity, constituting ethical and creative sites of exploration.

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Professor Rina Bliss teaches in the sociology department at Rutgers University, and has written on the social significance of genetic studies on intelligence, race, and social factors.  

In What's Real About Race: Untangling Science, Genetics, and Society (W.W. Norton, 2025) Bliss explores the history of race as a genetic category, its haphazardness across research, medical, and social contexts, and its implications for knowledge production. In this work, Bliss sheds light on the real impacts of racism on bodies and lives, and on how these myths structure modern science and industries.

This interview is a conversation between Rina Bliss and a group of Princeton graduate students/visiting faculty involved in an interdisciplinary (IHUM) STS Reading group.

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MacArthur Fellow and National Humanities Medalist Rebecca Newberger Goldstein, author of Plato at the Googleplex and The Mind-Body Problem, returns with a revelatory book about the primal drive that in our species alone has been transformed into one of our most persistent and universal motivations: the longing to matter.

Drawing on biology, psychology, and philosophy, in The Mattering Instinct: How Our Deepest Longing Drives Us and Divides Us (Liveright Publishing, 2026) Goldstein argues that this need to matter―and the various “mattering projects” it inspires―is the source of our greatest progress and our deepest conflicts: the very crux of the human experience.
Goldstein brings this profound idea to life through unforgettable stories of famous and not-so-famous people pursuing their unique mattering projects: the ragtime genius Scott Joplin, whose dedication to his ignored masterpiece, Treemonisha, ended in tragedy; the pioneering psychologist William James, who rose above the depression of his young adulthood to become perhaps the first great theorist of mattering; an impoverished Chinese woman who rescued abandoned newborns from the trash; and a neo-Nazi skinhead who as a young man dealt racial violence to feel he mattered but ultimately renounced that hateful past after realizing that mattering isn’t a zero-sum game. These portraits illuminate how our instinct for significance shapes identity, relationships, culture, and conflict―and they point the way to a future where we all might see that there is, fundamentally, enough mattering to go around.
Deeply revealing and insightful, and decades in the making, The Mattering Instinct is a must read for those curious about why we seek to matter to ourselves and others―and how this insatiable longing that drives us apart may be the key to finally understanding each other.

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How living in space will affect future generations—and what the potential unintended consequences of space settlements are.
We are on the cusp of a golden age of space travel in which, for the first time, it will be possible for large numbers of people to venture into space. Some intend to stay. But what happens—and will happen—to us in the extreme conditions of space? What should space tourists expect to happen to them during a journey to an orbiting space station, the Moon, or Mars? What would happen to children born on another planet? Would they evolve into a new species? In Becoming Martian: How Living in Space Will Change Our Bodies and Minds (MIT Press, 2026) Scott Solomon explores the many ways in which humanity’s migration into space will change our bodies and our minds.
This book focuses on the latest science, taking readers to the front lines of research. We hear from astronauts, including Scott Kelly who writes the foreword, and we join a team of scientists guiding a rover across the surface of Mars. We visit a high-security lab where engineers are simulating space radiation to measure its effects on the body. We travel to isolated islands where field biologists are gleaning insights into evolutionary processes applicable to people isolated on faraway planets. We meet synthetic biologists developing gene-editing tools to equip future humans to thrive in alien environments. We watch a rocket designed to carry humanity to Mars make its first successful launch. And then we ask, knowing what we know: Should we go?

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Imagine a future where we grow houses rather than build them. Where smartphones are alive, clothing has opinions and all human knowledge fits into a speck of DNA. A world where disease is a thing of the past and the human lifespan is dramatically extended.
To achieve this, says Adrian Woolfson, founder of the genome writing company Genyro, we must transform biology into a predictive, programmable engineering material. That means decoding the generative grammar of DNA: the language of life itself. We will then be able to author genomes—and, if we choose, even rewrite our own.
In On the Future of Species: Authoring Life by Means of Artificial Biological Intelligence (MIT Press, 2026), Woolfson describes how we are at the cusp of a technological revolution, driven by the convergence of artificial intelligence and synthetic biology. Currently at the scribbling phase—writing the genomes of viruses, bacteria and yeast—we will eventually author the genomes of extinct and never-before-realized species. Life will become computable, detached from its past and no longer bound by Darwinian evolution.
While offering extraordinary opportunities, this power also carries great risk, and it is vital for everyone to understand what the future might hold. In this groundbreaking work, Woolfson provides a guide to this bold new world, offering a moral compass to help us do so safely, wisely and ethically.

Adrian Woolfson is the cofounder of Genyro, a California-based biotechnology company specializing in synthetic genome design and construction. He studied medicine at Balliol College, Oxford, and was formerly the Charles and Katherine Darwin Research Fellow at Darwin College, Cambridge, working at the MRC Laboratory of Molecular Biology.

Greg is the Executive Director and Founder of the World War II Discussion Forum (wwiidf.org). He also has a strong interest in literature, culture, religion, science and philosophy (translation: he's an eclectic reader who is constantly missing deadlines for book reviews).

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In Sex Isn’t Real: The Invention of an Incoherent Binary (Duke UP, 2026), Beans Velocci traces the history of current high stakes attempts to define sex and to create a world devoid of trans life. Drawing on lab notes, family genealogies, medical case studies, and more, Velocci follows scientists and clinicians from the mid-nineteenth through the mid-twentieth century and across five disciplines—zoology, eugenics, gynecology, statistical sexology, and transsexual medicine—as their ideas and practices created a definitional tangle. They demonstrate how the sorting of bodies into male and female persists not despite but because of sex’s incoherence: the defining features of these categories shift to contain various understandings of anatomy and physiology, theories of race, developments in research and medical methodologies, and bodies that cannot be accounted for in a binary framework. Exposing the endless work required to produce a world in which most people have a binary gender identity that neatly fits their binarily sexed body, Velocci demonstrates that it is not cis people who fit the categories; it’s the categories that flex to make them fit.

Beans Velocci is Assistant Professor of History and Sociology of Science and Gender, Sexuality, and Women’s Studies at the University of Pennsylvania.

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The cybernetic tradition in cognitive science analyzes the purposive behavior of many complex systems – from sensory-guided missiles to sensory-guided animals -- in terms of feedback control that maintains stability in the face of external perturbation. A more recent extension and elaboration of this framework brings in predictive processing and the minimization of free energy – essentially, minimizing getting inputs that conflict with what the system expects. In A Drive to Survive: the Free Energy Principle and the Meaning of Life (MIT Press, 2025), Kathryn Nave argues that this framework is inadequate for explaining living organisms, which are not merely complex but inherently unstable and continually producing themselves through metabolism. Nave, who is a Leverhulme Trust Early Career Research Fellow at the University of Edinburgh, defends a bioenactivist view of living organisms in which the chemical and energetic constraints involved in having a metabolism are essential for understanding their actions, in contrast to the “sensor-guided movementism” of the FEP framework.

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The Origins of the New (Princeton University Press, 2026) presents a revolutionary approach to evolutionary success in all realms of life. In this groundbreaking book, Douglas Erwin takes readers on a dazzling excursion across science and history to explore how evolution generates new and enduring features in biology, culture, and technology.
Erwin begins by tracing how thinkers from Darwin’s time to the present day have sought to discover the driving mechanisms of evolutionary novelty. He then lays out compelling empirical evidence for separating novelty from innovation, showing that novelty involves the emergence of unique characteristics, while innovation concerns the success of those characteristics over time. Erwin develops a unifying conceptual framework for these powerful dynamics, demonstrating how they have shaped everything from the evolution of avian feathers and flight to the creation of human language and the breathtaking advances in digital computing we’re witnessing today.
A landmark work that redefines our understanding of the changes happening all around us, The Origins of the New reveals how the forces of novelty and innovation are the same across nature and culture, continually producing new forms and refashioning the world as we know it.

Our guest is doctor Doug Erwin, who is an independent researcher at the Santa Fe Institute, after retiring as Senior Scientist and Curator of Paleobiology at the National Museum of Natural History of the Smithsonian Institution.

Our host is Eleonora Mattiacci, an Associate Professor of Political Science at Amherst College. She is the author of "Volatile States in International Politics" (Oxford University Press, 2023).

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The role of a resident vet in the remote islands of the Falklands, St. Helena, Ascension, and Tristan da Cunha encompasses many wonderful complexities: caring for the world’s oldest living land animal (a 200-year-old giant tortoise, denizen of the St. Helena governor’s lawn); pursuing mystery creatures and invasive microorganisms; relocating herds of reindeer; and rescuing animals in extraordinarily rugged landscapes, from subtropical cloud forests to volcanic cliff faces. Dr. Hollins’s tales of island vet life are not only full of ingenuity and astounding fauna—they are also steeped in the unique local cultures, history, and peoples of the islands, far from the hustle of continental life.

Our guest is: Dr. Jonathan Hollins, who graduated from Emmanuel College, Cambridge, and has been a working vet for four decades. Since the mid-2000s, he has spent long periods as a senior vet overseas in the South Atlantic. He has written for the British national press and presented documentary features for BBC Radio 3 and Radio 4. He lives on St. Helena.

Our host is: Dr. Christina Gessler, who is an academic writing coach and editor. She is the producer and show host of the Academic Life podcast.

Playlist for listeners:

Welcome to Academic Life, the podcast for your academic journey—and beyond! Please join us again to learn from more experts inside and outside the academy, and around the world. Missed any of the 300+ Academic Life episodes? Find them here. And thank you for listening!

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