N-Acetyl Cystine (NAC) has been long used as the antidose for acetaminophen poisonings - although with variable implementation. Join host, Geoff Wall, and guest, Kayla Myers, discuss a new consensus guideline for appropriate treatment of acetaminophen overdose.
 
The GameChanger
NAC should be used if any doubt of acetaminophen poisoning based on new consensus guidelines. NAC may be used continued beyond standard dosing for chronic or high amounts of acetaminophen.
 
Host
Geoff Wall, PharmD, BCPS, FCCP, BCGP
Professor of Pharmacy Practice, Drake University
Internal Medicine/Critical Care, UnityPoint Health

Guest
Kayla Myers, PharmD
Clinical Pharmacist
Unity Point

Reference
Dart RC, Mullins ME, Matoushek T, et al. Management of Acetaminophen Poisoning in the US and Canada: A Consensus Statement. JAMA Netw Open. 2023;6(8):e2327739. doi:10.1001/jamanetworkopen.2023.27739

https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2808062

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CPE Information
 
Learning Objectives
Upon successful completion of this knowledge-based activity, participants should be able to:
1. Apply the new modified Rumack-Matthew nomogram to a potential acetaminophen poisoning
2. Discuss the use of fomepizole in the use of acetaminophen overdose

0.05 CEU/0.5 Hr
UAN: 0107-0000-23-300-H01-P
Initial release date: 9/11/2023
Expiration date: 9/11/2024
Additional CPE details can be found here.

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