Hello my fellow Hemp nuts! Are you ready for the cannabis bonanza?!
Welcome to the New Hemp Times show recorded at Gotham Studio, the sweetest smelling podcast studio in the world. Today’s episode is partially powered by McSorley’s Chilli Dogs, McSorley Ale house, the oldest ale house in the United States. Also, powered by Five and Dimes Old Fashioned, hand crafted by Erin.
We have a fun show for you today!
Segments:
Our word of the day is tinctures.
Research: Lancet article on Psychosis and cannabis.
We will test your knowledge of recent cannabis news and science.
And time permitting we will provide a Q&A about PTSD and cannabis and other issues in the hemp and cannabis space.
We are joined by Jan Roberts, our resident clinician and LCSW, CEO of the IRCCMH.
Also participating today is the Unapologetic Farmer, Randy Cameroon, Jr. CEO of Brooklyn Sprouts Social Enterprises, engaging in one of the most radical things you can do, grow your own food and medicine in an urban environment. Working with Interfaith medical center
And from HBO’s crashing, performing every week in Manhattan, living the dream, Greer Barnes!
And, of course Dr. J (aka Jahan Marcu,Ph.D)
Word of the day: Tincture - Notes below:
What is a tincture you may ask? Tinctures are liquid extracts made from herbs that you take orally (by mouth). They are usually extracted in alcohol (known here on our website as "regular"), but they can also be extracted in vegetable glycerine or apple cider vinegar (non-alcohol). Tinctures are easy and convenient to use. Tinctures are also easier to give to children as they have to take only small amounts (see Children's Dosage Guide for suggestions). Because they are taken directly under the tongue, they enter the bloodstream much more quickly and directly than by any other means. This means that the action in the body is usually quicker. Although some herbs will have an immediate effect, such as those used to help one relax, others that are more nutritive and building in nature may take several weeks of continual use before best results are seen (much like a multi-vitamin).
In the 19th century, the Irish surgeon O’Shaughnessy reintroduced the use of cannabis from India into Western medicine. Cannabis sativa L. (Cannabaceae)—largely in the form of ethanolic tinctures—was then part of main Western pharmacopoeias until the 1930s, when it was removed gradually with increasing recreational use and its legal prosecution
In the second half of the 19th century, over 100 scientific articles were published in Europe and the United States about the therapeutic value of cannabis.13 The climax of the medical use of cannabis by Western medicine occurred in the late 19th and early 20th century. Various laboratories marketed cannabis extracts or tinctures, such as Merck (Germany), Burroughs-Wellcome (England), Bristol-Meyers Squibb (United States), Parke-Davis (United States), and Eli Lilly (United States).
As non-alcohol tinctures have no alcohol content to them to act as a preservative, they can easily become contaminated and are at risk for growing mold.
Alcohol, pregnancy and drug interactions: One dose of an alcohol-based tincture has approximately the same alcohol content as eating a very ripe banana
Sativex is licensed in about 30 countries, an insane about of gold standard clinical research is published about this product, which is essentially a tincture with a spray nozzle.
LANCET ARTICLE, additional articles:
https://www.thelancet.com/action/showPdf?pii=S2215-0366%2819%2930048-3
https://nypost.com/2019/03/20/daily-marijuana-use-linked-with-higher-risk-of-psychosis-study/
https://www.npr.org/sections/health-shots/2019/03/19/704948217/daily-marijuana-use-and-highly-potent-weed-linked-to-psychosis
https://www.rollingstone.com/culture/culture-news/marijuana-psychosis-lancet-study-810568/
https://thehill.com/opinion/healthcare/435448-will-smoking-cannabis-make-you-psychotic-not-likely
Tools for Understanding Lancet data:
Odds ratio
OR=1 Exposure does not affect odds of outcome
OR>1 Exposure associated with higher odds of outcome
OR<1 Exposure associated with lower odds of outcome
The 95% confidence interval (CI) is used to estimate the precision of the OR. A large CI indicates a low level of precision of the OR, whereas a small CI indicates a higher precision of the OR. It is important to note however, that unlike the p value, the 95% CI does not report a measure’s statistical significance. In practice, the 95% CI is often used as a proxy for the presence of statistical significance if it does not overlap the null value (e.g. OR=1). Nevertheless, it would be inappropriate to interpret an OR with 95% CI that spans the null value as indicating evidence for lack of association between the exposure and outcome.
Cannabis News- Finding or Fiction
CBD Concentration, Supply Chains Will Be Questioned by FDA During April Public Comments
https://www.law.com/corpcounsel/2019/03/22/attorneys-cbd-concentration-supply-chains-will-be-questioned-by-fda-during-april-public-comments/?kw&slreturn=20190226205817
Blue Moon's creator launched a cannabis beer that sold out in 4 hours | Yahoo Finance
https://sports.yahoo.com/blue-moons-creator-launched-a-cannabis-beer-that-sold-out-in-4-hours-140044104.html
Seth Rogen teams up with Canopy Growth to launch cannabis brand Houseplant | Financial Post
https://business.financialpost.com/pmn/commodities-business-pmn/agriculture-commodities-business-pmn/seth-rogen-teams-up-with-canopy-growth-to-launch-cannabis-brand-houseplant-2
People are lining up to grow marijuana for research. Trump's Justice Department won't let them. | Vox
https://www.vox.com/policy-and-politics/2019/3/26/18277629/marijuana-legalization-research-trump-dea-justice-department
NBC’s Tom Brokaw Reveals He Takes Medical Marijuana to Relieve Pain From Cancer | Daily Beast
(TX) Texas Lawmakers Approve Marijuana Decriminalization In Committee Vote | Marijuana Moment
https://www.marijuanamoment.net/texas-lawmakers-approve-marijuana-decriminalization-in-committee-vote/
(INT) Could a Giant Wooden Bong Revive the Town of Woodenbong, Australia?
https://merryjane.com/news/could-a-giant-wooden-bong-revive-the-town-of-woodenbong-australia
Woodcarver Paul Pearson wants Woodenbong, New South Wales to commission a massive wooden bong to draw business to his small, economically struggling hometown.
“Tourists would travel from all over the world just to experience our tremendous and fully functional working wooden Godzilla bong, the same way they do to climb the Story Bridge,” wrote John Birmingham.
The CBD gold rush has begun
Suddenly, CBD is everywhere. https://www.cnn.com/2019/03/26/success/cbd-entrepreneurs/index.html
Cannabis Science: Findings or Fiction
Smoking tobacco along with marijuana increases symptoms of cannabis dependence
(“The average smoker in non-poverty areas of Manhattan and the East Village/Lower East Side used joints/pipes – and used them while alone – more often than blunts. The average smoker in Harlem/South Bronx used blunts – and used them while alone – more often than joints.) Researchers concluded part of the study by stating “This finding suggests that rather than smoking joints while alone and blunts in groups, the average Harlem/South Bronx smoker simply prefers blunts for all occasions.”
Ream, G. L., Benoit, E., Johnson, B. D., & Dunlap, E. (2008). Smoking tobacco along with marijuana increases symptoms of cannabis dependence. Drug and Alcohol Dependence, 95(3), 199–208. http://doi.org/10.1016/j.drugalcdep.2008.01.011
Blunts versus joints: Cannabis use characteristics and consequences among treatment-seeking adults.
Consistent with existing literature (Schauer et al., 2017), African Americans were more likely than other racial/ethnic groups to report smoking blunts in the past month, respectively. The elevated rates of blunt use are at least partially due to the aggressive marketing and price promotion of LCC products, especially flavored LCCs that are commonly used to make blunts (Delnevo et al., 2015; Ribisl et al., 2017; Sterling et al., 2016), in communities with high proportions of young adult and African American residents.
ttps://www.ncbi.nlm.nih.gov/pubmed/30901744
(NAT) States With More Immigrants Are More Likely To Legalize Marijuana, Study Finds | Marijuana Moment
https://www.marijuanamoment.net/states-with-more-immigrants-are-more-likely-to-legalize-marijuana-study-finds/
A study recently published in the journal Contemporary Drug Problems offers some answers. Researchers looked at each state’s marijuana laws and analyzed their political, demographic, economic and social characteristics to identify various trends.
History of Lifetime Cannabis Use Is Associated with Better Cognition and Worse Real-World Functioning in Schizophrenia Spectrum Disorders.
https://www.ncbi.nlm.nih.gov/pubmed/30897572
In conclusion, our data show that lifetime cannabis use, but not in the last year, is associated with better working memory and processing speed and worse real-world functioning in the area of socially useful activities in patients with schizophrenia-related disorders. While this may be surprising, we think that in fact it could represent some clinical differences between cannabis-induced psychosis and psychosis per se.
Does cannabis improve cognitive function but make it harder to work, study? Is this research contrived or just controversial?
In this study, they demonstrated that cannabis use throughout life is not related to the functioning of patients, neither in the area of personal and social relationships nor in the area of personal care; it was also not related to disturbing and aggressive behaviour. But socially useful activities such work and study appears to be negatively affected.
Exploring perceptions among people who drive after cannabis use: Collision risk, comparative optimism and normative influence.
https://www.ncbi.nlm.nih.gov/pubmed/30896069
Among the participants in the remedial driving program, researchers, based on sruvey data, found that friends of participants were generally seen as more accepting of DUIC than family, and responses from participants, that data indicated there were indications that the opinions of others who use cannabis were regarded as more credible than the opinions of those who do not use the drug.
Do cannabis users only believe other cannabis users when it comes to driving safety?
Are we on the road to enlightenment or am I driving on the wrong side of the street?
CBD has been shown to Protect the Heart from Damage due to the Chemotherapeutic agent, Doxorubicin
Science/Animal: Activation of the CB2 receptor may prevent from damage to the heart by doxorubicin
In a study with rats administration of beta-caryophyllene, which activates the CB2 receptor protected from the heart damaging effects of doxorubicin, a chemotherapeutic agent used for the treatment of cancer.
College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, United Arab Emirates.
Meeran MFN, et al. Chem Biol Interact. 2019 Mar 2. [in press]
In the UK ,Reclassifying cannabis based drugs has not made accessing them easier, MPs hear.
https://www.ncbi.nlm.nih.gov/pubmed/30894360
Other Stuff
Minority Cannabis Business Association Model Municipal Social Equity Ordinance March 6, 2019
https://minoritycannabis.org/wp-content/uploads/2019/03/Final-Draft-of-MCBA-Model-Municipal-Social-Equity-Ordinance-v.1.pdf
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