Alex Harris, Head of Global Policy at the Wellcome Trust and the BBC's Fergus Walsh tell us about promising progress on a coronavirus vaccine. Video-sharing app TikTok has denied that it is controlled by the Chinese government; Emily Taylor, associate fellow with the International Security Programme at Chatham House, tells us why countries like India and the US are not reassured by TikTok's guarantees about the safety of users' data. Office workers are still in many cases, working from home and there is a growing realisation that this is having a huge knock on effect on small retailers who rely on that footfall. The BBC's Dougal Shaw meets one retailer in London, whose family-run chain of small shops sells gift cards, wrote to the BBC explaining his plight. Civil rights leader and congressman, John Lewis, died last week; we hear about his life from Erika Alexander, co-founder of Color Farm Media and producer of the film John Lewis: Good Trouble. And our regular workplace commentator, Pilita Clarke, considers whether coronavirus marks the end of the era of hot-desking in the modern office. Plus, we're joined throughout the programme by Christine Spadafor, a management consultant and lawyer - she's in Maine on the east coast of the US and in Delhi, India we're joined by Madhavan Narayanan, a freelance writer and former senior editor at Hindustan Times. (Picture of a vaccine via Getty Images.)