This podcast continues the conversation with Consuelo Wilkins, MD, MSCI, on how to improve inclusion, diversity, and equity in pragmatic clinical trials. Susan L. Mitchell, MD, MPH, moderated the discussion as they answer questions from Dr. Wilkins’ Grand Rounds and expand on these very important ideas shared during the talk.

IMPACT members Brent P. Forester, MD, MSc and Ula Hwang, MD, MPH continue the conversation from their March 18 Grand Rounds webinar presentation on giving updates on two IMPACT funded pilot studies. The IMPACT Collaboratory funds several one-year pilot studies annually; these are meant to generate the preliminary data necessary to design and conduct a future full-scale Stage IV effectiveness ePCT (based on the NIH Stage Model) funded through other grant mechanisms (National Institutes of Health or other sources).

Stuart Nicholls, PhD, from the Clinical Epidemiology Program at the Ottawa Hospital Research Institute ,continues the discussion from his February 18 Grand Rounds presentation. This discussion with IMPACT Principal Investigator Susan Mitchell, MD, MPH answers questions from Dr. Nicholls's presentation on giving an overview of ethical issues raised by pragmatic randomized controlled trials (RCTs) and which derive from ongoing work to develop guidance for those designing and conducting pragmatic RCTs.

Ab Brody, PhD, RN, FAAN, Ellen McCreedy, PhD, MPH and Jessica Colburn, MD continue their conversation from their January 13 Grand Rounds webinar presentation. This discussion with IMPACT Principal Investigator Susan Mitchell, MD, MPH answers questions from their presentation on providing real world examples of implementation in ongoing AD/ADRD ePCTs in different health care settings.

Scott D. Halpern, MD, PhD, John M. Eisenberg Professor of Medicine, Epidemiology and Medical Ethics & Health Policy at the University of Pennsylvania Perelman School of Medicine continues the conversation from his December 17 Grand Rounds webinar presentation. This discussion with IMPACT Principal Investigator Vince Mor, PhD, covers questions from Dr. Halpern's presentation on improving serious illness care through large pragmatic trials.

Enola K. Proctor, PhD, Shanti K. Khinduka Distinguished Professor at Washington University's Brown School of Social work continues the topics discussed during her Grand Rounds presentation on implementation outcomes and their role in treatment success with IMPACT Executive Director Ellen McCarthy, PhD.

Eric B. Larson, MD, MPH and Joseph E. Gaugler, PhD continue the topics discussed during their Grand Rounds on the AHRQ and Lancet Reports on dementia interventions, interpretation and implications for embedded pragmatic trials with IMPACT Executive Director Jill Harrison, PhD.

IMPACT Collaboratory Podcast 9: Data-related Challenges for Pragmatic Trials Involving PLWD by NIA IMPACT Collaboratory

Eric Larson, Leah Hanson, David Reuben, and Jeff Williamson of the IMPACT Health Care Systems Core dive deeper into their discussion on how embedded pragmatic trials can benefit both health care systems and the research community. IMPACT PI Vince Mor moderates.

Executive Director for the IMPACT Collaboratory Jill Harrison speaks with Laura C. Hanson, MD, MPH and Sheryl Zimmerman, PhD about their recent IMPACT Collaboratory Grand Rounds. The Grand Rounds focused on finding pragmatic and relevant outcomes for AD/ADRD ePCTs.