What makes a blockbuster, or a box office bomb? The truth is, as famed screenwriter William Goldman put it, “Nobody knows anything.” Join us each week as we put your favorite actors, directors, and writers through the wringer (aka through a series of games) to see if they’ve got what it takes to make it in this wild town.

This episode is all about coming-of-age stories — movies and TV shows about first loves, schoolyard scrapes, and the realization that the world is far bigger than the block you live on.

Guests: Actor, writer and director Natasha Lyonne (“Poker Face,” “Russian Doll”); actor and comedian Sherry Cola (“Joy Ride,” “Nobody Wants This”); director and Oscar-winning screenwriter Cord Jefferson (“American Fiction”).

NOBODY KNOWS ANYTHING s hosted by Franklin Leonard, founder and CEO of The Black List, a platform that helps Hollywood discover great scripts. The show is a production of The Black List and LAist Studios, in partnership with The Ankler.

Support for this podcast is also brought to you by Gordon and Dona Crawford, who believe that quality journalism makes L.A. a better place to live.

MORE ON LAIST: "'Nobody Knows Anything' is here to make you (and me) smile more"

New episodes premiere Tuesdays and you can listen to the show on the radio at LAist 89.3 on weekends. The premiere episode is supported by presenting sponsor FX.