This episode of the Physics World Weekly podcast features an interview with Panicos Kyriacou, who is chief scientist at the UK-based start-up Crainio. The company has developed a non-invasive way of using light to measure the pressure inside the skull. Knowing this intracranial pressure is crucial when diagnosing traumatic brain injury, which a leading cause of death and disability. Today, the only way to assess intracranial pressure is to insert a sensor into the patient’s brain, so Crainio’s non-invasive technique could revolutionize how brain injuries are diagnosed and treated.

Kyriacou tells Physics World’s Tami Freeman why it is important to assess a patient’s intracranial pressure as soon as possible after a head injury. He explains how Crainio’s optical sensor measures blood flow in the brain and then uses machine learning to deduce the intracranial pressure.

Kyriacou is also professor of engineering at City St George’s University of London, where the initial research for the sensor was done. He recalls how Crainio was spun out of the university and how it is currently in a second round of clinical trials.

As well as being non-invasive, Crainio’s technology could reduce the cost of determining intracranial pressure and make it possible to make measurements in the field, shortly after injuries occur.