In this episode of The Augmented Life, Michael Tiffany sits down with Adam Greenfeld, Co-Founder at Thesis Nootropics.

They unpack the science and strategy behind brain enhancement, from the early Reddit-fueled experiments that shaped Thesis, to the surprising audiences using nootropics today.

Adam opens up about dopamine burnout, self-experimentation, how he evaluates if a stack is working, and why optimizing for "life experience" now beats waiting for a big exit.

Whether you're deep into biohacking or just curious how to improve task switching and mental clarity, this conversation blends rigorous science, personal reflection, and practical strategies you can use today.

—

⏱️ Timestamps

00:00 – Welcome to The Augmented Life

01:09 – How do you pronounce "nootropics"?

02:57 – Science vs. woo: intuition as real data

04:38 – Adam’s seasonal approach to objectivity vs. energy

05:45 – Stress, inflammation, and felt results

08:05 – The limits of pharmaceutical science vs. biohacking

10:02 – The original Thesis testing protocol: 2,500 participants

13:26 – 130+ ingredients tested, 85% match accuracy

16:26 – Why being non-precious with formulations worked

18:23 – Innovation vs validation in supplement design

19:39 – From biohackers to SoulCycle execs: Who uses Thesis

22:48 – The “busy mother” demographic and shifting audiences

24:11 – Adam’s nuanced POV on Adderall over prescription

26:36 – Why Stasis is for people staying on Adderall

27:50 – The dopamine receptor burnout theory

29:05 – The real addiction: stress and complexity

31:17 – Daily stack: creatine, clomiphene, magnesium, clean eating

36:34 – Hydrogen tablets, walking, ocean therapy, and woo

38:40 – Still taking Thesis: 7 years, 5 days a week

40:10 – Optimize for life experience, not just exit strategy

43:28 – How to measure if nootropics work

45:51 – Sub-perceptual vs. felt effects: a product design insight

47:27 – Task switching speed: a killer metric for high performers

48:22 – Where to find Adam + links to Thesis & Stasis

🎧 Subscribe for more conversations like these

#nootropics #biohacking #dopamine #thesisnootropics #selfoptimization #adderralsupport #augmentedlife #brainhealth #creatine #taskswitching #founderstory #mentalperformance #takethesis #takestasis #adamgreenfeld