The brain is a daunting therapeutic challenge. This year's edition of Neuropsychopharmacology Reviews provides an update on treatments for brain disorders ranging from schizophrenia to neurodegeneration. Join Kerri Smith as she talks to Gwenn Smith, editor of this year's volume, about current therapies such as drugs, electrical stimulation and cognitive therapies, and the future of neurotherapeutics in an era of uncertain funding.

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Cognition is perhaps the ultimate brain function - encompassing complex abilities like learning, memory and language. Join Kerri Smith as she talks to Trevor W. Robbins, volume editor of this year's Neuropsychopharmacology Reviews on cognition, about how the brain mediates our sense of time, the roles of neurochemicals like dopamine and glutamate in brain function and behavior, and how to translate basic findings into therapies for disorders like depression, schizophrenia and ADHD.