omega tau - English only

omega tau - English only

By Markus Voelter, Nora LudewigScienceNatural Sciences
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omega tau - English only episodes

  • 366 - The Viper Gliding Club

    Guest: Jens Trabolt Host: Markus Voelter Shownoter: Tim Jurik

    Image Credit for the Air-to-Air Foto: @JacekSiminski and @DawidKamizela, DefensePhoto.com

    My guest Jens and I have two things in common: we both fly gliders, and we both got to fly in an F-16. Which is why we form the Viper Gliding Club :-) Jens is a Danish journalist and got to fly with the Danish Air Force in one of their F-16Bs. In this episode we compare notes on our experiences, appreciate the commonalities and discuss the differences.

    Note: In the intro I say that Jens flew with the Dutch Air Force. That is of course wrong, he flew with the Danish Air Force. I knew that, obviously, but the words are so similar that I messed them up.

    Introduction - Jens Trabolt 00:01:47

    Nordic Gliding | Jens' Flight at Nordic Gliding

    Background of flight opportunity 00:07:31

    Pre-flight Training and Preparation 00:12:57

    ACES II seat | Fouga CM.170 Magister

    Aircraft and Flight Discussion 00:38:27

    General Dynamics F-16 | North American X-15 | Valsalva maneuver

    Dreams to Reality - Taking the controls 01:05:07

    What's next after going supersonic? 01:18:07

    1 hr 37 min
  • 364 - Physics beyond the Standard Model

    Guest: Valerie Domcke Host: Markus Voelter Shownoter: Andy Joiner

    A while ago we had a whole series about LHC, ATLAS and particle physics in general. Despite all we know about what our world is made of and the explanatory power of the standard model, there is also a variety of open questions and currently unexplained phenomena. These include dark matter, dark energy, the neutrino mass, the CP violation, the hierarchy problem, and of course the unification of the standard model with gravitation. In this episode, CERN’s Valerie Domcke explains what it’s all about.

    Introduction 00:03:11

    Physics Beyond the Standard Model | Valerie Domcke | CERN | Particle Physics | Cosmology | Standard Model

    Dark Matter 00:05:31

    Dark Matter | Matter | Gravity | Radiate | Black Hole | Bend Light | Interaction | Neutrino Detector | Weak Interaction | Parameter Space | Free Parameter | Mass/Charge/Spin | Xenon | WIMP | Axions | Strong CP Problem | QCD | Primordial Black Hole | Supersymmetric WIMP | General Relatively | Bullet Cluster

    Dark Energy 00:22:20

    Dark Energy | Accelerated Expansion of the Universe | Red Shift | Cosmological Constant | Einstein's Biggest Blunder | Vacuum Energy | Cosmic Microwave Background (CMB) | Opaque Universe | Quintessence | Multiverse | String Theory

    Neutrino Mass 00:39:45

    Neutrino Mass | Left Handed/Right Handed Particles | Quantum Charge | Generation | KATRIN Experiment

    CP Violation 00:47:47

    CP Violation | Antimatter | Hydrodynamics Equations | Annihilate | Electrogenesis | Antiparticle | Yukawa Coupling | Baryon number | Leptogenesis | Baryogenesis | Higgs Field | C-Symmetry | Parity | Quantum Field Theory | Grand Unified Theory

    Hierarchy Problem 01:08:45
    Hierarchy Problem | Fermion | Gauge Boson | Loop Corrections | Planck Scale | Supersymmetry | Slepton | LEP Experiment | WIMP Miracle

    Unification with Gravitation 01:24:16

    Graviton | Classical Theory | Discretized | String Theory | Local Minimum

    Close 01:30:59

    Mathematica | Analytical Analysis | Differential Equations | Simulation

    1 hr 43 min
  • 359 - Modern Fission Reactors

    Guest: Jacopo Buongiorno Host: Markus Voelter Shownoter: Andy Joiner

    In this episode we take a look at newer generations of fission reactors, those that are currently being developed or researched. Our guest is Jacopo Buongiorno of MIT. We discuss some of the high-level goals of these new reactors, such as increased safety and efficiency, and then look at a few of the interesting new designs and how they realize these goals. We also briefly cover some of the policy arguments around keeping fission in the mix for combatting climate change.

    Introduction 00:08:18

    Jacopo Buongiorno | Nuclear Science and Engineering | MIT | Advanced Nuclear Technology | Reliability | Decarbonization | Fission | Fusion | Nuclear Power Plant | Primary Energy Source | Turbine | Electric Generator | Grid | Condenser | Reactor Core | Uranium | Nuclear Binding Energy | Chernobyl | Meltdown | Cooling | Intrinsically Unstable | Radioactivity | Decay Heat | Redundancy | Passive Safety | Control Rods | Irradiated | 3-Mile Island | 3-Mile Island | Retrofitted

    Existing Reactors 00:20:28

    Light-Water Reactor | Pressurized Water Reactor | Boiling Water Reactor | Radioactive Waste | Decommissioning | Lifecycle Cost | Final Repository | Dry Casks | Energy Mix | Renewables | CO2 Emissions

    Small Modular Reactors 00:37:39

    Small Modular Reactors | Mass Production | Neutron Spectrum | Thermal Neutrons | Moderator | Uranium Dioxide Pellets in Rods | AP1000 | Common Cause Failure | Previous German Episode on Nuclear Power Plants

    High Temperature Reactors 00:49:41
    TRISO | Pebble Bed | Molten Salt Reactor | Fast Reactor

    Micro Reactors 01:07:24

    Micro Reactor | 40ft Container | Heat pipe | Desalination | Breeder | Burner | Plutonium | Reprocessing

    Safety 01:23:46

    Negative Void Reactivity Coefficient | Criticality | Critical Mass

    Listener Questions 01:33:44

    Instrumentation | Modeling | Indirect Measurement

    Big picture 01:39:14

    NuScale Power | Thermal-Hydraulics | Two-Phase Flow

    1 hr 55 min
  • 355 - Supercomputing for COVID-19

    Guests: Andrew Emerson, Daniel Jacobson
    Host: Markus Voelter Shownoter: Andy Joiner

    In this episode we look at how supercomputers are used to help with managing the pandemic. It’s a double-header with two guests. We start with Cineca‘s Andrew Emerson. As part of the EXSCALATE 4 COV EU-funded research project, he works of virtual screening of existing drugs regarding their potential efficacy against SARS-CoV-2. In part two we talk with Dan Jacobson of the Oak Ridge National Laboratory. He and his team used a big data analysis to understand how the virus “works”, and they figured out very interesting mechanisms and pathways.

    Introduction 00:03:14

    Andrew Emerson | Cineca Supercomputer Center | Exscalate4Cov Project | Computer Aided Drug Design | Simulation | Modelling | Synthesize | Side Effects | Active Ingredient | COVID-19 | SARS-CoV-2 | Virus | Drug Repurposing/Drug Repositioning | Toxicology | Virtual Screening | Protein | Enzyme | Cell | Replication | Inhibit | DNA | Cell Membranes | Amino Acid | RNA | Gene | Gene Expression | Genome | Lock and Key Model | Screening | Virtual Screening | Dompé | Parallel Process | Abstraction (PDB - Protein Data Bank)  | Bonding | Experimental data (Proteins - accurate 3d data | Drug molecules - basic data)  | X-Ray Diffraction | NMR | Cryogenic Electron Microscopy | Electromagnetic Force | Van der Waals Force | Electrostatic Interaction | LiGen | Molecular Docking | Toxicology | Few seconds per molecule for virtual screening

    Molecular Dynamics Simulation 00:31:06

    Molecular Dynamics Simulation | Thermal effects | Stable State | Statistical techniques | Numerical Simulation | Newton's Laws of Motion | Bond vibration | Coulomb's law | Multi-Body Problem | Unfold | Molecular dynamics simulation can take about a week | Clustering | Degrees of Freedom | Energy Surface | Boltzmann Distribution | Virtual screening filtered ~400,000 possible drugs to ~7000 to go to the laboratory | Vaccine | Immune Response | ~100 of ~7000 screened molecules were interesting | In Vitro Tests | 40 effective molecules limited virus replication | Antiviral | Cortisone

    Computer Software and Hardware 01:09:44

    GROMACS | Open Source | GPU | Homology Model | C++ | CUDA | Marconi 100 | Galileo Linux Cluster | Eni | HPC5 | Nvidia V100 | Scheduling

    Results 01:20:24

    Raloxifene | Clinical Trials | Dimer | Protease | Physical Chemistry | Computational Chemistry | Vector (Biology) | Vector (Mathematics)

    Bradykinin Storm Analysis 01:30:59

    Dan Jacobson | Computational Systems Biologist | Oak Ridge National Laboratory (OLCF - Oak Ridge Leadership Computing Facility)  | Evolution | Pathogenicity | 3D Structure | Human pathogenesis | Demographic factors | Bradykinin Storm Paper | 17000 samples across 57 different tissues | Regulatory circuits | Bronchoalveolar Lavage fluid | Bronchoscope | Terminal Bronchioles | Luminal surface | Gas Exchange | Pathways (RAS - Renin-Angiotensin System)  | Blood Pressure | Inflaitory RResponses | ACE2 | Cell Entry | ACE | Proteolytic Enzyme | Proteolytic cleavage | Peptide | Hypertensive | Upregulated (Ang-(1-9) - Angiotensin (1-9))  | AGTR2 receptor | Receptor | Bind | Kallikrein Kinin Pathway | C1-Inhibitor Protein | Biosynthesis | Vasodilation | Hyperpermeability | Plasma | Capillaries | Immune Cells | Transcription | Hyaluronic Acid | Hydrogel | Tropism | Renin | Vitamin D | Catabolise | Metabolite | Expression | Calcifediol | Icatibant | Dexamethasone | Phospholipase A2 | Arachidonic Acid | Cascade | Chemotaxis | Combinatorial Therapies

    Computational Tools 01:56:58

    Machine Learning | Functional Inference | Explainable AI | Data Analytics | ChIPseek | Transcription Factors | Traits | Phenotypes | Combinatorial Space | P-Values | Permutation Tests | Neural Network | Black Box | Classification Problem (IRF - Iterative Random Forests)  | Decision Tree | Iterative Approach | Summit Supercomputer | Flash Memory | Gordon Bell Prize 2018 | Tensor Cores | Matrix Multiplication | Exascale Barrier | Hyperparameter Sweeps | Monte Carlo Simulation | R | Python | Parsers

    2 hr 29 min
  • 350 - Existential Risk

    Guests: Toby Ord Host: Markus Voelter Shownoter: Jochen Spalding

    Humanity has always been exposed to potentially catastrophic risks that might endanger the continued existence of humanity. Asteroid impacts or supervolcano eruptions come to mind. But since about the invention of the atomic bomb, humanity has been able to wipe itself out, adding self-made existential risks to the natural ones. Oxford philosopher Toby Ord argues in his book The Precipice that those risks are much more likely than the natural ones. In this episode we explore this idea with him, and also discuss what we should do about this realization.

    Introduction 00:02:22

    Toby Ord | Toby Ord | Nick Bostrom (OT 275 - Technikfolgenabschätzung)  | Anthropogenic hazard (Toby Ord - The Precipice: Existential Risk and the Future of Humanity | John Leslie - The End of the World: The Science and Ethics of Human Extinction Hardcover | George Orwell - 1984)  | Extinction event (OT 184 – Societal Complexity and Collapse)  | Joseph Tainter | Derek Parfit (Derek Parfit - Reasons and Persons)  | Game theory | Chicxulub impactor | Global catastrophic risk | Gamma-ray burst | Likelihood-ratio test | List of nuclear close calls | Nuclear winter

    Concrete Risks 00:47:20

    Dissolution of the Soviet Union  | Strategic Arms Reduction Treaty | Free-rider problem | Positive feedback loop | Methane Feedbacks to the Global Climate System in a Warmer World | Runaway greenhouse effect | The moist greenhouse limit | Increased insolation threshold for runaway greenhouse processes on Earth-like planets | Biotechnology | Pandemic | Killer rabbit virus on the loose | 1978 smallpox outbreak in the United Kingdom | Biosafety level | Faulty pipe blamed for UK foot and mouth outbreak | Tokyo subway sarin attack | Bioterrorism | Synthetic genomics | CRISPR | Gene drive | Artificial intelligence

    Why do we care? 01:21:48

    Utilitarianism | Special relativity | Nihilism | International organizations | The Chronicles of Narnia (C. S. Lewis - The Chronicles of Narnia)

    Epilog mit Markus und Nora 02:02:18

    2 hr 41 min
  • 348 - ATLAS Computing

    Guests: Frank Berghaus Host: Markus Voelter Shownoter: Bastian Hundt

    To conclude our detailed look at the ATLAS experiment, this episode looks at the computing infrastructure. We start out with the trigger systems that decide, very quickly, whether the data from a particular collision is worth keeping. We then discuss the reconstruction of the event, the simulation needed to understand the background as well as the LHC Grid used distribute data and computation over the whole planet. Our guest is CERN’n Frank Berghaus.

    Introduction of Frank Berghaus 00:03:45

    Frank Berghaus | omega tau about the History of ATLAS | omega tau about Science at ATLAS | CERN | The Atlas Experiment | LHC

    Basic Structure of LHC/Atlas and the Computing Infrastructure 00:05:25

    Particle Physics | Particle Accelerator | Particle Detector | Beamline | Magnetig Field | Calorimeter | Atlas Calorimeter | Energy | Muon | Analog to Digital Converter | Particle Collision | Atlas-Trigger | In-Memory-Cache | Resistive Plate Chambers | Photomultiplier Tube

    Terminology 00:17:05

    Reconstruction / Reduction | Data Processing | Online vs. Offline | Cern Datacenter | Bias

    After Event-Trigger Data Processing 00:23:10

    Electron Shower | Network Switch | Cryostat | Round-Robin Schedueling | Distributed Storage | Event Horizon Telescope

    Data Processing after Storage of Events 00:42:45

    Particle Jets | Momentum | Abstraction

    Jet Reconstruction 00:51:25

    Topological Clustering | Cone Algorithm

    Processing and Reprocessing / CERN Computing Infrastructure 01:03:55

    Luminosity | High Luminosity LHC | Vertex Detector

    LHC Computing Grid 01:12:40

    Worldwide LHC Computing Grid

    Analysis of Events and Computing Infrastructure 01:24:05

    Simulation | Field Theory | Differential Equations | Photon | ROOT Particle Physics Software | Machine Learning | GPU | Multithreading | Supercomputer

    Data Organization and End 02:00:25

    Relational Database | Namespace | Tape Storage | Cloud Computing | Distributed Computing | Standard Model

    CERN File System 02:18:45

    CVMFS | Docker

    2 hr 47 min
  • 345 - ATLAS Science

    Guests: Philipp Windischhofer Host: Markus Voelter Shownoter: Andy Joiner

    After understanding the history and development of ATLAS (and covering the LHC and particle physics in general) in previous episodes, we are now at the point where we can try to understand how a scientist uses the data produced by one of these large detectors and make sense of it. This is what we’ll do in this episode with physicist (and listener) Philipp Windischhofer. If you want to learn even more, you can check out these links provided by Philipp or read the last chapter of the book :-)

    Some additional material supplied by Philipp:

    • All ATLAS physics papers
    • The Higgs analysis paper we spoke about in the episode
    • The press release that goes with it
    • Public lecture by my favourite physicist on “why the Higgs has to exist”
    • On the hierarchy problem
    • ROOT data analysis framework
    • Introduction 00:03:23

      Philipp Windischhofer | Particle Physics | University of Oxford | Atlas Collaboration | Atlas Detector (Episode 030 – The Large Hadron Collider)  | Large Hadron Collider (LHC) | CERN | Higgs Boson (Episode 093 - Standard Model)  | Other episodes on particle physics

      Particle Physics 00:05:03

      Special relativity | Quantum Mechanics | Mass | Charge | Spin | Symmetry | Angular Momentum | Quantized | Graviton | Gravitational Waves | Quark | Color Charge | Strong Interaction | Weak Charge | Weak Interaction | Four Point Interaction | Wave-Particle Duality | Virtual Particles | Quantum Field Theory | Matter Particles | Force-Carrier Particles | Boson | Fermion | UA1 Experiment | UA2 Experiment | Cross Section | Mexican Hat Potential | Spontaneous Symmetry Breaking | Sigmas | FCC | GeV | Hierarchy Problem

      Atlas Experiments 00:59:13

      Collision | Momenta | Proton | Sub-detectors | Interaction-point | Pixel Detector | Magnetic Field | Gas Based Tracking Detector | Transition Radiation Tracker (TRT) | Calorimeter | Electromagnetic Calorimeter | Hadronic Calorimeter | Muon System (Gas Detectors) | Right-hand Rule | ~2MB data per event | Bunch | Visualizations | Event Reconstruction | Energy Deposits | Extrapolate | Noise | Combinatorics | Tracking | Tracklet | Kalman Filter | Data Fusion | Showers | Jet | Jet Clustering Algorithm | Pileup | Calibration | Model | Integration | Simulation | CAD Model | Bootstrapping | Monte Carlo Methods | Numerical Methods

      Physics in ATLAS 01:55:28

      Decay | Decay Rate | Boosted | Associated Production | Candidates | ROOT file | Degrees of Freedom | Plot/Histogram | Distribution | Maximum Likelihood Fit | Discretize | Artificial Neural Networks | Boosted Decision Tree | Discriminant | Distance Metric | Blinded | Athena | C++ | Python | Effective Theory

      3 hr 3 min
    • 344 - History and Development of ATLAS

      Guests: Peter Jenni Host: Markus Voelter Shownoter: Alexander Grote

      ATLAS is one of the two general-purpose experiments at the LHC. It has been conceived, designed, and built over decades by hundreds of scientists and engineers from dozens of countries and hundreds of organizations. My guest, Peter Jenni, has been the head of the ATLAS collaboration for most of this time. In this episode we talk about science and engineering, but mostly about organizational aspects and the “community management” necessary to get such a magnificent machine off the ground.

      Introduction Peter Jenni 00:02:55

      Peter Jenni | LHC | CERN | Atlas | University of Bern | ETH Zürich | SLAC | Fabiola Gianotti | LEP | Intensity | electrons | positrons | protons

      The Atlas Experiment Overview 00:18:40

      solenoid magnet | magnetic field | right hand rule | electromagnetic calorimeter | the Atlas liquid Argon Calorimeter | Hadrons (Mesons and Baryons) | TileCal | Muons | CMS | Particle Collider | ALICE | LHCb | Bottom Quark | Standard Model | Weak interaction / intermediate vector bosons | UA1 | UA2 | SPS | Super Proton–Antiproton Synchrotron | Simon van der Meer | Carlo Rubbia | Dipole Magnet | SSC | Higgs Boson | Luminosity | Higgs Mechanism | Supersymmetry | WIMPs | Supersymmetric Dark Matter

      Design Decisions in Atlas 01:39:39

      Tracking Detector | Atlas Tracker | Decay | Decay length (Lecture Particle Decay Slide 9) | Superconductivity | Atlas Technical Design Report

      Outlook 02:08:15

      LS2 | HL-LHC | LHC Quench | European Strategy for Particle Physics | ILC

      2 hr 40 min
    • 343 - Flying and Testing the F-35

      Guests: Tucker Hamilton Host: Markus Voelter Shownoter: Thomas Machowinski

      The Lockheed F-35 Lightning II is going to be more or less what the F-16 and F-18 are today: the backbone of the US and NATO land and sea-based air forces. It is a multi-role fighter, and one of its versions has the capability to take off with a very short roll and land vertically. Tucker “Cinco” Hamilton is a test pilot who has flown all three versions of the jet. In this episode we talk about flying this fifth-gen fighter and about some aspects of the testing program. For more F-35 and Cinco check out episode 78 of the Fighter Pilot Podcast.

      • Cinco on Instagram
      • Cinco on TikTok
      • Introduction with Tucker Hamilton 00:01:56

        Lockheed Martin F-35 | F-35A -> Conventional CTOL | F-35B -> Short takeoff and vertical landing | F-35C -> Carrier-based

        Flying the F35 00:11:23

        Fully Fly-by-wire | HOTAS "hands on throttle-and-stick" | F-35 Cockpit from simulator | Distributed Aperture System (DAS) | ILS Instrument Landign System | Radius fight

        Testing the F-35 00:36:53

        Testing at Wikipedia | Edwards Air Force Base | CAS Calibrated Airspeed | Probe-and-drouge Air Refueling

        Noble Eagle Mission 01:03:57

        Operation Noble Eagle | Temporary Flight Restriction | Cessna 172 | Tail Number

        1 hr 15 min
      • 341 - Emergency and Intensive Care, Ventilation

        Guests: Kimon L. H. Ioannides, Junad Chowdhury Host: Markus Voelter, Nora Ludewig
        Shownoter: Jochen Spalding

        In light of the current situation, we have decided to record a couple of episodes that cover some of the relevant background in terms of biology, medicine and healthcare. In this first episode we discuss emergency care and intensive care with a special focus on ventilation. We discuss these topics in general, and also specifically to COVID-19. Our guest, Kimon and Junad, are both practicing doctors and have practical experience with these topics.

        Introduction of the Guests 00:03:28

        Dr. Kimon L.H. Ioannides | Dr. Kimon L.H. Ioannides (Twitter) | Junad Chowdhury

        Basics of Emergency and Intensive Care 00:04:24

        Airway-Breathing-Circulation (ABC) | Cardiopulmonary resuscitation (CPR) | Monitoring | CT scan | Shock (circulatory) | Psychological trauma | Distributive shock | Sepsis | Anaphylaxis | Hypovolemic shock | Cardiogenic shock | Obstructive shock | Covid-19 | Personal protective equipment (PPE) | Ebola virus disease | Hypoglycemia

        Ventilation 00:39:56

        Sympathetic nervous system | Post-intensive care syndrome | Nasal cannula | Non-invasive ventilation | Negative pressure ventilator | Oxygen toxicity | Pneumonia | Pulmonary function testing | Extracorporeal membrane oxygenation (ECMO) | Continuous mandatory ventilation | Patient-ventilator asynchrony | Pulmonary alveolus | Adrenaline | Central venous catheter (Central line) | Acute respiratory distress syndrome | Tracheotomy | Ventilator-associated pneumonia | Parenteral nutrition

        1 hr 48 min

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