• Trade – Zofran
• Class – Antiemetic 
• MOA – Binds and blocks a receptor for the brain chemical serotonin 
• Indication – Prevention and treatment of nausea and vomiting
• Contraindication – Use caution in hypokalemia, hypomagnesemia, cardiac arrhythmias 
• Side Effects – headache, fatigue, diarrhea, dizziness, hypotension/HTN, Prolonged PR and QT intervals, Widened QRS, Bradycardia, tachycardia, syncope. 
• Dosage

Adult: 4– 8mg IV, IO, PO

Pedi: (2-16 years) 0.15 mg/kg IV,IO ( max dose 16mg)