The David Nurse Show

Optimizing Salt, Hydration, & Cardiovascular Health | James DiNicolantonio


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On today’s episode of The David Nurse Show, cardiovascular researcher and pharmacist, Dr. James DiNicolantonio, sets the record straight on one of the most misunderstood nutrients—salt. Far from being the enemy, sodium is essential for performance, focus, energy, and cardiovascular health. During his conversation with David, James explains why most people are chronically under-consuming salt and how this impacts everything from fatigue to hormonal health.


Together David and James explore how low salt levels can increase insulin resistance, stress hormones, and even cravings, creating a dangerous cycle that sabotages physical and mental performance. James also breaks down how proper sodium intake improves endurance, sleep, and stress resilience—and gives specific guidance on how to tailor salt intake based on your activity level and lifestyle. This episode is a must-listen for athletes, entrepreneurs, and anyone wanting to perform at their highest level.


CHAPTERS:

00:00 Introduction to Dr. James DiNicolantonio

01:32 Why Salt Is Not the Enemy

03:45 The Real Science Behind Sodium and Blood Pressure

06:10 Hydration Myths That Hurt Performance

08:05 Signs of Salt Deficiency in High Performers

10:22 How Low Salt Increases Insulin and Stress Hormones

13:01 Optimizing Sodium for Energy and Focus

15:17 Best Forms of Salt and Electrolyte Supplements

18:00 How to Personalize Your Salt Intake

20:04 Final Takeaways on Salt, Health & Longevity

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The David Nurse ShowBy David Nurse

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