While paediatric onset multiple sclerosis is relatively rare, it presents unique challenges. Extensive research efforts are taking place around the world to better understand the disease mechanism of paediatric MS and the similarities and differences that exist with adult onset MS to help determine the best treatment options for children and adolescents. In this episode, host Brett Drummond of MSTranslate explores the topic with Dr. Yael Hacohen of Great Ormond Street Hospital for Children and UCL Institute of Neurology in the UK and Dr. Thaís Armangué of SJD Barcelona Children's Hospital in Spain.